Sera prepared with two different strains of Salmonella typhi were analysed against all the soluble antigens isolated from S. typhi 0901, S. typhi Ty2 and S. typhi Vi. Agar-gel diffusion against individual sera showed that, in all the sera, antibodies were induced against somatic antigens and free proteins. Absorptions of the sera with polysaccharides, split from the somatic antigens, removed the antibodies induced against the polysaccharide and its proteinic carrier in most of the somatic antigens of S. typhi 0901. The antibodies left in the absorbed sera reacted against the proteinic moieties of more complex somatic antigens of S. typhi and against free proteins from all the analysed strains. Only the absorption with proteins removed all the precipitating antibodies from the sera. Moreover, in incomplete absorptions with proteins, the first antibodies removed are the antipolysaccharides, since antibodies are never induced against the haptenic polysaccharide but against somatic conjugates; in these the proteinic moiety eventually varies with every batch of bacteria. The sera exhausted of precipitins still agglutinate the bacteria, thus confirming the assumption that agglutinins and precipitins may be different antibodies.
Research Articles| October 01 2008 Contributions à l'étude des Salmonelles: Protéines communes des Salmonelles appartenant aux groupes B, C, D et E, et leur relation avec Citrobacter ballerup Subject Area: Further Areas , Oncology , Pathology and Cell Biology Cella Barber; Cella Barber Travail du Département de Bactériologie de l'Université de Tel-Aviv Search for other works by this author on: This Site PubMed Google Scholar E. Eylan; E. Eylan Travail du Département de Bactériologie de l'Université de Tel-Aviv Search for other works by this author on: This Site PubMed Google Scholar Yaffa Keydar Yaffa Keydar Travail du Département de Bactériologie de l'Université de Tel-Aviv Search for other works by this author on: This Site PubMed Google Scholar Pathologia et Microbiologia (1968) 31 (3): 165–174. https://doi.org/10.1159/000162014 Article history Published Online: October 01 2008 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Cella Barber, E. Eylan, Yaffa Keydar; Contributions à l'étude des Salmonelles: Protéines communes des Salmonelles appartenant aux groupes B, C, D et E, et leur relation avec Citrobacter ballerup. Pathologia et Microbiologia 1 March 1968; 31 (3): 165–174. https://doi.org/10.1159/000162014 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsPathobiology Search Advanced Search Article PDF first page preview Close Modal 1968Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Applying a method of selective separation of the specific high polymers the intracellular site of the specific substance in the Copenhagen strain of Pneumococcus Type II was demonstrated, by electron microscopy; the specific polymeric material assumed to form the capsule is situated within the bacterial cell and the electron density of this material is sufficiently high to permit its detection.The possibility of obtaining electron micrographs of the polymeric substances as contained in the cells or after their diffusion into the medium or when secreted as slime, suggests that the current concept of the capsules as the site of the specific substances may have to be reviewed.The electron micrographs were made by Dr A. Petrovici to whom I express my thanks.