Importance Day-of-surgery hyperglycaemia is a modifiable risk factor for adverse patient outcomes including infection and 30-day mortality. Despite these risks, important quality gaps in day-of-surgery glycaemic management have been demonstrated in multiple settings.Objective To describe barriers and facilitators to high-quality glycaemic management from the perspective of anaesthesiologists.Design This qualitative study was designed using two implementation frameworks, the Theoretical Domains Framework (TDF) and the Consolidated Framework for Implementation Research (CFIR), to understand individual and organisational drivers and barriers to high-quality glycaemic management by anaesthesiologists. A patient partner with type 1 diabetes mellitus who had undergone surgery in our setting participated in study design and analysis.Setting Four academic hospitals within a single provincial (Alberta) healthcare system in Canada.Participants Anaesthesiologists practising at any academically affiliated hospital in Edmonton or Calgary, Alberta, Canada.Interventions One-on-one semi-structured interviews exploring day-of-surgery glycaemic management.Main outcome and measures Deductive thematic analysis of one-on-one interviews with anaesthesiologists was based on the TDF and CFIR.Results Saturation was reached after 13 interviews. There was important between-provider variation within the TDF constructs of memory, attention and decision-making processes and goals. Anaesthesiologists differed in whether they postponed surgery based on glycaemic status, whether they administered dexamethasone for postoperative nausea and vomiting prophylaxis for patients with diabetes, and in their definition of hyperglycaemia. Participants attributed this variation to patient and surgical factors, low knowledge of existing guidelines and lack of skills to select a dose of insulin. This variation in perioperative glycaemic management and treatment of hyperglycaemia is likely an important contributor to observed day-of-surgery glycaemic management quality gaps.Conclusions and relevance Quality improvement interventions meant to improve day-of-surgery glycaemic management should address between-anaesthesiologist variation in glycaemic management processes and targets.
Background Perioperative and diabetes guidelines recommend measurement of glucose and treatment of hyperglycemia in patients with diabetes on the day of surgery to reduce adverse events. However, between 15–30% of people with diabetes have inadequate glycemic management on the day of surgery. Objective This manuscript describes teamwork barriers to day-of-surgery glucose management identified during a larger study of barriers to high-quality perioperative glycemic management. Methods Anesthesiologists and perioperative nurses working at 8 hospitals in a single healthcare system (Alberta, Canada) were invited to participant in semi-structured interviews about their perceptions of perioperative glycemic management. Interview guides and deductive thematic analysis were informed by two implementation frameworks used to study barriers and facilitators of behaviours in healthcare: the Consolidated Framework for Implementation Research (CFIR) and Theoretical Domains Framework (TDF). Results There were 24 participants (13 anesthesiologists and 11 nurses). Lack of clear roles and responsibilities, lack of coordination between providers and settings, and lack of shared and valued goals were the most common teamwork gaps. Anesthesiologists and nurses provided conflicting answers about which healthcare provider can or should enter orders for glycemic management. Despite many anesthesiologists reporting target glucose values less than 10 to 14 mmol/L, most nurses shared that anesthesiologists did not typically treat hyperglycemia on the day-of-surgery until values were much higher. Conclusions Improving the quality of day-of-surgery glycemic management should target local barriers. In complex, multidisciplinary medical settings, quality improvement teams should address teamwork barriers in addition to barriers identified through traditional implementation frameworks like CFIR and TDF.
Intraoperative hyperglycemia is associated with adverse patient outcomes and there are major quality gaps in intraoperative glucose measurement and management. It is unclear how anesthesiologists can accurately and feasibly measure glucose values during surgery. Our purpose in this systematic review was to describe the current literature describing the precision and accuracy of intraoperative glucose measurement to inform clinical decision-making for anaesthesiologists. A systematic search strategy identified English-language studies that compared 2 or more methods to measure a blood glucose value during surgery for adult, nonpregnant patients. MEDLINE, PubMed, Embase, and CINAHL were searched from inception until 2024. A grey literature search and hand searching of reference lists for included articles was also completed. Abstracts and full text were screened and then extracted in duplicate by study team members. Of 8,691 unique studies identified, 23 studies were included in the analysis (1,258 total patients, 4,071 pairs of glucose measurements). There was important heterogeneity between these studies with respect to the blood source, blood fraction, comparator measurement method, reference measurement method, and statistical analysis used. This heterogeneity precluded meta-analysis of results. Hypoglycemia was rare (9 of 1,992 measurements, 0.45%). Most studies did not use international accuracy standards to determine whether differences between their comparator measurement method and reference measurement method were clinically acceptable. The optimal method to measure intraoperative glucose is not known. In the meantime, anesthesiologists should consider the characteristics of existing glucose measurement methods when selecting a method for their settings and patients.
Perioperative hyperglycemia is associated with worse patient outcomes. Characterizing quality gaps in day-of-surgery glucose management can guide quality improvement teams to address this risk factor for infection, readmission, and death. This retrospective cohort study used administrative and electronic health record data to describe process, outcome, and balancing measures of day-of-surgery glycemic management for adult patients with and without diabetes undergoing surgery at 6 hospitals in Alberta, Canada between 2019 and 2024. Participants were stratified by diabetes, prediabetes, no diabetes and unknown diabetes status. We report the association between hyperglycemia (blood glucose ≥ 10.0 mmol.L−1) and length of stay, admission to ICU, and 30-day readmissions as an exploratory analysis. There were 12,275 eligible procedures including 3,164 procedures performed on patients with diabetes (25.8
OBJECTIVE:With the development of novel antibody-drug conjugates (ADCs), folate receptor alpha (FOLR1) is a promising therapeutic target for the treatment of platinum-resistant tubo-ovarian carcinomas. The main aims of this study were to assess FOLR1 protein expression in a large cohort of ovarian carcinoma histotypes. To inform future clinical trial design we identified molecular correlates of FOLR1 expression in low-grade serous carcinoma (LGSC). METHODS:One thousand five hundred forty-seven ovarian carcinoma samples from 5 different Canadian cohorts were successfully evaluated by immunohistochemistry for FOLR1 expression using the PS2+ system. Statistical analyses with clinicopathological parameters, LGSC molecular subtypes, and overall survival (OS) were performed. RESULTS:High FOLR1 expression was detected in 44% of high-grade serous carcinomas, and in 30% LGSC, 8% clear cell, 6% endometrioid, and 0% mucinous and/or mesonephric-type adenocarcinomas. In 160 LGSC cases, FOLR1 expression was more frequent in cases with normal MAPK pathway status (37% MAPK wild type vs. 14% canonical MAPK pathway mutations; p=0.002), low progesterone receptor (PR) expression (41%) vs. 23% (Allred score >2; p=0.02), and p16 loss (48% p16 absent vs. 26% normal; p=0.03). Canonical MAPK mutation status and PR expression remained significant on multivariable analysis. No significant associations between OS and FOLR1 expression were observed. CONCLUSION:A significant proportion of LGSC express high FOLR1 levels supporting the development of clinical trials to investigate ADCs targeting FOLR1 as novel agents for treating this disease. In LGSC, high FOLR1 expression was associated with fewer MAPK pathway alterations, low PR expression, and p16 loss.
OBJECTIVE:To assess the management and outcomes of patients diagnosed with an isolated serous tubal intraepithelial carcinoma lesion across Canada. METHODS:This retrospective study included consecutive patients with an isolated serous tubal intraepithelial carcinoma lesion diagnosed between 2006 and 2020 at 15 Canadian centers. Cases underwent multicenter panel pathology review. RESULTS:Of 107 patients, 41 serous tubal intraepithelial carcinoma cases (38.3%) were identified at prophylactic surgery for germline pathogenic variants, 36 (33.6%) at surgery for suspicion of malignancy, and 30 (28.0%) at surgery for benign conditions. Treatment groups included observation (n=62, 57.9%), staging surgery (n=35, 32.7%), and adjuvant chemotherapy (n=10, 9.3%). Median follow-up was 55.5 months (interquartile range 30.26-82.07 months). Overall, nine patients developed high-grade serous carcinoma. The cumulative incidence of high-grade serous carcinoma was not significantly different between treatment groups ( P =.181); however, no patient treated with chemotherapy developed high-grade serous carcinoma. The cumulative incidence of high-grade serous carcinoma was 1.1% (95% CI, 0.1-5.3%) at 2 years and 5.7% (95% CI, 1.8-13.1%) at 5 years. No significant predictive factors were found on univariate analysis. After multicenter pathology review of 59 cases (55.1%), consensus diagnosis was reached: 45 (76.3%) with serous tubal intraepithelial carcinoma, three (5.1%) with serous tubal intraepithelial lesion, seven (11.9%) with high-grade serous carcinoma, and two (3.4%) with normal tissue. Of the cases reviewed, only 1 of 45 patients (2.2%) with confirmed serous tubal intraepithelial carcinoma developed high-grade serous carcinoma at 73 months, indicating a 5-year cumulative incidence of cancer of 2.6% (95% CI, 0.2-11.7). CONCLUSION:Management of serous tubal intraepithelial carcinoma varied across centers. The 5-year cumulative incidence of high-grade serous carcinoma after isolated serous tubal intraepithelial carcinoma was 5.7%, consistent with recent literature. However, multicenter pathology review revealed initial underdiagnosed high-grade serous carcinoma, and 5-year cumulative incidence of high-grade serous carcinoma after confirmed serous tubal intraepithelial carcinoma decreased to 2.6%, underscoring the importance of diagnostic confirmation by expert pathologists to guide accurate management.
Low-grade serous carcinoma (LGSC) is an uncommon histotype of ovarian carcinoma, accounting for ~3% of cases. There is evidence that survival of peritoneal LGSC (pLGSC) is longer than that of ovarian LGSC (oLGSC). Key molecular alterations of LGSC have been established, including loss of CDKN2A and PR expression, MAPK pathway alterations, and loss of USP9X expression. We hypothesized that LGSC could be subclassified into clinically applicable molecular subtypes by a few surrogate tests similar to endometrioid carcinomas using a hierarchical decision tree based on the strength of the prognostic associations of the individual alterations. Our study included 71 LGSCs. Immunohistochemistry for CDKN2A, ER, PR, NF1, and USP9X and sequencing for KRAS, NRAS, and BRAF were performed. Our data showed the co-occurrence of key molecular alterations, and despite suggestive trends, hierarchical molecular subtyping did not provide significantly different stratification of patients according to survival in this cohort. We confirmed that patients diagnosed with pLGSC have a longer survival than high-stage oLGSC, with the intriguing observation that normal CDKN2A and PR status were associated with excellent survival in pLGSC. Therefore, CDKN2A and PR status might aid in the classification of indeterminate implants, where abnormal findings favor pLGSC over noninvasive implants. Molecular subtypes should be further evaluated in larger cohorts for their prognostic and potentially predictive value.
Objective. To evaluate the clinical outcomes pre- and post -implementation of an evidence -informed surgical site infection prevention bundle (SSIPB) in gynecologic oncology patients within an Enhanced Recovery After Surgery (ERAS) care pathway. Methods. Patients undergoing laparotomy for a gynecologic oncology surgery between January -June 2017 (pre-SSIPB) and between January 2018 -December 2020 (post-SSIPB) were compared using t -tests and chisquare. Patient characteristics, surgical factors, and ERAS process measures and outcomes were abstracted from the ERAS (R) Interactive Audit System (EIAS). The primary outcomes were incidence of surgical site infections (SSI) during post -operative hospital admission and at 30 -days post -surgery. Secondary outcomes included total postoperative infections, length of stay, and any surgical complications. Multivariate models were used to adjust for potential confounding factors. Results. Patient and surgical characteristics were similar in the pre- and post -implementation periods. Evaluation of implementation suggested that preoperative and intraoperative components of the intervention were most consistently used. Infectious complications within 30 days of surgery decreased from 42.1% to 24.4% after implementation of the SSIPB ( p < 0.001), including reductions in wound infections (17.0% to 10.8%, p = 0.02), urinary tract infections (UTI) (12.7% to 4.5%, p < 0.001), and intra-abdominal abscesses (5.4% to 2.5%, p = 0.05). These reductions were associated with a decrease in median length of stay from 3 to 2 days ( p = 0.001). In multivariate analysis, these SSI reductions remained statistically signi ficant after adjustment for potential confounders. Conclusion. Implementation of SSIPB was associated with a reduction in SSIs and infectious complications, as well as a shorter length of stay in gynecologic oncology patients. (c) 2024 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC license (http:// creativecommons.org/licenses/by-nc/4.0/).
Au moyen de données sur les déclarations fiscales individuelles, les autrices ont simulé des revenus de base garantis au Nunavut. Elles ont déterminé le revenu de base réalisable en fonction du budget du Nunavut, qui permettrait de réduire le plus la pauvreté au moindre coût. Elles ont établi que le Nunavut pourrait adopter un modeste revenu de base à l'aide des « économies » réalisées grâce à l’élimination des crédits d'impôt et de l'aide au revenu. Étant donné la faible assiette fiscale du Nunavut, un revenu de base plus généreux exigerait un financement fédéral. Ainsi, un revenu de base pourrait atténuer des préoccupations comme l'insécurité alimentaire, mais n’éliminerait pas la nécessité de programmes comme l'aide au logement ni ne couvrirait la totalité des coûts liés aux récoltes. En vertu du programme actuel d'aide au revenu du Nunavut, les bénéficiaires doivent participer à des « choix productifs ». Il serait difficile de mettre en œuvre des conditions semblables, souvent intégrées au revenu de base des Autochtones, si un tel revenu était administré par le régime fiscal. Les chercheurs explorent ces questions et d'autres aspects dans le contexte des principes inuits.
This article traces the theoretical foundations, evolution and limitations of Gender-Based Analysis Plus (GBA+), which, twenty-five years after its conception, remains the federal government's primary mechanism for attending to issues of equality and diversity in public policy. In line with recent scholarship, we argue that GBA+, as operationalized in the federal bureaucracy, is insufficient as a framework for intersectional policy analysis, not least due to a weak expression of core principles of intersectionality. Seeking to both elucidate and make more prominent within GBA+ its theoretical underpinnings, as well as nudge shifts in how the framework is applied over the course of the policy process, we draw on critical feminist and intersectional methods to adapt the GBA+ tool. By applying key elements of the adapted framework to examine basic income, a policy proposal that has gained favour in recent years as a transformative solution to poverty and inequality, we highlight how a strengthened GBA+ approach that embraces critical feminist and intersectional analysis—or indeed a shift to a more explicitly intersectional framework—can expand and enrich the ways we think about the potential and limitations of policies in the context of creating a more just society.
Objective: We evaluated implementation and clinical outcomes of a perioperative glycemic management pathway in gynecologic oncology. Methods: Interrupted time-series analysis was used to compare process, balancing and outcome mea-sures and clinical outcomes from 18 months preimplementation to 18 months postimplementation. Results: Compared with in the preimplementation period, the proportion of patients who underwent preoperative screening with glycated hemoglobin in the postimplementation period increased by 11.3% (95% confidence interval [CI], 5.0% to 17.7%; p=0.001). The proportion of patients with diabetes who had at least 1 blood glucose measurement after surgery increased by 15.3% (95% CI,-3.2% to 33.8%; p=0.10). There was no change in the proportion of patients who had any hyperglycemia or moderate or severe hyperglycemia. The median length of stay decreased by 0.42 days (95% CI,-0.91 to 0.07 days; p=0.09). There were major quality gaps in perioperative glycemic management that did not clearly improve after implementation of a multidisciplinary care pathway. Conclusion: Optimal strategies for improvement of perioperative glycemic management are not yet known. (c) 2022 Canadian Diabetes Association.
The National Action Plan to end Gender-Based Violence, which recently received official endorsement by the Federal, Provincial, and Territorial Ministers responsible for the Status of Women, identifies a key role for economic security policy. Specifically, the Social Infrastructure and Enabling Environment pillar acknowledges that an expansion of social programs and supports is vital if we are to reduce the socio-economic inequalities that undergird GBV risk and prevalence for diverse women, girls, and non-binary people, while the Support for Victims, Survivors, and Their Families pillar indicates a commitment to investing in and extending access to effective supports and services, including emergency financial assistance, to ensure people impacted by violence can make a safe exit and recovery.Envisioned in response to the need to better understand how economic security policies can factor into this picture most effectively, this knowledge synthesis presents a review of the existing evidence on cash transfers and intimate partner violence—one of the most prevalent forms of gender-based violence—with the aim of contributing insight on a number of key questions. In particular, we examined the interconnections between economic security and intimate partner violence to uncover the manifold links and intersections between the two concepts; reviewed through a layered assessment of the academic and grey literature the state of the evidence on the role of cash transfers (and economic security policies more broadly) both in preventing and/or reducing IPV, as well as in supporting exit; and also considered key design and implementation elements important in the context of violence and its many consequences. The findings of this synthesis report can be considered along two key dimensions.
Objective: Our aim in this study was to identify the barriers to following recommendations for post-operative glycemic management among surgical team members. Methods: We conducted semistructured interviews with surgical team members guided by 2 theoretical frameworks for understanding the barriers and drivers of health-care behaviours: the Theoretical Domains Framework and the Consolidated Framework for Implementation Research. Interview data were coded deductively by 2 study team members. Results: Sixteen surgical team members from 7 surgical disciplines at a single hospital participated in this investigation. The most important barriers to management of postoperative hyperglycemia were knowledge of glycemic targets, belief about consequences of hyper-and hypoglycemia, available resources to manage hyperglycemia, adaptability of usual insulin regimens to complex postoperative patients, and skills to initiate insulin. Conclusions: Interventions to reduce postoperative hyperglycemia are unlikely to be effective unless they use implementation science to address local barriers to high-quality management among surgical team members, including setting and systems-level barriers.O 2023 Canadian Diabetes Association.
Canada’s short-term rental (STR) market has grown considerably in recent years, resulting in a heightened focus by local governments on adopting regulatory approaches to manage it. Indeed, since 2018, an increasing number of Canadian governments (largely cities) have introduced regulatory frameworks to both mitigate perceived negative impacts of the STR market, as well as reap some of its benefits. In light of the gap in Canada-focused research on STR regulation, this article analyzes in comparative perspective the regulatory approaches adopted in 11 Canadian jurisdictions in response to the rise of platform-mediated home sharing. We find that aspects of regulation, such as licensing and registration, are increasingly a question, not of “if,” but rather “how” and “to what extent,” with the most promising approaches being those that reflect sophisticated understandings of the range of activity that plays out in the market and the various actors, including platforms and property managers, involved. For jurisdictions looking to introduce or tweak approaches going forward, there is potential benefit in reframing market regulation as a governance issue, rather than a technical legal problem. From this standpoint, of particular promise are joint governance approaches which involve municipalities and other local jurisdictions implementing distinct rules within the context of an overarching provincial framework.
Objectives Postoperative hyperglycemia occurs in two-thirds of non-cardiac surgery patients and is associated with increased morbidity and mortality. We implemented a multi-disciplinary perioperative glycemic management pathway with the aim of reducing postoperative hyperglycemia and improving patient outcomes. Methods Our study evaluated the implementation of the PGMP in gynecologic oncology patients. The PGMP encompasses glycemic management across the outpatient and inpatient surgical journey. We report changes in process measures (blood glucose measurement), outcome measures (hyperglycemia) and clinical measures (length-of-stay) pre- and post-implementation. Single-cohort interrupted time-series analysis was used to compare pre- (April 1, 2018 – September 30, 2019) and post- (October 1, 2019 – March 31, 2021) intervention means and trends. Results 949 gynecologic oncology patients were evaluated pre-intervention, and 878 post. After implementation, the proportion of patients who were screened with HbA1c increased by 11.3% (95% CI: 5.0, 17.7%; p=0.02). The proportion of patients with diabetes who had at least one blood glucose measurement in the first 24-hours after surgery increased by 15.3% (95% CI: -3.2, 33.8%; p=0.10). Median length-of-stay for all postoperative patients decreased by 0.42 days (95% CI: -0.91, 0.07 days; p=0.09). There was no change in 30-day readmissions, regardless of diabetes diagnosis. Conclusions Implementation of PGMP increased the identification of patients at high-risk for hyperglycemia. Our pilot reveals challenges experienced in evaluating perioperative glycemic management. Our study also showcases the need to measure both process and outcome measures and the need to perform robust statistical analysis when evaluating quality improvement initiatives.
Objectives Frailty is associated with adverse outcomes in the oncologic and surgical patient. Frailty indices have been developed in multiple surgical fields and have been found to be predictive of post-operative morbidity and mortality. We aim to validate the Modified Frailty Index amongst our patient population. We hypothesize that those with increased frailty are at increased risk of surgical morbidity and mortality and that identifying these patients and applying Quality Improvement (QI) designed interventions may reduce adverse outcomes. Methods New patients who presented to the Gynaecologic Oncology service in Calgary, Alberta completed a frailty index. Between January 2020 and May 2021, frailty indices were collected on 616 patients, of which 475 underwent surgery. Frailty scores were compared to the primary outcome measures including: length-of-stay, 30-day morbidity, re-admission, and mortality. Thirty-day morbidity was assessed with the Clavien-Dindo classification. Secondary outcome measures include: documented residual disease, consultations within hospital, and non-home discharge. Data regarding patients' baseline characteristics, malignancy, and surgery were also documented. Results Baseline analysis show frail patients are more likely to experience post-surgical complications and to have a longer length-of-stay (p = 0.018 for both). There is a trend towards an increased frequency of readmissions (p = 0.052). Sub-group analysis reveal a higher grade of complications based on Clavien-Dindo classification for frail endometrial cancer patients (p = 0.022). Conclusions Preliminary analysis reveal the Modified Frailty Index is predictive of increased risk of post-surgical morbidity and complications in our population. Further application of the index and interventions may assist in surgical decision-making and improving post-operative outcomes.
ABSTRACTPeople with diabetes are at an increased risk for worse postoperative outcomes, compared to people without diabetes. Notably, up to one in 10 people who undergo surgery have unrecognized diabetes and an additional 10% may have postoperative hyperglycemia without meeting the criteria for a diagnosis of diabetes. Management of postoperative hyperglycemia has been demonstrated to reduce the incidence of poor outcomes, but evidence demonstrates that postoperative hyperglycemia remains a quality gap for surgical patients. In this review, we will outline the evidence for preoperative screening for postoperative hyperglycemic risk, review the evidence for perioperative glycemic management, and examine the barriers to these best practices. RÉSUMÉLes personnes atteintes de diabète courent un risque accru de voir leurs résultats postopératoires moins bons que ceux des personne non atteinte de diabète. En particulier, près d’une personne sur dix qui subit une intervention chirurgicale présente un diabète non diagnostiqué et dix pour cent supplémentaires peuvent présenter une hyperglycémie postopératoire sans pour autant répondre aux critères de diagnostic du diabète. Il a été démontré que le traitement de l’hyperglycémie postopératoire réduit l’incidence des mauvais résultats, mais les données probantes montrent que l’hyperglycémie postopératoire demeure une lacune chez les patients opérés. Dans cette revue, nous présentons les données probantes relatives au dépistage préopératoire du risque d’hyperglycémie postopératoire, nous passons en revue les données probantes relatives à la gestion de la glycémie périopératoire et nous examinons les obstacles à ces meilleures pratiques.
Introduction Evidence-based preoperative, intraoperative and postoperative glycemic management may reduce poor surgical outcomes. Previous studies suggest that quality gaps in perioperative glycemic management may be common. Research design and methods This retrospective cohort study used administrative health and laboratory data from a single center to estimate quality gaps in perioperative glycemic management in patients with and without diabetes between April 2019 and March 2020. We examined the proportion of patients with preoperative hemoglobin A1c (HbA1c) measurement, postoperative point-of-care testing (POCT) for glucose, hyperglycemia, and basal bolus insulin regimens. We compared the median length of stay (LOS) in patients with and without postoperative hyperglycemia, adjusted for age and sex. Results There were 6576 patients in our cohort; 1165 (17.8%) had diabetes. Most patients with diabetes had an HbA1c measured prior to surgery (n=697, 59.8%). Postoperatively, 16.9% of patients with diabetes had no POCT monitoring (n=197) and 65.7% had hyperglycemia (n=636). Only 35.9% of patients who received insulin had a basal bolus insulin regimen (n=229). Patients with diabetes who had postoperative hyperglycemia had a longer median LOS compared with those who did not have postoperative hyperglycemia (8.4 days (95% CI 7.5 to 9.4) and 6.7 days (95% CI 6.3 to 7.1), respectively). In patients without diabetes, median LOS was 7.4 days (95% CI 4.4 to 10.4) for those with hyperglycemia and 5.2 days (95% CI 5.1 to 5.4) for those with in-target glucose. Conclusions Quality gaps in perioperative glycemic management include measurement of blood glucose after surgery and treatment of postoperative hyperglycemia. These gaps may contribute to longer LOS.
In Canada, diverse people face violence and abuse at alarming rates as a result of their gender, perceived gender, or gender expression. This phenomenon is referred to as gender-based violence (GBV). Gender-based violence has many manifestations, including sexual assault, femicide, and intimate partner violence (IPV), as well as dowry-related violence, early or forced marriage and pregnancy, female genital mutilation, elder abuse, human trafficking, sexual harassment, cyber abuse, and many other forms, both visible and invisible. Crucially, GBV does not simply occur in the context of inter-personal relationships or as the result of perpetration by 'bad men'; rather, GBV is a systemic issue that seizes upon and operates through longstanding pathologies and power dynamics—patriarchy, racism, colonialism, and transphobia to name few—rendering diverse people more vulnerable to victimization on the basis of their identity. Strategies, policies, and programs focused on ensuring victims and survivors can achieve economic security will form a vital component of any serious plan to address GBV. On this point there is notable consensus. Less agreement exists, however, when debate begins on the question of which strategies, policies, and programs ought to be implemented. In this discussion paper, we weigh in on this debate through an evaluation of an economic security tool over which there has been much fanfare in recent years: the basic income model. Two questions guide our analysis: (1) to what extent could a basic income disrupt the material conditions and forms of oppression which drive GBV, and thus reduce both risk and prevalence? and (2) to what extent would basic income be an effective support for those encountering/recovering from various forms of GBV? Our analysis is driven by two definitional assumptions about economic security and basic income. That is, we consider economic security to be a state in which criteria for financial security, stability, and continuity are fulfilled, and conceive of basic income as a class of policies that share principles of simplicity, respect, economic security, and social inclusion.