One of the most common causes of intestinal dysbiosis (DC) is the use of antibiotics, which, because of their antibacterial spectrum of action, can suppress the vital activity of intestinal microorganisms and significantly change the "microbial landscape" of the gastrointestinal tract. The article describes a new form of medications called ecoantibiotics, which along with the antibacterial component contain prebiotic lactulose, which reduces the damaging effects of antibiotics on intestinal biocenosis. The use of these drugs can maintain the balance of intestinal microflora and support intestinal microecology of the patient during treatment, significantly reduces the risk of candidiasis and intestinal lesions associated with C. difficile (antibiotic-associated diarrhea).