Early detection of colorectal cancer (CRC) improves survival. The impact of primary prevention for adenomas has been studied but so far no firm recommendations have been made.

Adenomatous polyps are predictors of cancer and advanced adenomas. Certain characteristics alert endoscopists about features suggestive of malignancy. Early Colorectal Cancer (CRC) limited to the superficial submucosa, is considered a low-risk disease for lymphatic and blood dissemination. In these cases, Endoscopic Mucosal Resection (EMR) can be considered a therapeutic option. 1) To describe a large series of colonic polyps resected by Endocoscopic Mucosal Resection (EMR), 2) To estimate the prevalence of High Grade Dysplasia (HGD) and early carcinoma in this cohort. reports from EMR of colonic polyps were reviewed Colonoscopies were performed at an outpatient' GI clinic, in Buenos Aires city, between 2004 and 2009. EMR consisted on a submucosal saline injection technique, and main outcome measurement was the description of resected lesions. VCCSTAT 2.0. 394 EMR of 25000 colonoscopies were performed in this period. 48% (190/394) were males. Average age was 56 years (min 24 - max 88 years).All patients were white. 1. With regards polyps 'description the most prevalent findings were : by morphology: non - polyploidy lesions were detected in 70% (95% CI 64 - 75); by location: most lesions were in right colon :43% (95% 39-49); by size: most prevalent size was >10 and ≤ 20 mm in 53% [95% CI 46- 57]; by histology: tubular adenoma was the most prevalent lesion, diagnosed in 33% (95% CI 28- 38). 2. The prevalence of HGD and early carcinoma was 19% (95% CI 15-23). Predominant characteristics of these 68 lesions are described in table 1.Table 1Predominant characteristics of lesions with HGD and early adenocarcinomaMost prevalent characteristics of lesionsN lesions%(95% CI)MorphologyPolypoid3857 (44 - 69)LocationRectum2232 (21 - 44)Size>10 and ≤ 20 mm2133 ( 22 - 46)HistologyHGD3957 (44 - 69) Open table in a new tab According to these results, morphology and location cannot be used to infer histology as benign and malignant lesions are different in these features. HGD and early carcinoma can be detected in fifth of these lesions, so efforts should aim to promote and improve this effective and safe technique.