Система пуриновых нуклеотидов 1: мембранные механизмы физиологических эффектов производных аденина / К. Я. Буланова [и др.] // Военная медицина. - 2012. - №4.-С.102-108.

In this study, we have engineered Escherichia coli strains overproducing recombinant enzymes undine phosphorylase, thymidine phosphorylase, purine nucleoside phosphorylase, adenosine deaminase, lysyl-tRNA synthetase and nucleoside phosphotransferase The whole cells or isolated enzymes were applied as biocatalysts for the synthesis of compounds of pharmaceutical interest, particularly arabinosides of adenine and guanine, ribosides of thymine, 6-furfurylaminopurine (kinetin) and 6-benzylaminopurine, 5-bromovinyl-2'-deoxyuridine, 2',3'-dideoxy-adenosine and - guanosine, arabinofuranosyladenine-5'-monophosphate, diadenosine-5',5'''-P-1,P-4-tetraphosphate (Ap(4)A) etc Under optimal conditions the indicated compounds were formed in the reaction mixtures in 55-96% yields after 1 5-7 h