The economic crisis, that occurred nearly two year ago, has affected on campaigning all sectors to cut back their spendings and buying local made products in order to reduce national currency reserve. Drugs or pharma ceutical products are considered as manufactured goods that are relied on imported raw materials that represented 35-50%of the local manufactured pharmaceutical product cost. For import finished products, it represents 80-100% of the cost. With this import dependency, there is no doubt that the impact of economic crisis on pharmaceutical business would be unavoidable. This study was aimed at describing and analyzing the situation and problems of drug management system and utilization in the Ministry of Public Health hospitals, recommending measures for drug management reform.