Background: New cases of HIV/AIDS are still being reported and threaten the achievement of the HIV-1 elimination goal in Burkina Faso. An adequate assessment of the extent of this problem is key to redistributing available resources. HIV-1 incidence and associated risk factors among pregnant women estimated in Burkina Faso. Materials and Methods: We conducted a cross-sectional survey of pregnant women in all 13 administrative regions of Burkina Faso from 2012 to 2016. Collected sera analyzed by Vironostika HIV Uniform II Plus O, ImmunoComb II HIV-1 & 2 Bispot, HIV BLOT 2.2 assays to determine serological status. HIV-1 LAg-Avidity EIA performed on HIV-1 positive samples to differentiate between recent and old infections. Sociodemographic information collected for all participants. Data analysis performed using EPI Info and XLSTAT. Results: A total of 36,848 pregnant women included in the analyses. Serological testing showed 483 HIV-1 positive, 18 HIV-2 positive, 7 HIV-1 + 2 coinfection cases. Overall, 355 HIV-1 positive samples tested with HIV-1 LAg-Avidity EIA; the remaining samples had insufficient volume to be tested. The adjusted incidence rates were 0.17% and 0.09% (p=0.0919) in 2015 and 2016, respectively. Sociodemographic factors associated with recent infections included the 25-34 and ≥35 year age groups, high education level, household and secretary occupations, trader wife, civil servant wife, residence in urban sites, being married, a length of stay in the administrative region of <1 year. Conclusion: HIV-1 incidence is decreasing in Burkina Faso. However, women with certain risk factors should be targeted in prevention programs to reach the country’s HIV-1 elimination goal.

Purpose of the study: To determine the socio-demographic factors influencing the dynamics of HIV prevalence among pregnant women in Burkina Faso.Material and methods: A total of 66,597 pregnant women from the 13 health regions of Burkina Faso were included in this study conducted between 2006 and 2014. Venous blood samples were collected and analyzed for the detection of HIV antibodies according to WHO / UNAIDS strategy II, using the mixed test Vironostika HIV Uniform II Plus O (Bio-Mérieux) and the test discriminating ImmunoCombII HIV-1 & 2 BiSpot (Orgenics). Samples with discordant results between the two tests, as well as those positive to HIV-2 or HIV-1 + 2, were retested with HIV BLOT 2.2 (MP Diagnostics). Sociodemographic data collected from the participants were correlated with their HIV status to determine key risk factors influencing HIV infection prevalence in Burkina Faso.Results: Sociodemographic data showed that the study population consisted mainly of married women (91.2%) at their first pregnancy (27.1%) with a large majority of them being housewives (86.2%) who did not attend any form of schooling (69.4%). About 88.4% had stayed longer than a year in the health region where they initially participated in the study and 55.8% were between 20 and 29 years of age. Overall HIV prevalence significantly dropped from 2.7 % in 2006 to 1.3% in 2014. However HIV seroprevalence in this study has varied significantly according to socio-demographic characteristics including marital status, parity, occupation, education, age group and the length of stay in the women's health community (p <0.0001). Factors sustaining HIV transmission included the status of being unmarried (OR=1.67 [1.42-1.97]), primigest (OR=1.64 [1.41-1.89]), having other occupations except being student (OR = 1.68 [1.20-2.33]), aged between 20-49 years (OR=3.14 [2.51-3.93]) and the duration of stay less than a year in their locality (OR=5.33 [4.61-10.16]) and these factors were identified as main risk factors associated with HIV prevalence.Conclusion: Burkina Faso remains among the countries with concentrated epidemics despite a significant reduction in the prevalence observed in this study. The inclusion of identified risk factors in the national HIV program could improve the quality of the response to the epidemic.Keywords: HIV-Pregnant Women-Risk Factors-Burkina Faso

Disclosure of HIV-serostatus remains a way to avoid sexual transmission of HIV because it allows partners to take the necessary protective measures, e. g. use of condoms. Disclosure is nevertheless difficult due to the discrimination associated with HIV. The objective of this study was to analyze factors leading to self-disclosure of HIV-positive status within a sample of persons of both sexes attending different healthcare services in Burkina Faso.Methodology. - Cross-sectional study conducted by interviewing 740 patients in 26 healthcare services. Univariate (Chi(2) test) and multivariate (logistic regression) analyses were performed. The significance level was 5%. Qualitative data on factors associated with self-disclosure of HIV-positive status were analyzed.Results. - The majority of the patients (81.4%) informed at least one person who was very often a close relative (descendant, ascendant and sibling) or the partner. At multivariate analysis, HIV-serostatus was associated with using antiretroviral treatment, (OR = 0.40, 95% CI: 0.3-0.7, P < 0.001), known HIV-serostatus for at least one year (OR = 0.6; 95% CI: 0.4-0.9), living in couple (2.3; 95% CI: 1.4-3.8).Conclusion. - In a context limiting HIV testing due to the fear of social stigma, these results appear to be in favor of the Voluntary Counseling Testing model with a focus on the couple and/or families. (C) 2012 Elsevier Masson SAS. All rights reserved.

Objectives: To assess the perception of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), and attitudes and practices towards highly active antiretroviral treatment (HAART) among patients living in a resource-poor region of northern Burkina Faso, where HAART has only become available in recent years.Study design: A clinic-based cross-sectional survey of 306 patients taking HAART and 106 patients not yet on HAART.Methods: Face-to-face interview with a structured questionnaire at the clinic or at participants' homes.Results: Most patients were illiterate, but overall, they had adequate knowledge and positive attitudes towards HAART, and self-reported that their adherence was good. However, AIDS carried a psychological burden, as 27% of respondents were concerned that others might discover they were on HAART. The majority of respondents expressed concerns about transmitting HIV to others, but only 22% had disclosed their HIV status to their partners, and condom use was suboptimal. Approximately one-third of participants in the HAART group reported that they could no longer work in the same way as before they had AIDS. Multivariate logistic regression found that education and living with someone were positively associated witha favourable functioning status, and distance from clinic and lack of general support from family or friends were negatively associated with a favourable functioning status.Conclusions: HAART was well accepted in this resource-poor region. Community education and supportive approaches may be critical for an effective preventive programme. (C) 2011 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.