Comorbidity of chronic obstructive pulmonary disease (COPD) and metabolic syndrome (MS) creates the need of comprehensive approach to treatment, and prevention and rehabilitation of the patients. The aim . The objective of this study was to evaluate clinical efficacy of a comprehensive pulmonary rehabilitation program in patients with COPD and MS. This program was based on patient education, smoking cessation, physicaltraining, and nutritional correction in addition to the standard treatment of COPD. Methods. The study involved 70 patients (27 women (38.6%) and 43 men (61.4%) with stable moderate COPD and MS aged 18 to 60 years (mean age, 48.31±0.64 years). The patients were randomly divided into two groups: 35 patients were involved in a pulmonary rehabilitation program in addition to the standard therapy of COPD; other 35 patients were treated with the standard therapy. Clinical and laboratory parameters were assessed at baseline and in 12 months. Results . To the end of the study the groups differed significant in number of COPD exacerbations, emergency calls, hospitalizations, clinical symptoms of COPD and impact of the disease on physical activity and health status of the patients, quality of life (QOL), and physical tolerance. Conclusions: Management of patients with comorbid COPD and MS should include specific educational programs and physical training in order to improve treatment efficacy and quality of life of the patients.

Aim. The aim of this study was to evaluate clinical efficacy of a rehabilitation program for patients with bronchial asthma (BA) and comorbid metabolic syndrome (MS). Methods . This randomized study involved 60 stable patients (15 males) with moderate BA and comorbid MS. The mean age of the participants was 49.81 ± 0.77 years. BA was diagnosed according to GINA, 2011. The patients randomly received standard medication therapy plus education and physical training or standard therapy only. Clinical symptoms of BA, lung function, quality of life and nutritional status were assessed at baseline and in 12 months. Results. In 12 months, patients treated with rehabilitation program in addition to the standard therapy have demonstrated significant improvement in all parameters in comparison to patients treated with standard therapy only. Conclusion . Implementation of this program focused on education and physical training was related to a significant reduction in BA exacerbation rate, number of emergency calls and hospitalizations due to BA, decrease in severity of daytime and nighttime asthma symptoms, improvement in lung function, and achievement the optimal BA control.

The aim of this study was to assess effects of non-thermal microwave electromagnetic radiation (NMER) on asthma control and quality of life of patients with bronchial asthma (BA). Methods. Sixty outpatients with moderate BA aged 18 to 60 years were treated with NMER using the "Aster" device, 4 courses for 10 days of each Results. Clinical and spirometry parameters, asthma control and quality of life were significantly improved in comparison with BA patients receiving the standard therapy only. Conclusion. Thus, NMER in BA outpatients allowed increasing efficacy of therapy and prevention.

An acute exacerbation of chronic obstructive pulmonary disease (COPD) plays an important role in the disease progression and significantly reduces the patients' quality of life. The aim of this review was to summarize published findings about a possible role of biomarkers in diagnosis, management and predicting outcomes in COPD patients. Creactive protein and serum amyloid A are the most investigated biomarkers in this field. Measurement of copeptin and proadrenomedullin may be useful in predicting shortterm outcomes. Biomarkeroriented management of patients with acute exacerbation of COPD could be important for choosing medications.