This article contains brief overviews, mechanisms and practical details for organic synthesis named reactions and processes beginning with the letter ‘I’. Reactions included in this section are: IRELAND Allyl Ester Rearrangement; IVANOV Carboxy-Grignard Reagent

This article contains brief overviews, mechanisms and practical details for organic synthesis named reactions and processes beginning with the letter ‘Y’. Reactions included in this section are: YAMADA Peptide Coupling; YAMAGUCHI Lactonization Reagent; YAMAMOTO Homoallylamine Synthesis; YAMAMOTO Chiral Allylic Displacement; YAMAMOTO Supersilyl Sequential Aldol; YAMA Z AKI Cyanoaniline Synthesis; YAMA Z AKI Guanine Synthesis; YONEMITSU 3-Component Condensation

This article contains brief overviews, mechanisms and practical details for organic synthesis named reactions and processes beginning with the letter ‘K’. Reactions included in this section are: KABACHNIK–FIELD Aminophosphonate Synthesis; KABE Chromanone Synthesis; KAGAN–HORNER–KNOWLES Asymmetric Hydrogenation; KAGAN–MODENA Asymmetric S Oxidation; KAGAN – MOLANDER Samarium Reagent; KAHNE Sulfoxide Glycosidation; KAISER–JOHNSON–MIDDLETON Dinitrile Cyclization; KAKIS Oxidative Aryl Rearrangement; KALUZA Isothiocyanate Synthesis; KAMETANI Amine to Nitroalkane Oxidation; KATRITZKY Amine Displacement; KATRITZKY–Li Stereoselective Ester Olefination; KAUFFMANN Arene Dimerisation; KAWASE N -Acyl Rearrangement; KECK Radical Allylation; KEINAN Iodosilane Reagent; KENNEDY Oxidative Cyclization; KHARASCH–SOSNOVSKY Allylic Oxidation; KHUN–WINTERSTEIN Olefin from Diol Synthesis; KILIANI–FISCHER Sugar Homologation; KINUGASA β-Lactam Synthesis; KIRMSE–DOYLE Sulfonim Ylide Rearrangement; KNOCHEL Cu Zn C C Coupling; KNOEVENAGEL Cinnamic Acid Synthesis; KNORR Quinoline Synthesis; KNUNYANTS Fluoroalkylation; KOCH–HAAF Carboxylation; KOCHI Cross Coupling; KOCHI Chlorodecarboxylation; KOCIENSKI–FUJISAWA Selectively Subsituted Alkene Synthesis; KOENIGS–KNORR Glycosidation; KOHLER Isoxazole- N -oxide Synthesis; KOLBE Carboxylic Acid Electrolysis; KOLBE–SCHMIDT Salicylic Acid Synthesis; KONAKA Nickel Oxidizing Agent; KOENIG Benzoxazine Synthesis; KORNBLUM Aldehyde Synthesis; KOSER Tosylation; KOTHA–SCHOLLKOPF Glycine Equivalent; KOWALSKI Ester Homologation; KRAPCHO De-alkoxycarbonylation; KRESZE Amination Agent; KRISCHE Asymmetric Reductive C C Coupling; KROHNKE – ORTOLEVA Keto Pyridinium Salts; KUCHEROV–DENIGES Mercuric Catalyzed Hydration; KUIVILA–BECKWITH Radical Dehalogenation; KULINKOVICH Hydroxycyclopropanation; KUMADA C C Coupling; KURSANOV–PARNES Ionic Hydrogenation

This article contains brief overviews, mechanisms and practical details for organic synthesis named reactions and processes beginning with the letter ‘D’. Reactions included in this section are: DAKIN Phenol Oxidation; DAKIN–WEST Ketone Synthesis; DANHEISER Silylallene Annulation; DANISHEFSKY Dienes; DARAPSKI Amino Acid Synthesis; DARZENS Epoxide Synthesis; DARZENS–NENITZESCU C C Acylation; DAVIDSON Oxazole Synthesis; DAVID–THIEFFRY Monophenylation of Diols; DAVIES Fe Chiral Auxiliary; DAVIS–ELLMAN Chiral Sulfinimines; DAVIS Oxaziridine Oxidizing Reagent; DE KIMPE Aziridine, Amidine Synthesis; DE MAYO C C Photocycloaddition; DELEPINE Aldehyde Oxidation; DELEPINE Amine Synthesis; DEMJANOV Diazonium Rearrangement; DESS–MARTIN Alcohol Oxidizing Reagent; DIECKMANN Diester Cyclization; DIELS–ALDER Cyclohexene Synthesis; DIELS–ALDER ASYMMETRIC Reaction; DIMROTH R-N Rearrangement; DIMROTH Triazole Synthesis; DJERASSI–RYLANDER RuO 4 Oxidating Agent; DOEBNER–MILLER Quinoline Synthesis; DOERING Alcohol Oxidation; DOERING–La FLAMME Allene Synthesis; DONDONI C O Homologation; DOTZ Hydroquinone Synthesis; DOWD Cyclic Ketone Ring Expansion; DUFF Aromatic Aldehyde Synthesis; DUTHALER–HAFNER Enantioselective Allylation; DUTT–WORMALL Azide Synthesis

This article contains brief overviews, mechanisms and practical details for organic synthesis named reactions and processes beginning with the letter ‘M’. Reactions included in this section are: MACDONALD Porphyrin Synthesis; MADELUNG Indole Synthesis; MAKOSZA Vicarious Nucleophilic Substitution; MAMEDOV Heterocycle Rearrangement; MANDER Methoxycarbonylation Reagent; MANN Ether Dealkylation; MANNICH Aminomethylation; MARKOVNIKOV Regioselectivity; MARSCHALCK Aromatic Alkylation; MARTIN Dehydrating Reagent; MASCARELLI Fluorene Synthesis; MATTESON Asymmetric Boronic Esters; MATTOX–KENDALL Dehydrohalogenation; Mc MURRY Carbonyl Coupling; McCORMACK–KUCHTIN–RAMIREZ Phosphole Synthesis; McFADYEN–STEVENS Ester Reduction; MEERWEIN Alkylating Reagent; MEERWEIN–PONNDORF–VERLEY Reduction; MEINWALD Epoxide Rearrangement; MEISENHEIMER–JANOVSKY Aromatic Complex; MEISENHEIMER N-Oxide Rearrangement; MELDRUM’S Acid; MENCKE–LASZLO Nitration of Phenols; MERRIFIELD Polymers and Peptide Synthesis; MEYER–SCHUSTER Propargyl Rearrangement; MEYERS Chiral Oxazoline; MICHAEL Conjugate Addition; MICHAELIS–NYLEN Phosphonylation; MIDLAND Asymmetric C O Reduction; MIESCHER Acid Chain Degradation; MIGITA–SANO Quinodimethane Synthesis; MILAS Olefin Hydroxylation; MILLER–SNYDER Aryl Cyanide Synthesis; MILSTEIN Alcohol Amidation; MINAMI Thiourea Dioxide Reducing Agent; MINISCI Free Radical Substitution; MISLOW–BRAVERMAN–EVANS Sulfoxide Rearrangement; MITSUNOBU Nucleophilic Displacement; MOORE Cyclobutenone Rearrangement; MORIN Penicillin Rearrangement; MORITA–BAYLIS–HILLMAN C O C C Coupling; MOSHER’S ACID for Chirality Determination; MOUSSERON–FRAISSE–McCOY Cyclopropanation; MUKAIYAMA Aldolization; MUKAIYAMA Lactonization Reagent; MUKAIYAMA–UENO Selective Diol Oxidation; MUNDY N -Acyllactam Rearrangement; MURAHASHI Allylic Alkylation; MYERS–SAITO Cycloaromatization

This article contains brief overviews, mechanisms and practical details for organic synthesis named reactions and processes beginning with the letter ‘Z’. Reactions included in this section are: ZARD Radical Aminomethylation via Xanthates; ZAV‘YALOV Pyrrole Synthesis; ZEISEL–PREY Ether Cleavage; ZEISS Ketone Transfer; ZIMMER Lactone (Lactam) Rearrangement; ZIMMERMAN (Oxa) Di-π-Methane Rearrangement; ZINCKE – SUHL Cyclohexadienone Synthesis; ZININ Benzidine (Semidine) Rearrangement; ZINKE – ZIEGLER Calixarene Synthesis; ZINNER Hydroxylamine Synthesis; ZVILICHOVSKY Heterocycle Synthesis

Organic Syntheses Based on Named Reactions is an indispensable reference companion for chemistry students and researchers. Building on Hassner & Stumer's highly regarded 2e, this new work reviews 750 reactions, with over 100 new stereoselective and regioselective reactions. Each A-Z entry provides a carefully condensed summary of valuable information that a chemist needs to understand and utilize these fundamental reactions in their work, including brief practical details. The book is illustrated with real synthetic examples from the literature and about 3,400 references to the primary literature to aid further reading. Extensive indexes (name, reagent, reaction) and a very useful functional group transformation index help the reader fully navigate this extensive collection of important reactions. With its comprehensive coverage, superb organization and quality of presentation, this long-awaited new edition belongs on the shelf of every organic chemist. * Handy reference guide that explains 750 established named processes and methods that are trusted and used by organic chemists to synthesize or transform molecules* Provides key data on each transformation including background, mechanism and--uniquely to books in this area--experimental details* Extensive and multiple indexes allow the reader to search for information as and how they want and to rapidly plan transformations

This article contains brief overviews, mechanisms and practical details for organic synthesis named reactions and processes beginning with the letter ‘P’. Reactions included in this section are: PAAL–KNORR Pyrrole Synthesis; PADWA Pyrroline Synthesis; PARHAM Cyclization via Lithiation of Aryl Bromides; PARNES Methyl Transfer; PASSERINI Isonitrile C O Condensation; PASTO–MATTESON α-Bromoorganoborane Rearrangement; PATERNO–BUCHI [2 + 2] Cycloaddition; PAUSON–KHAND Cyclopentenone Annulation; PAYNE Epoxide Rearrangement; von PECHMAN–DUISBERG Coumarin Synthesis; von PECHMAN Diazo-olefin Cycloaddition; PEARLMAN Pd Hydrogenolysis Catalyst; PEDERSEN Crown Ethers; PEDERSEN Niobium Coupling Reagents; PERKIN Carboxylic Acids (Esters) from Malonates; PERKIN Coumarin Rearrangement; PERKOW Vinyl Phosphate Synthesis; PETASIS 3-Component Amine Synthesis; PETASIS Titanocene Carbene Olefination; PETERSON Olefination via β-Silyl Alcohol; PFALTZ—EVANS Chiral Bis-oxazolines; PFAU – PLATTNER Cyclopropane Synthesis; PFITZINGER Quinoline Synthesis; PFITZNER–MOFFAT Alcohol Oxidation; PICTET–HUBERT Phenanthridine Synthesis; PICTET–SPENGLER Isoquinoline Synthesis; PILLOTY–ROBINSON Indole Synthesis; PINHEY Arylation; PINNER lmino Ether Synthesis; PINNICK Aldehyde Oxidation; PIRKLE Alcohol Resolution; POLONOVSKY N -Oxide Rearrangement; POMERANZ–FRITSCH–SCHLITTER Isoquinoline Synthesis; POSNER Trioxane Synthesis; PRELOG–STOLL Acyloin Condensation; PREVOST–WOODWARD Olefin Hydroxylation; PRILEJAEV Epoxidation; PRINS Alkene Hydroxyalkylation; PSCHORR Arylation via Diazonium Salts; PUDOVIK Hydroxy Phosphonate Synthesis; PUMMERER Sulfoxide Rearrangement; PURDIE Sugar OH Methylation

This article contains brief overviews, mechanisms and practical details for organic synthesis named reactions and processes beginning with the letter ‘J’. Reactions included in this section are: JACOBSEN Asymmetric Epoxidation; JAPP Oxazole Synthesis; JAPP–KLINGEMANN Hydrazone Synthesis; JEGER Free Radical Tetrahydrofuran Synthesis; JOHNSON Phenol Alkynylation; JOHNSON–CLAISEN Allyl Orthoester Rearrangement; JONES Cr Oxidizing Reagent; JULIA–COLONNA Asymmetric Epoxidation; JULIA – BRUYLANTS Cyclopropyl Carbinol Rearrangement; JULIA–KOCIENSKI One-Pot Olefination via Sulfone; JULIA–LYTHGOE Olefination via Sulfone; JUNG–OLAH–VORONKOV Ether Cleavage

This article contains brief overviews, mechanisms and practical details for organic synthesis named reactions and processes beginning with the letter ‘C’. Reactions included in this section are: CADOGAN Nitroaromatics Cyclization; CAGLIOTI Reductive Elimination of C O; CAMPS Quinoline Synthesis; CANNIZZARO Oxidation–Reduction; CARGILL Cyclobutenyl Ketone Rearrangement; CARROLL Allyl β-Ketoester Rearrangement; CELLA–PIANCATELLI Alcohol Oxidation; CHAN Acyloxyacetic Ester Rearrangement; CHAN–BRASSARD Aldol of Siloxydienes; CHAPMAN O-Aryliminoether Rearrangement; CHATGILALOGLU Silane Reducing Agent; CHICHIBABIN Arylpyridine Synthesis; CHICHIBABIN N-Heterocycle Amination; CHICHIBABIN Indolizine Synthesis; CHUGAEV Xanthate Elimination; CIAMICIAN C O Photocoupling; CIAMICIAN–DENNSTEDT Cyclopropanation; CLAISEN Allyl Vinyl Ether Rearrangement; CLAISEN Ester=Ester Condensation; CLAUSON–KAAS Pyrrole Synthesis; CLAY–KINNEAR–PERREN Phosphonyl Chloride Synthesis; CLEMMENSEN C O Reduction; CLIVE–REICH–SHARPLESS Olefination via Selenides; CLOKE–WILSON Cyclopropyl Ketone Rearrangement; COLLMAN Carbonylation Reagent; COLVIN Alkyne Synthesis; COMBES Quinoline Synthesis; COMINS Triflating Reagent; CONCELLON Z -Olefin Synthesis; CONIA Ene Cyclization; COOPER–FINKBEINER Hydromagnesiation; COPE 1,5-Diene Rearrangement; COPE Olefin via N-Oxide Elimination; COREY Enantioselective Borane Reducing Agent; COREY Homologative Epoxidation; COREY Cr Oxidizing Reagents; COREY–CHAN Stereoselective Alkene Synthesis; COREY–FUCHS Alkyne Synthesis; COREY–KIM Oxidizing Reagent; COREY–NICOLAOU–GERLACH Macrolactonization; COREY–WINTER Olefins from Diols; CORNFORTH Oxazole Rearrangement; CRABBE Allene Synthesis; CRABTREE Directed Hydrogenation Catalyst; CRIEGEE Glycol Oxidation; CRIEGEE Hydroperoxide Rearrangement; CRIMMINS–HEATHCOCK Chiral Anti (Syn) Aldols; CRISTOL–FIRTH Halodecarboxylation; CURCI–MURRAY Dioxirane Reagents; CURTIUS Acyl Azide Rearrangement