Epidemic complications in the territory of Gorno-Altai high-mountain natural plague focus, associated with increase in numbers of carriers and vectors of the dangerous diseases, entailed strengthening of preventive element in the system of epidemiological surveillance. Objective of the study was to assess the efficiency of disinsection and deratization during anti-epidemic campaign. Materials and methods. Investigations were performed in 2014-2017 in the territory of Kosh-Agach district of the Republic of Altai, based on the archival and operational records from Altai Plague Control Station, Rospotrebnadzor Administration in the Republic of Altai, and our own data. “Interactive Map on Management of Health Promotion Measures in Gorno-Altai high-mountain natural plague focus” was used as an assessment tool. Results and conclusions. The most hard-hitting sections of preventive complex as regards plague are still disinsection and deratization. Application of advanced methods and means of control over numbers of carriers and vectors of the infection testify to their high anti-epidemic effectiveness. Insecticide and rodenticide treatments of encampments situated in epizootic areas, disinsection and deratization in major population centers in the territory of the focus allowed for the reduction in risk of population infection. Technical efficiency of the field disinsection amounted to 96.7 %, community deratization and disinsection varied from 91.6 to 100 %. Emergency insecticide and rodent treatments in epizootic areas alongside other measures provided for epidemiological welfare on plague.

Objective of the study is to sum-up the results of prophylactic (anti-epidemic) measures associated with elimination of epidemic focus in Kosh-Agach Region of the Republic of Altai in 2016. Materials and methods. Utilized were the data of reporting and source documentation from Altai Plague Control Station, Rospotrebnadzor Administration in the Republic of Altai, RusRAPI “Microbe”, and Irkutsk RAPI. Results and conclusions. It is pointed out that carried out in 2016 complex of organizational, anti-epidemic, and sanitary-prophylactic activities against plague is the importnant stage of rehabilitation of Gorno-Altai high-mountain natural plague focus, the final goal of which is maximally possible decrement of risks of primary human infection with plague, and in case of occurrence of such – performing of prompt response measures on localization and elimination of epidemic focus. It has been substantiated that for epidemic risk minimization in 2017 it is necessary to continue prophylactic vaccination, desinsection and deratization in the areas of predictive epizootic situation aggravation, which is contained in “Complex Action Plan of the Rospotrebnadzor Institutions for Sanitation and Rehabilitation of Gorno-Altai high-mountain natural plague focus in Kosh-Agach Region of the Altai Republic in 2017”. It is also necessary to provide for implementation of the Program on lowering risks of importation from cross-border Sailyugemsky natural focus and spread of plague in the territory of the Russian Federation, within the frames of RF Government Order No 1864-p, dated 05.09.2016.

Results of the analysis of the increase in the incidence of epidemic of the West Mle fever and climate conditions in the Volgograd region were presented. certain seasonal periods and threshold values of temperature and humidity statistically associated with the epidemic rise were identified. The discussion of the probable mechanisms of indirect effects of atmospheric heat on the elements of the epidemic process was carried out.