To determine the barriers and facilitators to the implementation and scale-up of the Akoma Pa mHealth-based integrated care program for diabetes and hypertension in Ghana. 30 implementation managers and healthcare providers (Akoma Pa champions) were interviewed in-depth based on their experience and ability to provide information on implementing and scaling-up the Akoma Pa program in February 2024. Participants were selected from the Christian Health Association Ghana healthcare facilities across Ghana. Thematic qualitative content analysis based on Kuckartz was used to identify recurring themes and categories, guided by the mHealth Predisposing Characteristics, Needs, and Enabling Resources (PNE) Framework. Participants identified 47 factors influencing the implementation and scale-up of the intervention, categorized into provider- and patient-level contextual factors. Findings were organized according to perceived usefulness and perceived ease of use, reflecting assessments of value, feasibility, and scale-up potential. Key enablers included mobile phone accessibility, provider engagement, and integration with the National Health Insurance Scheme. Reported barriers included digital infrastructure gaps, policy misalignment, lack of data protection policies and workforce limitations. Although the SPICE app, central to the Akoma Pa digital health program, enhanced patient tracking and care coordination, it still required ongoing support to ensure interoperability and scalability. Evidence-based practices and personalized care improved patient management and outcomes. Integrated mHealth programs such as Akoma Pa hold promise for strengthening chronic disease management in low-resource settings. Addressing infrastructural and long-term funding barriers is critical to sustaining and scaling these interventions. Findings offer insights to inform future digital health policy and program design in sub-Saharan Africa.
Despite the achievements of the Ghana Health Service and its partners in reducing malaria morbidity and mortality in Ghana, the disease still poses a significant public health problem and a huge expenditure on the National Health Insurance Scheme and the economy. This review examined the strategies employed to control malaria in northern Ghana, explored the progress made, and discussed the challenges that persist. A literature search was conducted across four databases—Medline, Embase, Scopus, and Cochrane Library—to identify studies conducted in Northern Ghana on malaria control interventions between 1st January 2013 and 10th June 2023. The data were handled using Covidence; of the 1782 studies identified, 38 met the eligibility criteria and were included in this review. The data were analysed with MS Excel and presented in tables. Most of the studies (44.7
The objective of this study was to investigate the knowledge and techniques of teachers from basic schools in identifying and managing of children with special educational needs. The study adopted a cross-sectional descriptive research design. Sixty-five full-time teachers in Ghana (mean age of 35.04±9.05 years; mean work experience of 7.71 ±8.20 years) were recruited. Self-structured interview guide and questionnaire were used for data collection. Data analysis showed that 86.2% of the teachers reported being aware of educational and national policies for children with SEN in Ghana. Additionally, 93.9% indicated that they had received training and held responsibilities for identifying children with SEN in their classes. Regarding the methods used, 76.9% relied on referrals from parents, 75.4% on referrals from colleague teachers, and 70.8% on students’ academic progress reports. Moreover, 63.08% stated that “special attention” was the primary technique used in managing children with SEN. 86.15% agreed that “there are no resources, strategies, or interventions in schools that are particularly effective in supporting SEN children. As for support techniques, 84.6% reported collecting more detailed information from class teachers and conducting further assessments, 76.9% relied on information from parents, while 75.4% set targets for identifying children with SEN. Participants significantly conducted further assessments and arranged for assessments from other professionals as techniques of identifying children with SEN. Although the participants have a general understanding of how to identify and manage SEN children, they need more extensive exposure and practical experience in working with SEN children within the regular classroom environment.
BACKGROUND:The human immunodeficiency virus (HIV) has caused a lot of havoc since the early 1970s, affecting 37.6 million people worldwide. The 90-90-90 treatment policy was adopted in Ghana in 2015 with the overall aim to end new infections by 2030, and to improve the life expectancy of HIV seropositive individuals. With the scale-up of Highly Active Antiretroviral Therapy, the lifespan of People Living with HIV (PLWH) on antiretrovirals (ARVs) is expected to improve. In rural districts in Ghana, little is known about the survival probabilities of PLWH on ARVs. Hence, this study was conducted to estimate the survival trends of PLWH on ARVs. METHODS:A retrospective evaluation of data gathered across ARV centres within Tatale and Zabzugu districts in Ghana from 2016 to 2020 among PLWH on ARVs. A total of 261 participants were recruited for the study. The data was analyzed using STATA software version 16.0. Lifetable analysis and Kaplan-Meier graph were used to assess the survival probabilities. "Stptime" per 1000 person-years and the competing risk regression were used to evaluate mortality rates and risk. RESULTS:The cumulative survival probability was 0.8847 (95% CI: 0.8334-0.9209). The overall mortality rate was 51.89 (95% CI: 36.89-72.97) per 1000 person-years. WHO stage III and IV [AHR: 4.25 (95%CI: 1.6-9.71) p = 0.001] as well as age group (50+ years) [AHR: 5.02 (95% CI: 1.78-14.13) p = 0.002] were associated with mortality. CONCLUSION:Survival probabilities were high among the population of PLWH in Tatale and Zabzugu with declining mortality rates. Clinicians should provide critical attention and care to patients at HIV WHO stages III and IV and intensify HIV screening at all entry points since early diagnosis is associated with high survival probabilities.
Many hospitals that manage health emergencies are resource-constrained and as such have challenges to provide quality care to patients. Exploring these challenges in resource-constrained hospitals and addressing them at the operational level through coping mechanisms could aid timely interventions to save patients with potentially life-threatening conditions. The study adopted qualitative approach and grounded theory design. Simple random sampling was used to cluster selected hospitals while purposive sampling was used to select right cadre of nursing leaders with experience to provide needed information. Data collection was done through interviews. Findings indicate nursing staff face a myriad of challenges including logistics, human resources, knowledge, financial resources, staff attitude and professional barriers in managing critically-ill patients. The findings also indicate that, identified challenges have resulted in increased workload, job dissatisfaction among staff, and some negative consequences on the safety and health care outcomes of patients. The most important recommendation from the participants is increasing the availability of in-service emergency training to improve skill levels of nurses and patient outcomes.
Anemia is a public health problem that affects about 50% of adolescent females in sub-Saharan Africa. Anemia can negatively affect the overall growth, cognitive performance, and productivity of school-going adolescents. This pilot study assessed the impact of Solanum torvum-fortified biscuits on hemoglobin levels and cognitive performance of school-going adolescent females. A cluster randomized controlled, open labeled trial was undertaken among four basic schools in the Ahafo Region of Ghana. Out of the 169 participants, 151 (intervention=83, control=68) adolescent females completed the trial. The intervention and control groups were made up of two schools each. The participants in the intervention and control groups received a total of 30 turkey berry-fortified biscuit supplementation or 30 placebos for a period of six weeks, respectively. The hemoglobin levels and cognitive test scores were obtained before and after the intervention. The number of anemic cases and low cognitive performance among the female adolescents in the intervention group reduced by 23.8% and 8.7%, respectively. There was a positive impact on the hemoglobin levels and cognitive performance of the intervention group. For every unit of turkey berry-fortified biscuit consumed by the intervention group, there was a 0.945 unit increase in hemoglobin level (p=0.001) and a 2.796 unit increase in cognitive performance (p=0.005). The turkey berry-fortified biscuit significantly reduced anemia prevalence and improved cognitive performance among the adolescent girls. Therefore, its potential in the management of anemia and improvement of cognition could be explored.
Purpose The perceptions of disability conditions held by parents and immediate family members directly determine the types of treatments that are likely to opt for persons with disabilities whenever they are ill. Family level drivers of access to healthcare among persons with disabilities in the Bosomtwe district of Ghana. Design/methodology/approach A qualitative case study was conducted in which data were collected from 60 participants selected purposively. Face-to-face interviews were conducted, and the results were presented thematically. Findings The drivers identified have been categorized into positive and negative depending on how they influenced persons with disabilities’ access to health care. Payment of medical bills, physical access support, the narration of health condition to a health-care provider, spiritual support, care and love were the positives while perceived spiritual cause of disability, preference for alternative treatment centers, unwillingness to support reproductive and specialized health care. Research limitations/implications This study had some limitations, and one of such is the non-inclusion of disabled people who had not been registered by the department of social welfare but resided in the district who could have provided rich information to the study. However, their exclusion did not affect the quality of data obtained, as those who were registered and selected for the study gave adequate information about the issues that were considered during the study. Originality/value Family members of persons with disabilities play key roles in promoting their access to health care; therefore, there is the need for stakeholders to put in measures that will limit misconceptions about disability not only for the general public but also for individuals like parents and immediate family members of persons with disabilities.
AbstractAimThis study determined the prevalence and key determinants of burnout among nurses and midwives in Kumasi, Ghana.DesignHospital‐based cross‐sectional study.MethodA questionnaire was used to obtain data from 391 nurses and midwives at a tertiary hospital in Kumasi, Ghana using simple random sampling.ResultsAbout 84.4% of the participants were females. The majority of the study participants experienced low burnout for all dimensions (58% in emotional exhaustion, 55.5% poor personal accomplishment and 38.3% depersonalization). Multiple regression analysis revealed that high emotional exhaustion was independently predicted by post‐graduate education (β = 6.42, p = .003), lack of support from management (β = 2.07, p = .024), dislike for leadership style, (β = 3.54, p < .001) and inadequate number of staff (β = 2.93, p = .005). Age (β = 0.35, p = .004), lack of support from management (β = 1.60, p = .012), and inadequate number of staff (β = 1.49, p = .034) independently predicted high depersonalisation. Female sex (β = 4.36, p < .001) and years of practice (β = −0.26, p < .001) independently predicted low personal accomplishment.
Background. Burnout among nursing professionals at the workplace and how it influences their decision to quit the profession is crucial to the delivery of quality health service. The shortage of nursing professionals has serious consequences on the healthcare system. Aim. To examine the effect of burnout on intention to quit the profession among nursing professionals. Methods. A cross-sectional study among 375 randomly selected nursing professionals in active service at a tertiary healthcare setting in Kumasi, Ghana. The Maslach Burnout Inventory was used to determine burnout, and their intention to quit the profession was assessed by asking participants whether they ever thought about quitting the profession in the past 12 months. The effect of burnout on intention to quit was analyzed using logistic regression analysis. Results. The overall prevalence of burnout among participants was 2.1% (8/375) with 10.1% (38/375), 24.0% (90/375), and 56.3% (211/375) experiencing high emotional exhaustion, depersonalisation, and low personal accomplishment, respectively. Nearly half (49.3%, 185/375) of the participants had intention to quit the profession. Emotional exhaustion (adjusted odds tatio, AOR = 5.46; 95% CI = 2.25–13.20), depersonalisation (AOR = 1.77 95% CI = 1.07–2.95), and personal accomplishment (AOR = 2.27; 95% CI = 1.30–3.96) were associated with intention to quit the profession. Conclusion. Burnout has a negative effect causing intention to quit nursing profession. It is imperative to identify strategies such as occupational health surveillance that will aim at reducing the incidence of burnout at the workplace due to its consequences, one of them being the intention to quit.
Ghana is a lower-middle-income economy that has made significant efforts to improve its health system, in order to achieve universal health coverage. Ghana has adopted strategic health purchasing as an important tool for efficient utilization of resources. This paper focuses on Ghana's National Health Insurance Scheme (NHIS) analyzing its governance arrangements and purchasing functions; and providing recommendations for improvement. The study applied the Strategic Health Purchasing Progress Tracking Framework co-created by the Strategic Purchasing Africa Resource Center (SPARC) and its partners to collect data from secondary and primary sources between September 2019 and June 2020. A descriptive and narrative approach was used to synthesize information on the NHIS governance arrangements and purchasing functions based on the framework. Benchmarks were used to describe the NHIS on the continuum from passive to strategic purchasing and to identify steps to make purchasing more strategic. Strengths and weaknesses were found in governance and purchasing functions. Progress was seen in how the NHIS selects the services in the benefit package, regularly reviewing the package to respond to the health needs of the population, and in how it selectively contracts with providers, particularly private providers, to ensure that standards for quality of care are met. However, challenges remain in performance monitoring, due to claims being mostly processed manually, and provider payment, due to frequent unbundling and upcoding of services Ghana has made significant strides toward the achievement of universal health coverage, but there is room for improvement in provider payment and performance monitoring.
Malnutrition is a public health problem in Ghana, and is estimated to contribute indirectly to more than half of under-five deaths. This study was designed to describe how implementation of the Community-based Management of Malnutrition (CMAM) programme in Ghana differs in the rural and urban parts of the country. A mixed methods approach was used in a community-based survey that studied 497 mothers/caregivers and under-five pairs quantitatively, 25 health service providers qualitatively, and 25 mothers/caregivers qualitatively. Quantitative data were analysed descriptively with Stata 14.0 (Stata Corp, Texas, USA) while the qualitative data were analysed thematically with Atlas.ti, version 7.5 (Scientific Software Development GmbH, Berlin). Programme implementation was assessed using the following variables: availability of CMAM tools, availability of CMAM supplies, organization of out-patient therapeutic and supplementary feeding programmes, personnel availability, availability of community-based components of CMAM and maternal experience with CMAM services. While the number of children alive, provision of nutrition education and counselling, and demonstration of food preparation significantly influenced program effectiveness (p<0.05) in the urban site, no variables were found to do similar in the rural district. The rural facilities were more likely than the urban ones to be without tools. Less than 10% of mothers/caregivers in both study sites acknowledged the availability of the community-based components of CMAM. Programme implementation in the two study districts is poor; in order to ensure that the CMAM intervention translates into a reduced malnutrition burden among children under-five in Ghana, the programme implementation should be revised to address the identified shortcomings.
The health status and quality of life of disabled people are of immense public health concern and the Sustainable Development Goals cannot be achieved if the healthcare needs of disabled people are not met. A qualitative case study was conducted in the Bosomtwe District of Ghana to ascertain personal factors that affect disabled people's access to healthcare in the context of disability stigma. A total of 30 disabled participants were selected through purposive sampling, and data were collected through an interview guide utilizing a face-to-face interview and focus group discussion. Themes were developed and presented as findings and relevant quotes have been provided to support the findings. The study found factors such as self-stigma, knowledge about disability condition, financial challenges, location and accessibility challenges, communication challenges and lack of personal assistants which affect their access to healthcare. The experiences of disabled people have influenced them to construct their meanings regarding their conditions and subsequent health-seeking behavior. It is recommended that the district health directorate in collaboration with the National Commission for Civic Education should intensify public health education in the district which should be custom-made to suit the community's needs and understanding of disability taking into account local culture and belief system.
Background: Traditional bonesetters (TBS) are still highly patronized by people with fractures in Africa. We sought to investigate factors affecting the utilization of TBS services in the Northern Region of Ghana. Methods: A mixed-methods study that combined both qualitative and quantitative approaches was conducted among 64 TBS clients in the Northern Region of Ghana. Participants were purposively selected and should have utilized the services of TBSs at the time of the study. In addition, three focus group discussions (FGDs) were conducted to complement the quantitative results. Quantitative analysis was performed by calculating means and proportions. For the qualitative data, content analysis was done manually based on emerging themes in line with the study objectives. Results: Sixty-four (64) clients were recruited. Twenty-four (37.5%) were female. The modal age group was 19-39 years. The educational status of the clients was dominated by primary/junior secondary education (39.1%), but included the full spectrum from no formal education / illiterate (26.6%) to tertiary (12.5%). Cheaper fees (26.3%), cultural beliefs (17.9%), and quick service (15.9%) were the main reason of patronizing TBSs. Twenty-two (34.3%) would have preferred orthodox care and the reasons cited included availability of X-rays (27.3%) and pain management (25.3%). These themes were reiterated by FGDs with an additional 30 clients. Additional themes identified by the FGDs included a belief that TBSs address both physical and spiritual aspects of the injury and the major role that families (not the injured person alone) make in deciding on type of treatment. Clients were supportive of orthodox providers linking with TBSs for activities such as training to improve pain control. Conclusion: TBSs have patronage from the full spectrum of society. The decision to opt for TBS treatment was influenced by cheaper fees, cultural belief, and quick service. TBS clients wanted greater linkages between TBSs and orthodox providers.
Anemia among adolescent females is a major worldwide public health problem which should be given appropriate attention. Half of all anemic cases are caused by iron deficiency. In addition to anemia, poor nutrition is also a challenge in sub-Saharan Africa. This study determined the prevalence of anemia and undernutrition among adolescent females in school. A cross-sectional study was conducted among 151 adolescent females in four basic schools in the Ahafo region of Ghana. The hemoglobin level and anthropometry measures of participants were taken to determine their anemic and nutritional status. The prevalence of anemia among adolescent females in school was 50.3%. Out of the 151 participants, 6.6%, 19.9%, and 23.8% were severely anemic, moderately anemic, or mildly anemic, respectively. Only 2% of the participants were underweight, but the rate of stunting was 26.5%. The notable high prevalence of anemia that was found among adolescent females was correlated with other health and wellness concerns. Anemia and under nutrition negatively affect academic performance, productivity, and general wellbeing of adolescents; therefore, effective measures should be put in place to correct and eradicate these nutritional problems.
Barriers to treatment faced by people living with HIV (PLWH) have been well explored in the literature. Despite the importance of antiretroviral therapy (ART) in the treatment of HIV and prevention of AIDS, in the Ghanaian context only about 32% of infected persons have access to treatment. This underscores a need to understand the experiences of PLWH receiving ART to provide baseline information for policymakers' efforts to increase access to treatment. This study captures the voices of PLWH who were receiving ART in Ghana. A total of 35 participants receiving treatment in a hospital setting (11 males, 24 females; mean age 38 years, age range 21-60 years) took part in semi-structured face-to-face interviews to discuss their opinions about the cause of their HIV infection and its impact on their lives. The study found that the participants were susceptible to discrimination in their communities and at health care facilities. Some participants experienced marriage breakdowns, unemployment, social isolation, and were unable to perform everyday chores and responsibilities. Concerted efforts to address the barriers to treatment faced by PLWH are needed.
BACKGROUND:Iron Deficiency Anaemia (IDA) is reportedly high in pregnant adults and the causes well studied. However, among pregnant teenagers, the levels and associated factors of IDA are not fully understood. METHODS:In a prospective cohort study among Ghanaian pregnant teenagers, aged 13-19 years, IDA prevalence and associated factors were investigated. Sociodemographic data, household hunger scale (HHS), lived poverty index (LPI), FAO's women's dietary diversity score (WDDS) and interventions received during antenatal care (ANC) were obtained from 416 pregnant teenagers in Ashanti Region, Ghana. Micronutrient intakes using a repeated 24-hour dietary recall, and mid-upper arm circumference (MUAC) were determined and blood samples analysed for haemoglobin (Hb), serum levels of ferritin, prealbumin, vitamin A, total antioxidant capacity (TAC), C-reactive protein (CRP), and zinc protoporphyrin (ZPP). RESULTS:Anaemia (Hb cutoff <11.0 g/dL) was 57.1%; deficient systemic supply of iron stores (31.4%), depleted body stores of iron (4.4%), inadequate dietary iron intake (94.5%), and inadequate multiple micronutrient intakes (49.5%), were all notable among study participants. Between-subject effects using Generalized Linear Modelling indicated malaria tablet given at ANC (p = 0.035), MUAC (p = 0.043), ZPP (p<0.001), ZPP/Hb ratio (p<0.001) and depleted body iron stores (DBIS) (p<0.001) to significantly affect Hb levels. Pregnant teenagers with a high ZPP/Hb ratio (OR = 9.7, p<0.001, 95%CI = 6.0-15.8) had increased odds of being anaemic compared to those with normal ZPP/Hb ratio. Participants who were wasted (OR = 1.2, p = 0.543, 95%CI = 0.6-2.3), and those with depleted iron stores (OR = 3.0, p = 0.167, 95%CI = 0.6-14.6) had increased odds of being anaemic. Participants who experienced hunger were close to 3 times more likely (OR = 2.9, p = 0.040, 95%CI = 1.1-7.8) for depleted iron stores, compared to those who did not experience hunger. Also, participants with inadequate multiple micronutrients intakes (OR = 2.6, p = 0.102, 95%CI = 0.8-8.4), and those with low serum levels of ferritin (OR = 3.3, p = 0.291, 95%CI = 0.4-29.2) had increased odds of depleted body iron stores. CONCLUSIONS:IDA is common among pregnant teenagers and the related factors include malaria tablets given at ANC, maternal hunger, maternal MUAC, a deficient systemic supply of iron, depleted body iron stores, ZPP, and ZPP/Hb ratio. Appropriate interventions are urgently needed to address the causes of IDA among pregnant teenagers.
Inadequate nutrition during pregnancy can lead to adverse birth outcomes, and more importantly for pregnant adolescents as they require nutrients to meet their needs for their growth and the fetus. The study examined the relationship between nutritional status and birth outcomes among Ghanaian pregnant adolescents in selected districts of the Ashanti Region, Ghana. In this prospective cohort study, we followed 416 pregnant teenagers recruited at health centers during antenatal care until delivery. We measured weight and height to calculate Body Mass Index (BMI), and Mid-Upper Arm Circumference (MUAC), and nutrient intakes using a repeated 24 hr dietary recall were collected. Hemoglobin (Hb), serum levels of ferritin, prealbumin, vitamin A, Total Antioxidant Capacity (TAC), C-reactive protein (CRP), and Zinc Protoporphyrin (ZPP) were analyzed. Birth outcome data of interest were low birth weight (LBW) and preterm births (PTB). About 15.2 % had LBW, 12.5 % had PTB, and 3.1 % neonatal deaths. The majority of the pregnant adolescents consumed below Estimated Average Requirements (EAR) for thiamin (75.7 %), riboflavin (84.6 %), folate (82.9 %), vitamin A (87.3 %), iron (93.5 %), zinc (83.7 %), and calcium (96.9 %) intakes, while energy (96.6 %), protein (84.6 %), and dietary fiber (74.4 %) were below the Recommended Dietary Allowance (RDA). Anemia and wasting prevalences were 57.1 % and 27.8 %. The mean intakes for carbohydrates (p = 0.042) and dietary fiber (p = 0.012) were significantly higher among adolescent mothers with term birth (276.7 ± 111.2 g, 23.7 ± 11.2 g) than those with PTB (237.3 ± 83.7 g, 19.4 ± 9.0 g), respectively. Preterm birth proportions were higher in severely wasted (18.8 %) adolescents than moderately wasted (6.2 %) and normal MUAC (14.0 %) adolescents (p = 0.184). LBW proportions were higher among anemic (18.1 %) than the non-anemic (12.1 %), among low (30 %) compared with normal (14.9 %) serum ferritin, among low (15.7 %) compared with normal (0 %) serum prealbumin, and among low (16.2 %) compared with normal (11.1 %) serum vitamin A status pregnant adolescents. Pregnant adolescents with moderate wasting had lower odds (Adjusted odds ratio = 0.2, p = 0.017, 95 % confidence interval = 0.1–0.8) of having LBW infants compared with those with normal MUAC. The odds of preterm births were significantly higher among pregnant adolescents with dietary fiber intake below the RDA (Unadjusted OR = 2.8, p = 0.042, 95 % CI = 1.0–7.3). In conclusion, adverse birth outcomes were associated with poor nutritional status among pregnant adolescents studied.
Healthcare provider attitudes and perceptions of disability may influence the delivery of comprehensive quality care to patients with disabilities. The study was conducted to ascertain healthcare providers' perspectives on access to healthcare by disabled people in a peri-urban district of Ghana. We employed a qualitative approach and selected participants using the purposive sampling technique. Qualitative data were collected from 28 healthcare providers through face-to-face interviews using an interview guide. Data let thematic an alysis was employed to tease out the findings through categorisation and the main themes have been presented as findings with specific quotations to support them. We found that people with disabilities who visited healthcare facilities were perceived as individuals who are stressed up, selfish and inconsiderate, violent, having low self-esteem and also difficult to communicate with. This could affect the interactions between healthcare providers and people with disabilities who visit the facility and subsequently the quality of service provided. It is recommended that the Ministry of Education, Ministry of Health and the Ghana Health Service work closely with the various educational institutions to train healthcare professionals to improve their knowledge on disability issues to improve service delivery.
Context: Noncommunicable diseases (NCDs) such as cardiovascular diseases, cancers, hypertension, kidney diseases, and diabetes account for sizeable proportion of global deaths. The proximate causes aside biological and genetics are behavioral risk factors include dietary practices. Unhealthy dietary practice leading to the occurrence of NCDs blamed for the drawback of social and economic development of lower- and middle-income countries. Aims: This research focuses on establishing links among the political economy framework (education, occupation, income, residential place, and mass media), dietary practices, and the occurrence of NCDs in Ghana. Settings and Design: It adopted a mixed method approach using the Ghana Demographic and Health Survey (2014), with a sample of 4122 and 32 qualitative interviews from four regions. Subjects and Methods: In-depth, key informant interviews, focus groups discussions, and secondary data were used. The qualitative arm was analyzed using the thematic content analysis. Statistical Analysis Used: Descriptive statistics and probit regression were used to ascertain the influences of the constituents of political economy using individual's dietary intakes. Results: The present study found that, differences in income levels (P < 0.05), residential place of stay (P < 0.05), and access to mass media (P < 0.05) were statistically significant to dietary practices and had major implications for NCDs occurrence. The qualitative outcome revealed that, educational and occupational status of individuals may influence dietary practices. The regression revealed that females are exposed to unhealthy dietary practices by 6.2% points. Moreover, rural dwelling had moderate influence on unhealthy dietary practices (3.3% points) than urban dwelling. Again, professionals, sales, and service categories have 5.8%, 5.7%, and 7.6% points unhealthy practices, respectively.
Background and Purpose— White matter hyperintensities (WMHs) found on brain MRI in elderly individuals are largely thought to be due to microvascular disease, and its progression has been associated with cognitive decline. The present study sought to determine patterns of cognitive decline associated with anterior and posterior WMH progression. Methods— Subjects included 110 normal controls, aged ≥60 years, who were participants in the Duke Neurocognitive Outcomes of Depression in the Elderly study. All subjects had comprehensive cognitive evaluations and MRI scans at baseline and after 2 years. Cognitive composites were created in 5 domains: complex processing speed, working memory, general memory, visual-constructional skills, and language. Change in cognition was calculated using standard regression-based models accounting for variables known to impact serial testing. A semiautomated segmentation method was used to measure WMH extent in anterior and posterior brain regions. Hierarchical multiple linear regression models were used to evaluate which of the 5 measured cognitive domains was most strongly associated with regional (anterior and posterior) and total WMH progression after adjusting for demographics (age, sex, and education). Results— Decline in complex processing speed was independently associated with both anterior ( r 2 =0.06, P =0.02) and total WMH progression ( r 2 =0.05, P =0.04). In contrast, decline in visual-constructional skills was uniquely associated with posterior progression ( r 2 =0.05, P <0.05). Conclusions— Distinct cognitive profiles are associated with anterior and posterior WMH progression among normal elders. These differing profiles need to be considered when evaluating the cognitive correlates of WMHs.