Brian Pham | AMiner学者主页

订阅小程序

旧版功能

开通会员低至0.73元/天

一次搞定AI科研

立即登录

English

联系方式

全面呈现 [Brian Pham] 的学术影响力

深度挖掘高质量成果与权威引用，让优秀看得见

研究兴趣

暂无数据

论文（2）

专利

基金项目

按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选

1Acyl Dipeptides As Reversible Caspase Inhibitors. Part 2: Further Optimization

SD Linton,DS Karanewsky,RJ Ternansky,N Chen, M Guo,KG Jahangiri,VJ Kalish,SP Meduna,ED Robinson,BR Ullman,JC Wu,B Pham,

A new structural class of broad spectrum caspase inhibitors was optimized for its activity against caspases 1, 3, 6, 7, and 8. The most potent compound had low nanomolar broad spectrum activity, in particular, single digit nanomolar inhibitory activity against caspase 8.

2002BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2002）引用：31

引用

AI阅读

2Acyl Dipeptides As Reversible Caspase Inhibitors. Part 1: Initial Lead Optimization.

SD Linton,DS Karanewsky,RJ Ternansky,JC Wu,B Pham,L Kodandapani,R Smidt,JL Diaz,LC Fritz,KJ Tomaselli

Parallel synthesis was used to explore the SAR of a peptidomimetic caspase inhibitor. The most potent compound had nanomolar activity against caspases 1, 3, 6, 7, and 8.

2002Bioorganic & Medicinal Chemistry Letters（2002）引用：53

引用

AI阅读