In an open study 28 patients were treated for complicated UTI with ciprofloxacin 250 mg every 12 h for 10 days. The most frequently isolated species were Escherichia coli and Klebsiella pneumoniae. All pathogens were sensitive to ciprofloxacin in vitro. Twenty-three of the 28 patients (82%) were free of infection 5-9 days after therapy. A persistent infection was noted in two patients (7%) and a reinfection in three patients (11%). Four to six weeks after the end of therapy, 18 patients (64%) were still totally free of infection. Clinical resolution of symptoms and signs occurred in 27 patients (96%). Adverse reactions were spontaneously reported by four of the 28 patients (14%) and by 11 (39%) after detailed inquiry. Most side effects were of gastrointestinal or neurological nature. This small open study supports the view, that ciprofloxacin may be useful in the treatment of complicated UTI.

Abstract The expectation values of operators in state space between symmetrized or antisymmetrized coherent states associated with the Weyl group are introduced as classical functions. The dequantization scheme provided by these functions yields an interpretation of permutational symmetry for classical trajectories. The two-nucleon system is treated as an example.

Operators in Bargmann-Hilbert space are dequantized by associating with them a classical function on phase space. Three types of classical functions are considered. They are defined as expectation values between coherent states, symmetrized coherent states and antisymmetrized coherent states. Classical equations of motion are derived through the time-dependent variational principle. For symmetric and antisymmetric dequantization the solutions are given by pairs of trajectories. The method is applied to the relative motion of two nucleons with an effective Gaussian interaction. In a one-dimensional model, the lines of constant energy on phase space show the strong non-local contributions to the interaction. According to the time-dependent variation principle, the trajectories of the solutions must coincide with these lines. The Pauli principle has the following effect: antisymmetric dequantization yields a significant repulsion whereas symmetric dequantization yields additional attraction, compared with the dequantization through coherent states.