The postnatal period involves significant emotional and relational shifts that can challenge early mother-infant interactions, particularly under conditions of psychosocial vulnerability (e.g., maternal anxiety/depression) or infant-related risk (e.g., preterm birth). Maternal mentalization, operationalized as Parental Reflective Functioning (PRF), is a key protective factor for sensitive caregiving and dyadic regulation. OBJECTIVES:This protocol describes a multicenter, open-label, single-arm feasibility study evaluating a brief, fully online, mentalization-based video-feedback intervention (VFI-RF). The study is designed to assess the feasibility and acceptability of the intervention, rather than its efficacy. We aim to recruit 48 mothers, 24 in each of two risk groups, through socio-health services and neonatal intensive care units. Risk Group 1 will include mothers with clinically significant depressive and/or anxiety symptoms, defined as EPDS > 9 and/or GAD-7 ≥ 10, whereas Risk Group 2 will include mothers of preterm infants, defined as infants born before 37 weeks of gestation. METHODS:The intervention consists of 8 + 2 synchronous online sessions over approximately 5 months. Mothers record brief everyday caregiving interactions (~5 min) to review with a trained clinician, focusing on the infant's internal states and reflective meaning-making. Assessments occur at baseline (T0, infant age ~3 months), post-intervention (T1, ~8 months), and follow-up (T2, ~12 months). Primary feasibility outcomes include recruitment/referral metrics, uptake, retention, assessment completion, missing data, and participant-reported acceptability. Secondary exploratory clinical outcomes include maternal PRF, symptoms, parenting stress, social support, and mother-infant attachment, evaluated via validated self-report questionnaires. RESULTS:The study is designed to evaluate referral and recruitment patterns, intervention uptake, and participant retention, as well as the acceptability and suitability of study procedures and outcome measures for a future controlled trial. Preliminary trajectories of change in maternal reflective functioning and early relational indicators will be examined descriptively and exploratorily. CONCLUSIONS:Findings will inform the feasibility and refinement of a brief online mentalization-based video-feedback intervention to support at-risk mother-infant dyads during the first postnatal year. TRIAL REGISTRATION:Registered on Open Science Framework, osf.io/6g9ja, date of registration 4th March 2026.

Objective: this study, grounded in attachment theory and situated within the debate between categorical and dimensional approaches to attachment, aims to pursue two complementary objectives: firstly, to examine the differences in physical and mental health across different attachment styles; secondly, to analyze the specific contribution of internal working models (IWMs) in explaining these variations, allowing for an integrated interpretation of the results. Method: a total of 548 Italian adults participated in the study by completing selfreport questionnaires assessing the aforementioned study variables. For the first aim, univariate analyses of variance (ANOVAs) were conducted to test differences in physical and mental health according to different attachment styles; for the second aim, multiple linear regression analyses were performed by including physical and mental health as dependent variables and IWMs of the self and IWMs of others as potential explanatory variables. Results: the findings suggest that individuals with secure and dismissing attachment styles, both characterized by positive IWMs of the self, report better mental health when compared to those with preoccupied and fearful patterns, who are characterized by negative IWMs of the self. As for the second aim, IWMs of the self emerged as a substantially stronger predictor of mental health than IWMs of others. No associations were found with physical health. Conclusions: overall, the findings highlight the central role of attachment in adult mental health from an integrative perspective. While the categorical approach reveals clear differences in mental health across attachment styles, the dimensional analyses indicate that IWMs of the self constitute the primary mechanism underlying these differences. These results support the value of combining categorical and dimensional approaches to achieve a more comprehensive understanding of the relationship between attachment and health.

Background/Objectives: Cystic fibrosis (CF) is a genetic condition with an increasing life expectancy in recent years. As a result, addressing psychosocial aspects in this population has become an increasingly important concern. This mixed-methods systematic review aimed to update the current knowledge on the psychosocial aspects of living with CF in adults. Methods: Following PRISMA guidelines, a literature search was conducted in November 2024 across several databases, including Scopus, ScienceDirect, Academic Search Complete, MEDLINE, Supplemental Index, Complementary Index, APA PsycInfo, Business Source Complete, SciELO, and the Directory of Open Access Journals via EBSCO. Results: Of the 701 articles retrieved, 24 were analyzed, including a total of 2023 participants (mean age: 31.2 years; 57.2% female). Quantitative findings identified optimistic coping as the most frequent strategy associated with improved survival. High social support and gratitude emerged as key factors for treatment adherence and quality of life, while depression remained the primary mental health concern. Qualitatively, the findings highlighted concerns with adult life transitions and financial stressors. Participants described experiences of social stigma and embarrassment linked to chronic symptoms, often leading to selective disclosure to avoid discrimination. Conclusions: This review confirms that psychosocial factors are central to the adult CF experience, shifting the focus beyond biological survival and highlighting areas that require clinical intervention. As life expectancy increases, clinical care must evolve to incorporate interventions that address these factors to improve mental health and overall quality of life (QoL), ensuring that patients are supported through the unique challenges of extended adulthood.

Despite the widespread prevalence of cancer diagnoses among parents of underage children, there is a limited body of research in this specific area, and even fewer tools have been developed to assess the impact of cancer on parenting roles. The present cross-sectional study aimed to analyze the psychometric properties of the Italian version of the Parenting Concerns Questionnaire (PCQ), including its convergent validity with parents’ and children’s psychological distress. A total of 411 adults with cancer and minor children (i.e., < 18 years old; mean age = 12.15 years; SD = 5.11) completed the PCQ and measures of anxiety, depression, children’s emotional and behavioral problems, and quality of parent–child relationship. Statistical analyses indicated good psychometric properties of the PCQ and demonstrated small to moderate correlations with the psychological distress experienced by both parents (anxiety and depression) and children (emotional and behavioral problems). The PCQ proves to be a valuable screening tool that can be easily used by healthcare professionals to identify specific parenting concerns and challenges faced by parents with cancer.

Fear of missing out (FoMO) creates a strong urge to stay continuously connected and informed about peers’ activities, identified as a risk factor for problematic social media use and risky behaviors. Sexting is generally defined as the exchange of sexually suggestive or explicit photos, videos, or text messages through cell phones or other technologies. Despite its social relevance, the link between FoMO and sexting remains underexplored. This study examines their relationship in young adults—an understudied group compared to adolescents—while controlling for age, sex, and sexual orientation. The study surveyed 911 Italian young adults (18–30 years, Mage = 22.3, SDage = 2.57, 74% women, 70.4% heterosexual) through an online questionnaire. The results indicate that FoMO predicts only risky sexting behaviors (sexting under substance use and sexting for emotion regulation) while not influencing experimental sexting (sending one’s own sexts). Additionally, the link between FoMO and sexting for emotion regulation is stronger among LGB individuals. Therefore, FoMO has proven to be strongly related to the two kinds of risky sexting but not to experimental sexting. Understanding this relationship can inform prevention and intervention programs on relationships, online communication, and sexting in young adults.

While there is much research on the individual correlates of sexting, the relationship with personal values is understudied. This study aimed to investigate whether adolescents and young adults (14–21 years old) involved in different sexting behaviors (i.e., experimental sexting, non-consensual sexting, sexting under pressure, risky sexting) have distinct value orientations according to Schwartz’s model. A self-report questionnaire was completed by 719 Italian participants (52.6% females; M age = 16.82; SD age = 1.59). A series of multivariate analysis of variance (MANOVA) analyses showed that all forms of sexting were related to higher openness to change values (hedonism and stimulation) and self-enhancement values (power and achievement) and to lower conservation values (conformity) and self-transcendence values (universalism). Sexting under pressure was also related to higher importance placed on tradition values. Significant moderation effects of age and sex also emerged. Prevention programs for sexting should promote values that counteract power dynamics in relationships and overcome gender stereotypes.

Background: Pediatric rheumatic diseases (PRDs) are a group of chronic disorders that start in childhood and are characterized by periodic exacerbations and remissions of symptoms, with limitations in family, school, and social activities. The aim of this study was to detect differences in parents’ psychological adjustment and emotion regulation strategies, and parent-reported children’s adjustments in families of children with active and inactive PRDs. Methods: Fifty-four parents (38 mothers and 16 fathers) of children with PRD were recruited from a pediatric unit. Disease activity was evaluated by their pediatric rheumatologist, while parents’ depressive and anxiety symptoms, emotion regulation strategies, and children’s emotional difficulties and hyperactivity–inattention symptoms were assessed through a web-based survey. Results: Parents of children with active PRDs reported higher levels of their child’s emotional difficulties and hyperactivity–inattention symptoms. Linear regression analysis demonstrated that having a child in the active phases of PRD and lower use of cognitive reappraisal lead to higher children’s emotional symptoms, while active disease, low use of cognitive reappraisal, and greater expressive suppression were associated with higher hyperactivity–inattention symptoms. Our study highlights that children with PRDs and their parents may be at increased risk for psychological problems, especially during the active disease phase, highlighting the importance of a multidisciplinary approach.

A mother's cancer diagnosis may have consequences for all family members, particularly for children, since it makes a parent less physically and emotionally available, with effects on the relationship with the child and his/her development. The main aim of this study was to analyze children's psychological adjustment in the context of maternal cancer by considering factors related to the child (i.e., age and sex), the mother (psychological adjustment), and cancer (i.e., time elapsed from the diagnosis and current oncological treatment). Self-report questionnaires investigating mothers' parenting stress, depression, anxiety, and children's emotional and behavioral problems were administered to 124 mothers (mean age = 44.52 years; SD = 7.22) diagnosed with cancer. A hierarchical regression analysis highlighted that time since diagnosis and mothers' anxiety and parenting stress accounted for almost 44% of the variance of the children's difficulties. Maternal depression, current oncological treatment, and the child's age and sex were not statistically significant. Higher mothers' parenting stress and anxiety and a longer time elapsed since the first diagnosis predicted higher levels of children's emotional and behavioral problems. These findings highlight the need to identify precursors of childhood distress in the context of maternal cancer and to develop structured programs to support both mothers and children.

The COVID-19 pandemic could be a threat for the health status of children with a chronic condition. The present study aimed to explore parents’ and children’s psychological adjustment during the current pandemic, pursuing a triple objective: to compare the psychological adjustment of parents of children with pediatric rheumatic diseases (PRDs) and parents of healthy children; to analyze children’s psychological symptoms (emotional problems and hyperactivity) before and during the COVID-19 pandemic, and with or without a PRDs diagnosis; to explore the associations of children’s emotional problems and hyperactivity with parents’ psychological adjustment, parent–child interactions and belonging or not to families with PRDs. This cross-sectional study involved 56 parents of children with PRDs and 53 parents of healthy children. Self-report questionnaires about parents’ depression, anxiety, parenting stress, and children’s emotional symptoms and hyperactivity-inattention were administered. No differences were detected on psychological adjustment between parents of children with PRDs and parents of healthy children. Parents of children with PRDs reported statistically significant higher levels of children’s emotional problems and hyperactivity before the pandemic, compared to parents of healthy children; during COVID-19 pandemic, emotional symptoms increased for both groups, while hyperactivity-inattention symptoms increased only in the group of healthy children. Children’s emotional difficulties were associated with higher levels of parental anxiety, worse parent–child interaction and having PRDs; children’s hyperactivity symptoms were related to parent–child difficult interaction and higher levels of parental depression. Findings suggest the importance to target the children in relation to their parents, when approaching the psychological aspects of PRDs.

The present study aimed to analyze the differences between maternal and paternal parenting stress and children’s behavioral functioning, as determined by teacher and parent reports. In addition, it sought to evaluate the presence of clusters based on parenting stress and to determine whether perceptions of children’s behavioral functioning varied across these clusters. The sample was composed of the parents and teachers of N = 201 children. Parents completed a self-report questionnaire on parenting stress and parents and teachers filled out report-form questionnaires assessing children’s emotional and behavioral functioning. The results showed that mothers had higher levels of parenting stress than fathers, and both parents reported more prosocial behavior in children than did teachers. Furthermore, middle stressed parents had children who expressed more prosocial behavior than did parents in other clusters. The findings also showed that parenting stress influenced partners’ perceptions of children’s behavioral functioning. The multiplicity of child observers facilitated a better understanding of how parenting stress, linked to parent–child interactions, may play an important role in shaping parents’ perceptions of their children.

The COVID-19 outbreak resulted in a large amount of emotionally charged messaging that is believed to have a tremendous psychological impact, particularly on children and early adolescents. The present study examined the relationships between children's exposure to COVID-19 news, children's emotional responses to the news, parental styles of mediating COVID-19 news, and children's emotional functioning during the COVID-19 lockdown in Italy in April 2020. An online survey was completed by 277 parents (Mage = 43.36; SDage = 4.76; mothers = 89.5%) with children aged 6 to 13 years. Regression analyses showed that the parental active mediation style was associated with higher emotion regulation and lower lability/negativity, whereas the restrictive style was associated with higher lability/negativity and the social coviewing style was associated with lower emotion regulation. The results provide evidence for how adults using an active style can mediate messages to reduce children's emotional difficulties during events with high emotional involvement.

The current cross-sectional study aimed to analyse adolescents' adjustment during and before the lockdown caused by the coronavirus disease 2019 pandemic, by evaluating levels of emotional problems and hyperactivity as referred by adolescents themselves. A further purpose was to compare adolescents' and mothers' perception about adolescents' adjustment. Participants comprised 206 adolescents (50.5% females; mean age = 12.2; SD = 3.3) and their mothers (mean age = 43.9; SD = 5.9). Findings showed that levels of emotional symptoms and hyperactivity in adolescents during the pandemic were significantly higher than before. This worsening was consistently detected by both mothers and adolescents themselves. Two main conclusions are highlighted by the current research: During the first wave of the COVID-19 pandemic, adolescents participating to this study detected a worsening in their well-being; mothers' perceptions of their adolescents' psychological problems may be considered reliable and consistent with the offspring's point of view. PRACTITIONER POINTS: Italian adolescents' adjustment during the COVID-19 outbreak has been little investigated. The current study highlighted a worsening in adolescents' well-being, in terms of higher emotional symptoms and hyperactivity, with respect to the pre-pandemic period. This worsening was consistently highlighted by both adolescents themselves and their mothers.

Purpose To investigate the way carriers of a BRCA1/2 pathogenetic variant make their reproductive decisions and to examine the factors associated with the choice of preimplantation genetic diagnosis (PGD) and prenatal diagnosis (PND). Methods We conducted a comprehensive literature search in PubMed, Scopus, and Web of Science in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method. Results A total of 16 articles published from 2000 to 2021 were included in this review. Data were overall collected from 3564 participants (86% females). Three important themes were identified across studies: changes in family planning, factors associated with family plans, and with acceptance or regret of PGD and PND. Conclusion This review may contribute to the knowledge of the experience of those who have a BRCA1/2 mutation and want a child. These results may help genetic counselors and healthcare professionals that support people with a BRCA pathogenetic variant with reproductive issues.

Several authors found that somatic symptoms during pregnancy such as nausea, vomiting, and levels of sleep, and fear of childbirth were associated with women’s post-partum psychopathological difficulties. The present study aimed to verify whether fear of childbirth can mediate the relationship between some somatic symptoms experienced during pregnancy (i.e., nausea, vomiting, and daily sleep duration) and the post-partum depressive and anxious symptoms. N = 258 mothers of children between 3 and 6 months of age filled out self-report questionnaires assessing somatic symptoms during pregnancy, fear of childbirth, and anxious and depressive symptoms during post-partum. Results showed that levels of vomiting during pregnancy (but not nausea and daily sleep duration) was associated with post-partum depression and anxiety. Furthermore, findings showed that fear of childbirth partially mediated the relationships between the levels of vomiting during pregnancy and post-partum state anxiety and depression. These results can have several clinical implications, allowing to implement preventive programs for post-partum depression, considering vomiting and fear of childbirth as important risk factors.

The present study, carried out during the first peak of the COVID-19 outbreak in Italy, aimed at investigating the mental health of mothers and children during the nationwide lockdown. More specifically, the study investigated children's depression and mothers' individual distress and parenting stress, in comparison with normative samples. The mediating effect of mothers' parenting stress on the relationship between mothers' individual distress and children's depression was also explored. Finally, the study analyzed whether children's biological sex and age moderated the structural paths of the proposed model. A sample of 206 Italian mothers and their children completed an online survey. Mothers were administered self-report questionnaires investigating individual distress and parenting stress; children completed a standardized measure of depression. Mothers' individual distress and parenting stress and children's depression were higher than those recorded for the normative samples. Mothers' parenting stress was found to mediate the association between mothers' individual distress and children's depression. With respect to children, neither biological sex nor age emerged as significant moderators of this association, highlighting that the proposed model was robust and invariant. During the current and future pandemics, public health services should support parents-and particularly mothers-in reducing individual distress and parenting stress, as these are associated with children's depression.

International research has underlined the role played by children’s and maternal psychopathological symptoms on the onset of avoidant/restrictive food intake disorder (ARFID) in early childhood. No study has considered the possible interplay between children’s dopamine transporter (DAT1) genotype and methylation, dysregulation problems and maternal psychopathological risk. This study aimed to investigate the complex relationship between these variables, considering the possible mediation role played by children’s DAT1 methylation on the relationship between mothers’ psychopathological risk and children’s dysregulation problems, moderated by children’s DAT1 genotype. Our sample consisted of 94 early children and their mothers, divided into four subgroups, based on children’s ARFID subtypes (irritable/impulsive (I/I), sensory food aversions (SFA), post-traumatic feeding disorders subtypes (PTFD), and a non-clinical group (NC)). We addressed children’s dysregulation problems and maternal psychopathological risk, and collected children’s DNA through buccal swabs. Results showed that children’s 9/x genotype was associated with PTFD and NC groups, whereas the 10/10 genotype was associated with the SFA group, with large effect size. There were significant large differences in the study groups on children’s DAT1 total methylation, children’s dysregulation problems, and maternal psychopathological risk. Children’s DAT1 methylation did not mediate the relationship between mother’s psychopathological risk and children’s dysregulation problems, but there was a significant large direct effect. Children’s 9/x genotype moderated the relationship between maternal psychopathological risk and children’s DAT1 methylation but, respectively, with a large and small effect. Our pilot study suggested that the relationship between children’s DAT1 genotype and methylation, dysregulation problems, and maternal psychopathological risk has a crucial contribution to ARFID.

Abstract Background The purpose of this study was to explore fathers' adjustment and father–child relationships during the first peak of the coronavirus disease 2019 (COVID‐19) outbreak (April 2020). More particularly, the study analysed paternal perceptions of changes concerning familial economic conditions and children's psychological difficulties (viz., emotional problems and hyperactivity) during the lockdown produced by the current pandemic. Furthermore, we investigated the following correlates of fathers' parenting stress: socio‐demographic condition, paternal individual stress, anxiety, depression and changes in the father–child relationship during the outbreak. Methods A total of 102 fathers (mean age = 41.60 years; SD = 11.54) with minor children were recruited through an online survey and reported data about their socio‐economic condition, anxiety, and depressive levels, parenting stress, offspring's adjustment, and changes in their relationship with their children. Results As for the economic conditions, participants were equally distributed between those who did not perceive changes and those who perceived a worsening. With regard to changes in the child's psychological difficulties, results showed that levels of children's emotional problems and inattention/hyperactivity had significantly increased during the lockdown period. A multiple linear regression analysis highlighted that the principal predictor of paternal parenting stress was living in the regions most affected by the COVID‐19 pandemic, followed by high levels of paternal anxiety symptomatology and high levels of worsening of the relationship with the child during the pandemic. Conclusions Overall, our study suggests to consider the effects of COVID‐19 on fathers as well, as they have been rather overlooked by previous research that has mainly focused on mothers, and to plan specific interventions able to also take them into account.

Adolescence is considered a critical period of life, with the body and the emotional experience occupying a central role in the individual's development. Previous research highlights the influence of biological, psychological and socio-cultural factors on the adolescent's body experience. In fact, interactions with parents may have an impact on the development of body image during childhood and adolescence, especially in females. The first aim of the study was to investigate the bodily experience of female adolescents in order to detect the variables that can play a role in its development, such as the relationship with parental figures and the ability to recognize and express emotions. In addition, we analysed differences in alexithymia and body experience between younger adolescents (i.e., < 17 years old) and older adolescents (i.e., >= 17 years old). The current research has shown, through a multiple linear regression analysis, that alexithymia (18.4% of explained variance) and maternal emotional availability (2.8% of explained variance) were significant predictors of bodily experience. Furthermore, younger adolescents had higher scores on both alexithymia and negative bodily experience than older adolescents, indicating the presence of greater difficulties both in physical experience and in the ability to recognize and express emotions.

BACKGROUND An inconclusive result from BRCA1/2 genetic testing indicates that a genetic variant of uncertain significance is detected. This case constitutes the majority of genetic test results, but studies specifically addressing the psychological adjustment of people with inconclusive results are scarce. AIM To examine psychological outcomes of receiving an uninformative BRCA1/2 test result. METHODS PubMed, PsychInfo, and Cochrane Central Register of Controlled Trials were screened for studies focusing on distress, anxiety, and depression levels in individuals with inconclusive genetic test results. This review is based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method. RESULTS Studies on psychological outcomes of inconclusive BRCA1/2 focused on general and specific distress, anxiety, and depression. Overall, they produced mixed results. These inconsistent findings are probably due to the uncertainty caused by this type of result, that may also influence the decisions of individuals about surveillance and prophylactic options, reducing their compliance. In addition, this review highlights specific risk and protective factors that affect psychological adjustment in individuals with an inconclusive genetic testing result. CONCLUSION Individuals with inconclusive genetic test results need specific educational programs and support to better understand the meaning of their results in order to be able to make decisions about surveillance and prophylactic options.