The clinical observation presents a rare case of a patient with arterial tortuosity syndrome, with a 9-year follow-up of the clinical picture dynamics.

A case of ICA aneurysm is presented, all possible pathogenesis mechanisms that led to the formation of an aneurysm are analyzed. In the analysis of the clinical case, mathematical modeling confirmed the assumption of the relationship between biomechanical conditions in the aneurysm area, regardless of etiology.

The article presents a rather rare clinical observation and literature review of surgical interference for mycotic (infectious) aneurysm of the suprarenal aorta with damage to paired and unpaired branches (celiac trunk, superior mesenteric and renal arteries). The authors note the features of the clinical course of aortic lesions (chronic ischemia of the digestive system, cardiorenal hypertension), the mechanisms of the disease development, and indicate the need for open repair of the thoracoabdominal aorta.

The review covers the first studies of the vessels of the brain. The history of the emergence and development of the doctrine of protecting the brain during operations on the carotid arteries is given. Experience has been accumulated in the development of the doctrine of surgical protection of the brain during primary operations on the carotid arteries and compression of the carotid arteries. The analysis of existing and existing methods was carried out. Based on the above analysis, ways of further development of methods of protecting the brain during operations on the carotid arteries are shown.

Background. COVID-19 is represented by a large number of different phenotypes, ranging from asymptomatic progress to the development of severe multiple organ dysfunction syndrome. The mechanisms of development of multiple organ dysfunction syndrome are multifactorial, including hypercoagulation with the formation of blood clots. They are often diagnosed as thrombotic complications with detection of blood clots not only in the veins and pulmonary arteries, but also in the heart and main arteries. An observational study shows that the incidence of venous and arterial thrombosis is as high as 31% in patients with COVID-19 pneumonia. However, large studies have not yet been conducted.Aim. To generalize and analyze our own observations of the clinical course of patients with thrombosis and COVID-19.Methods. The study included 5 male patients who had arterial and venous thrombosis and COVID-19 positive test. Results The experience of treatment of 5 patients with COVID-19 with arterial and venous thrombosis was analyzed. All patients showed characteristic changes in the coagulogram. The patient who, upon admission, had a negative test for COVID-19, and characteristic changes in the coagulogram appeared on the day of recurrent thrombosis, was of greatest interest. All patients received standard treatment and were discharged with improvement after testing negative for COVID-19.Conclusion. Generalization of the clinical course of patients with COVID-19 and thrombosis of various vascular regions allowed us to develop treatment tactics for these groups of patients.

Introduction . Pulmonary embolism (PE) is potentially life-threatening complication that could develop in hormonal contraceptive users. Therapeutic thrombolysis is safe, relatively modern and effective method of treatment. Aim of the study — to summarize our own experience of thrombolytic therapy of PE in women OC users. We presented three cases of PE developed in association with oral contraceptive use. Tree female patients aged 20 years, 34 years, 47 years at admittance to hospital were diagnosed PE. Result . All patients got thrombolytic therapy with alteplase 100 mg iv (10 mg bolus iv, then 90 mg continuous iv injection by infusomat). Good clinical outcomes were reached in all cases. Conclusion. Our experience shows that alteplase is highly effective agent in PE treatment in women with TE after hormonal contraception. Keywords: hormonal contraception; venous thrombosis; pulmonary embolism; thrombolysis.

This article describes the experience of the high-frequency ultrasound system using in the assessment of the microcirculation after surgery hemorroidektomy. The three levels of microcirculation disorders were identified, correspondingto the results of treatment. The advantage of ultrasonic scalpel was proved.

Presence of concomitant anal canal pathology (anal fissure, rectum intrashincteral fistula) is contraindication for miniinvasive treatment. Thereby new methods development of miniinvasive treatment is carrying out.