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1Особенности Геморрагической Лихорадки С Почечным Синдромом, Вызываемой Генетическими Подтипами Вируса Добрава/Белград В России

Е. А. Ткаченко,Dzagurová Tk,В. Г. Морозов,Ю. В. Юничева, Г. П. Слюсарева,Н. С. Седова, А,Н. А. Коротина,Boris Klempa, Д. Крюгер

2008Pacific Medical Journal

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2[Discovery, Clinical and Etiological Characteristic of Hemorrhagic Fever with Renal Syndrome in the Subtropical Zone of Krasnodar Region].

T K Dzagurova,E A Tkachenko,Iu V Iunicheva,V G Morozov,A F Briukhanov,V N Bashkirtsev,N S Sedova,B Klempa,D Kruger

Twenty-six patients with hemorrhagic fever with renal syndrome (HFRS) were revealed as a result of serological examination of 582 patients with fever living around Sochi town. Etiologic role of Dobrava virus subtype as the cause of HFRS was assessed by immunofluorescent and ELISA assays, and neutralization test. The principal host of this virus and source of infection for humans is Caucasian forest mouse Apodemus ponticus. HFRS morbidity was sporadic and not dependent from patients' occupation and season. Comparative analysis of clinical and laboratory data from HFRS cases caused by DOB/Sochi and DOB/Lipetsk subspecies, as well as Puumala virus showed higher proportion of severe forms of disease in patients with HFRS from Sochi.

2008Zhurnal mikrobiologii epidemiologii i immunobiologii（2008）引用：27

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3Сравнительная Характеристика Геморрагической Лихорадки С Почечным Синдромом, Вызываемой Хантавирусами Пуу Мула И Добрава

В. Г. Морозов,Ю. В. Юничева,А. Ф. Брюханов, Г. П. Слюсарёва, И В Сикора,Dzagurová Tk,В Н Башкирцев,Н. С. Седова, В. И. Рощупкин, Е. А. Ткаченко

2007Medical news of the North Caucasus（2007）

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4[Epizootology of Hemorrhagic Fever with Renal Syndrome in the Central Chernozem Region].

A E Balakirev,V N Bashkirtsev,N S Sedova,N M Okulova,D V Trankvilevskiĭ, I V Sikora, S M Frolova, E N Luz'ianov, N, A F Sapel'nikov,E A Tkachenko

A total of 5149 small mammals belonging to 16 species were collected from the Lipetsk, Voronezh, and Belgorod regions (40 administrative districts) in 2003-2004 and examined by ELISA and IFA to detect hantavirus antigen and antibodies in the lung tissues. Hantavirus circulation was revealed in 13 species, the highest hantavirus activity being detected in field (Apodemus agrarius) and small wood (A. (S) uralensis) mice (Dobrava-Belgrad virus), bank (Clethrionomis glareolus) (Puumala virus) and common (Microtus arvalis) (Tula virus) voles. These species were frequently found to have their untypical hantaviruses, which was most commonly observed in small wood mice. It is suggested that the small wood mouse is likely to take a certain part in maintaining the circulation of Dobrava-Belgrad virus.

2006Voprosy virusologii（2006）引用：25

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5[The Epizootological and Virological Characteristics of a Natural Hantavirus Infection Focus in the Subtropic Zone of the Krasnodarsk Territory].

E A Tkachenko,N M Okulova,Iu V Iunicheva,S P Morzunov, S F Khaĭbulina,T E Riabova,L E Vasilenko,V N Bashkirtsev,T K Dzagurova,E A Gorbachkova,N S Sedova,A E Balakirev,

A natural focus of hantavirus infection was detected and examined during the studies conducted in 2000-2002 around the Sochi (the western spurs of the Great Caucasus Ridge, which descended to the Black Sea (the Krasnodar Territory of Russia). At least 4 rodent species, such as Microtus majori, A. (S.) ponticus, A. agrarius, A. (S.) ciscaucasicus, were shown to participate in the circulation of hantaviruses. A comparative analysis of the nucleotide sequences of genomic S- and M-segments of hantaviruses has provided evidence that 13 viral RNA isolates from the A. (S.) ciscaucasicus belong to the Dobrava/Belgrade virus clade; however the RNA isolate from the Microtus majori belong to the Tula virus clade.

2005Voprosy virusologii（2005）引用：32

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