BACKGROUND: The number of people with intestinal stomas in Russia reaches 140 thousand people according to the registry of stoma patients. For any outcomes stoma on the anterior abdominal wall has an extremely negative effect on the body image and quality of life of this patient.AIM: Validation and cultural adaptation of the CIS questionnaire in the Russian Federation.MATERIALS AND METHODS: The official translation of the CIS questionnaire was performed according to current WHO and EORTC guidelines. The study involved 209 patients from 9 centers (3 national and 6 regional) from different districts of Russia.RESULTS: The stoma impact on quality-of-life questionnaire showed an inverse negative relationship with the EORTC QLQ-C30 global quality of life scale, physical, role, emotional and social functioning (all p<0,05).CONCLUSION: The CIS Questionnaire reliably identifies a group of patients with a significant impairment in the quality of life and can be used in Russia.