Le dosage d'IgEs garde une place preponderante au niveau du diagnostic de l'allergie et en particulier dans certaines pathologies telles celles induites par des allergenes dangereux comme le latex par exemple. L'apport des allergenes recombinants constitue un element significatif au niveau des dosages des IgEs,c'est ce que nous avons observe pour le latex. La sensibilite du k82 recombi est significativement superieure a celle du k82. Elle permettra un meilleur depistage des patients sensibilises au latex et donc une meilleure prevention par l'absence de contact frequent avec les gants de latex, les detergents.
Measurement of IgEs keeps a predominant place in the diagnosis of allergy and in particular in certain pathologies such as those induced by dangerous allergens like, for example, latex. The contribution of recombinant allergens is a significant element in the measurement of IgEs and we have observed this for latex. Sensitivity of recombinant k82 is significantly greater than that of k82. It permits better detection of patients who are sensitised to latex and thus a better prevention by absence of frequent contact with latex gloves and detergents.
The results of assay of IgE can only be expressed by a very imprecise system of classes. Quantification of the measurement of IgE by the method of the CAP-system of prognosis of allergic patients. Expression of IgE by a measurement of intensity of fluorescence allows the establishment of a decent curve for each allergen. It makes a method of predictive evaluation of risk of the allergy pathology for each allergen. It significantly improves the sensitivity, since it allows detection of IgE at levels less than 0.35 KUA/l. Thus it gives a considerable improvement for the clinician at the level of diagnosis avoiding the "gold standard" provocation test in allergy diagnosis as well at the level of prognosis.