Abstract— Blood and serum concentrations of selenium have been determined in a group of psychiatric patients and in 35 healthy controls. The psychiatric group consisted of 14 schizophrenics, seven paranoid disorders, six affective psychosis (manic‐depressive), four reactive psychosis, 11 dementia senilis, 17 with a diagnosis of neurosis and two with delirium tremens. Normal values were found in all groups except for delirium tremens where decreased blood and serum values were found.

FEBS LettersVolume 128, Issue 1 p. 137-141 Full-length articleFree Access Insulin-dependent protein phosphorylation in membranes Isolation and characterization of a phosphorylated proteolipid from sarcolemma O. Walaas, O. Walaas Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorK. Sletten, K. Sletten Biochemical Institute, University of Oslo, Oslo, NorwaySearch for more papers by this authorR.S. Horn, R.S. Horn Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorE. Lystad, E. Lystad Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorA. Adler, A. Adler Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorAa.R. Alertsen, Aa.R. Alertsen Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this author O. Walaas, O. Walaas Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorK. Sletten, K. Sletten Biochemical Institute, University of Oslo, Oslo, NorwaySearch for more papers by this authorR.S. Horn, R.S. Horn Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorE. Lystad, E. Lystad Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorA. Adler, A. Adler Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorAa.R. Alertsen, Aa.R. Alertsen Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this author First published: June 01, 1981 https://doi.org/10.1016/0014-5793(81)81099-XCitations: 7AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 J.R. Seals, J.M. McDonald, L. Jarett, J. Biol. Chem., 254, (1979), 6991– 6997. 2 G.J. Belsham, R.D. Denton, J.A. Tanner, Biochem. J., 192, (1980), 457– 467. 3 P.L. Tran, B. Desbuquois, FEBS Lett., 116, (1980), 149– 152. 4 R.J. Marchmont, M.D. Houslay, FEBS Lett., 118, (1980), 18– 24. 5 O. Walaas, E. Walaas, E. Lystad, Aa. Rye Alertsen, R.S. Horn, S. Fossum, FEBS Lett., 80, (1977), 417– 421. 6 O. Walaas, E. Walaas, E. Lystad, Aa. Rye Alertsen, R.S. Horn, Mol. Cell. Endocrinol., 16, (1979), 45– 55. 7 L.C. Mokrasch, Prep. Biochem., 2, (1972), 1– 19. 8 E. Gaetjens, Biochemistry, 15, (1976), 40– 45. 9 K.W. Cleland, E.C. Slater, Biochem. J., 53, (1953), 547– 556. 10 G. Fairbanks, T.L. Steck, D.F.H. Wallach, Biochemistry, 10, (1971), 2602– 2617. 11 R.T. Swank, K.D. Munkres, Anal. Biochem., 39, (1971), 462– 477. 12 V.P. Skipski, R.F. Peterson, M. Barclay, Biochem. J., 90, (1964), 374– 378. 13 G.A. Blondin, Biochem. Biophys. Res. Commun., 87, (1980), 1087– 1094. 14 D.H. MacLennan, Can. J. Biochem., 53, (1975), 251– 261. 15 A.S. Reeves, J.H. Collins, A. Schwartz, Biochem. Biophys. Res. Commun., 95, (1980), 1591– 1598. 16 F.J. Dowd, B.J.R. Pitts, A. Schwartz, Arch. Biochem. Biophys., 175, (1976), 321– 331. 17 B. Forbush III, J.H. Kaplan, J.F. Hoffman, Biochemistry, 17, (1978), 3667– 3676. 18 T.B. Rogers, Lazdunski, FEBS Lett., 98, (1979), 373– 376. 19 M. Bárány, K. Bárány, E. Gaetjens, A. Steinschneider, Biochim. Biophys. Acta, 491, (1977), 387– 397. 20 N. Nelson, E. Eytan, B. Notsani, H. Sigrist, K. Sigrist-Nelson, C. Gitler, Proc. Natl. Acad. Sci. USA, (1977), 74– 21 D.E. Green, M. Try, G.A. Blondin, Proc. Natl. Acad. Sc. USA, 77, (1980), 257– 361. 22 S.L. Alper, K.G. Beam, P. Greengard, J. Biol. Chem., 255, (1979), 4864– 4871. Citing Literature Volume128, Issue1June 01, 1981Pages 137-141 ReferencesRelatedInformation

In a previous report we have shown that insulin increases the phosphorylation of an endogenous protein of mol. wt. 16 000 daltons in sarcolemma membranes. In the present work we have demonstrated that phosphorylations of exogenous histones by the sarcolemma membranes are also increased by insulin. These results indicate that insulin activates a cyclic-AMP-independent protein kinase in sarcolemma membranes. The stimulatory effect of insulin on protein phosphorylations is increased by GTP and its analogue GMP-P(NH)P. The insulin effect was increased 3–4-fold by micromolar concentrations of GTP. The effect by the analogue GMP-P(NH)P was somewhat less. In the absence of insulin guanosine nucleotides had no effect on phosphorylation of the proteins. The results suggest that GTP is a modulator in the activation of a sarcolemma membrane protein kinase by insulin.

FEBS LettersVolume 80, Issue 2 p. 417-422 Full-length articleFree Access A stimulatory effect of insulin on phosphorylation of a peptide in sarcolemma-enriched membrane preparation from rat skeletal muscle O. Walaas, O. Walaas Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorE. Walaas, E. Walaas Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorE. Lystad, E. Lystad Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorAa.R. Alertsen, Aa.R. Alertsen Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorR.S. Horn, R.S. Horn Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorS. Fossum, S. Fossum Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this author O. Walaas, O. Walaas Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorE. Walaas, E. Walaas Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorE. Lystad, E. Lystad Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorAa.R. Alertsen, Aa.R. Alertsen Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorR.S. Horn, R.S. Horn Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this authorS. Fossum, S. Fossum Institute of Medical Biochemistry, University of Oslo, Oslo, NorwaySearch for more papers by this author First published: August 15, 1977 https://doi.org/10.1016/0014-5793(77)80489-4Citations: 34AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume80, Issue2August 15, 1977Pages 417-422 ReferencesRelatedInformation

Acta Psychiatrica ScandinavicaVolume 39, Issue S180 p. 423-424 ABNORMAL EFFECTS OF PREALBUMIN FROM SERA OF PSYCHOTIC PATIENTS ON METABOLISM OF RAT DIAPHRAGM Eva Walaas, Eva Walaas FROM THE INSTITUTE FOR MEDICAL BIOCHEMISTRY, UNIVERSITY OF OSLO, NORWAY, AND LIER MENTAL HOSPITAL, DRAMMEN, NORWAYSearch for more papers by this authorOttar Lingjserde, Ottar Lingjserde FROM THE INSTITUTE FOR MEDICAL BIOCHEMISTRY, UNIVERSITY OF OSLO, NORWAY, AND LIER MENTAL HOSPITAL, DRAMMEN, NORWAYSearch for more papers by this authorOddmund Sövik, Oddmund Sövik FROM THE INSTITUTE FOR MEDICAL BIOCHEMISTRY, UNIVERSITY OF OSLO, NORWAY, AND LIER MENTAL HOSPITAL, DRAMMEN, NORWAYSearch for more papers by this authorAase Rye Alertsen, Aase Rye Alertsen FROM THE INSTITUTE FOR MEDICAL BIOCHEMISTRY, UNIVERSITY OF OSLO, NORWAY, AND LIER MENTAL HOSPITAL, DRAMMEN, NORWAYSearch for more papers by this authorOtto Walaas, Otto Walaas FROM THE INSTITUTE FOR MEDICAL BIOCHEMISTRY, UNIVERSITY OF OSLO, NORWAY, AND LIER MENTAL HOSPITAL, DRAMMEN, NORWAYSearch for more papers by this author Eva Walaas, Eva Walaas FROM THE INSTITUTE FOR MEDICAL BIOCHEMISTRY, UNIVERSITY OF OSLO, NORWAY, AND LIER MENTAL HOSPITAL, DRAMMEN, NORWAYSearch for more papers by this authorOttar Lingjserde, Ottar Lingjserde FROM THE INSTITUTE FOR MEDICAL BIOCHEMISTRY, UNIVERSITY OF OSLO, NORWAY, AND LIER MENTAL HOSPITAL, DRAMMEN, NORWAYSearch for more papers by this authorOddmund Sövik, Oddmund Sövik FROM THE INSTITUTE FOR MEDICAL BIOCHEMISTRY, UNIVERSITY OF OSLO, NORWAY, AND LIER MENTAL HOSPITAL, DRAMMEN, NORWAYSearch for more papers by this authorAase Rye Alertsen, Aase Rye Alertsen FROM THE INSTITUTE FOR MEDICAL BIOCHEMISTRY, UNIVERSITY OF OSLO, NORWAY, AND LIER MENTAL HOSPITAL, DRAMMEN, NORWAYSearch for more papers by this authorOtto Walaas, Otto Walaas FROM THE INSTITUTE FOR MEDICAL BIOCHEMISTRY, UNIVERSITY OF OSLO, NORWAY, AND LIER MENTAL HOSPITAL, DRAMMEN, NORWAYSearch for more papers by this author First published: November 1964 https://doi.org/10.1111/j.1600-0447.1964.tb04956.xCitations: 3AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume39, IssueS180November 1964Pages 423-424 RelatedInformation

The basal content of pyridine nucleotides, and the synthesis of the coenzymes induced by parenteral injection of nicotinamide, have been investigated in the rat liver, when exposed to the action of insulin, adrenaline and ACTH. The basal content has been investigated after injection of insulin, or adrenaline, and in alloxan diabetic rats. The significance of the rather small variations in the basal content is discussed. In the induced synthesis of DPN the injection of insulin, or ACTH, has been found to interfere with this process, giving a decrease in the elevated content of DPN. The hormone action has been related to the mechanism of increased turnover of the DPN molecule. The administration of ethionine likewise decreased the elevated level of DPN. The significance of a regulatory influence of hormones on the induced synthesis of DPN has been discussed.