A case of papillary cystic tumor (PCT) of the pancreas in a 40‐yr‐old woman is reported. This rare neoplasm was discovered fortuitously by a CT‐scan examination for a palpable abdominal uterine leiomyoma. Percutaneous fine‐needle aspiration (FNA) of the pancreatic mass was performed under CT‐scan guidance. Cytologic examination of the material gave the diagnosis of PCT, which was confirmed by histologic examination of the resected tumor. Immunohistochemical staining showed a high degree of positivity to wide‐spectrum anticytokeratin and anticytokeratin 20, and a weak positivity to anti‐NSE antibody. In addition, the tumor cells were highly reactive for progesterone antibody, while they were negative for estrogen. These findings suggest a ductal origin for PCT, and also suggest that sex hormones may play a role in its growth, but not in its genesis. We emphasize the value of FNA cytologic features in the diagnosis of these rare tumors. Diagn Cytopathol 1996;15:398–402. © 1996 Wiley‐Liss, Inc.
Sertoliform endometrioid carcinoma (SEC) is a rare ovarian neoplasm occurring almost exclusively in post-menopausal patients. We studied a 71-year-old patient who underwent a total hysterectomy with bilateral salpingo-oophorectomy for a right ovarian mass measuring 25 cm in its maximal dimension. Histology revealed an SEC, featuring foci of typical endometrioid carcinoma and areas of clear cell differentiation. This particular type of ovarian neoplasm, already described in 21 reported cases in the literature, must be distinguished from Sertoli cell tumours and Sertoli-Leydig cell tumours which are encountered at a younger age. We discuss the elements of the differential diagnosis and insist upon the value of anti-epithelial membrane antigen in identifying an SEC.