CSF1 administration expands tissue macrophages, which transforms systemic metabolism. CSF1 drives fat mobilization and glucose uptake to support liver growth. The effects of CSF1 are independent of normal hormonal metabolic regulation. The effects of CSF1 are rapidly reversible, restoring homeostatic body composition. CSF1-dependent macrophages and liver size are coupled in a dynamic equilibrium.
Jesse J R Masson合作论文数1Fathima Nooru-Mohamed合作论文数1
Michelle Ferrari-Cestari合作论文数Mater Research Institute, The University of Queensland1Lena Batoon合作论文数1
Allison Pettit合作论文数Mater Research Institute, Faculty of Medicine, The University of Queensland1
Kamil Sokolowski合作论文数Department of Chemistry, University of Cambridge1
David Hume合作论文数Mater Research Institute, Translational Research Institute, Faculty of Medicine, University of Queensland1
Robert Parton合作论文数Centre for Cell Biology of Chronic Disease, Institute for Molecular Bioscience, University of Queensland;School of Biomedical Sciences, Faculty of Medicine, University of Queensland1
Patkar Omkar合作论文数1
Liviu Gabriel Bodea合作论文数1
Keshvari Sahar合作论文数Mater Medical Research Institute1Katharine M. Irvine合作论文数Institute for Molecular Bioscience, University of Queensland1
Mitchell A Sullivan合作论文数1Hilmar Ebersbach合作论文数1
Kim Summers合作论文数Royal School of Veterinary Studies, The University of Edinburgh1
