A clinical example shows the erroneous diagnosis of listeriosis in a 15-year-old child hospitalized in the infectious department. The child was admitted with severe symptoms of intoxication, febrile fever, difficulty in nasal breathing, hyperemia of the mucous membranes of the oropharynx, tonsillitis, cervical lymphadenitis, facial tissue pasteness with swelling of the eyelid and conjunctivitis of the left eye, hepatosplenomegaly. A laboratory examination revealed pronounced leukocytosis up to 24 thousand, lymphocytosis, atypical mononuclear cells up to 9%, IgM and IgG to EBV capsid protein, IgM to CMV, IgM and IgG to listeria. But with a repeated double study of IgM and IgG to Listeria were not detected. The initial positive result was possibly due to the presence of cross-reacting antibodies in EBV mononucleosis. The final diagnosis was made: Infectious mononucleosis of mixed (EBV, CMV) etiology. Chronic polypous rhinosinusitis, exacerbation. Reactive edema of the eyelids against the background of inflammation of the sinuses.Given the variety of clinical forms of listeriosis and their similarity with the manifestations of other infections, for the full diagnosis of listeriosis infection, it is advisable to evaluate the epidemiological and medical history data, as well as use an extended spectrum of laboratory confirmation of the diagnosis.

The article presents an extensive clinical experience about the treatment and prevention of influenza by oseltamivir for children and adults including high-risk group patients through different countries around the world over the past 17 years. The article reveals the causes of resistance to oseltamivir with a relative evolution proportion. The new domestic drug Nomides (oseltamivir), which manufactured by Pharmasintez JSC (Russia) in accordance with the Good Manufacturing Practice (GMP), has been represented in the article by unique dosage forms 30 and 45 mg on the Russian market for childrens older than one years old.

The data on the frequency of the spread of antibiotic-associated diarrhea (AAD) in children. A different incidence of AAD in children of different age groups, highest in children under the age of 3 years. The possibility of reducing the frequency of its development when administered prophylactically domestic probiotic containing Lactobacillus — Acipol on the background of antibiotic therapy. Prophylactic Acipol can reduce the incidence of AAD in these patients is 21%, and reduce the duration and severity of diarrheal syndrome.

The data on the frequency of the spread of antibiotic-associated diarrhea (AAD) in children. A different incidence of AAD in children of different age groups, highest in children under the age of 3 years.The possibility of reducing the frequency of its development when administered prophylactically domestic probiotic containing Lactobacillus — Acipol on the background of antibiotic therapy. Prophylactic Acipol can reduce the incidence of AAD in these patients is 21%, and reduce the duration and severity of diarrheal syndrome.

The data on the causal effects of interferons (IFN) and interferon inductors on a wide range of respiratory viruses and stimulate the immune system. The mechanism of action of interferon inductors, provides an assessment of the efficacy and safety of domestic drug Amixin® (tiloron) for the treatment and prevention of acute respiratory viral infections and influenza in adults and children over 7 years. Application of Amixin® reduced the duration of the main symptoms of the disease contributed to the normalization of the immune status, reduced the incidence of SARS and influenza complications. Appointment of Amixin® in children older than 7 years with chronic herpes virus infection, has contributed to the clinical and laboratory remission and improvement of lymphocyte subpopulation composition.