Up to now the results of drug treatment are unsatisfying. Treatment of more than 1-2 years did not decrease the occurrence of relapses. Thyroid suppression test and TRH test give the same indications concerning the outcome in cases with Graves' disease and disseminated autonomy (short-time prognosis). The relapse rate is distinctly higher in Graves' disease than in cases with disseminated autonomy (goitre class 3 excluded).

In a prospective study we dealt with the following questions: Are antibody titers indicative of the course of disease? Which relations exist between thyroid suppressibility, antibody titer levels and relapse rates? Is high-dose methimazole treatment more effective than low-dose therapy?

On the basis of own experiments in the operative treatment of the vesico-uretero-renal reflux and of urinary stasis kidneys in childhood it is referred to the significance of the isotopic nephrography for the control of the course. The ING does not replace the IVU, but on account of its slight radiation stress and the unproblematic application of the radiopharmacon it is to be preferred to the secretion urogramme after the operation of disturbances of the micturition, when many problems arise.