often conflicting as concerns organ radiosensitivity.However, Corring et at.(1975) studying swine, showed the effects on exocrine secretion of a single irradiation (at 600 and at 800 rd) of the hind-half of the body. Material and methodsA. -Animals.Eight adult Corsican pigs, weighing a mean 61 kg (47-82 kg) were used.Before the experiments, they were fitted with two indwelling catheters (Silastic ND), one of 2 X 4 mm in the jugular vein and one of 3 X 5 mm in the stomach.B. -Irradiation conditions (fig.1).The conscious pigs, suspended in a sling, were irradiated using eight sources of about 1 000 curies of IO C O , placed four by four on each side of the animal ; two lead plates 75 X 45 cm and 7.5 cm thick, one on either side of the sling, protected the fore-part of the animal 2-3 cm in front of the xiphoid process.The irradiation dose was 1 100 rads at the body midline, and dose rate at the skin was about 45 R/min (or about 30 rd/min at the body midline).Under these conditions, about 10 p. 100 of the live bone marrow was conserved, which is sufficient for protection from the hematological syndrome.C. -Functional exploration of gastric and pancreatic secretions.Gastric and pancreatic samples were taken from the controls before irradiation (D 0) and then at D 3-4, D 10-12, D 16-18, D 21-22, D 26-28, D 30-32, D 38-46 after irradiation.1) Gastric exploration.a) Gastric samples were obtained by pumping the indwelling catheter, according to the technique of Zeitoun (1965) and Devaux (1970), using animals maintained on a hydric diet for 24 hrs before.The gastric liquid was collected in ice-cooled flasks for six consecutive 30-min periods, i. e. during a total of 3 hrs.* Swine body surface (m 2 ) = 9.9 3 !/P2liveweight in grams.

Tests of surgical treatments (graft of small intestine, and partial enter ectomy before or after irradiation) and dietetic treatments (continuous parenteral feeding) were carried out on 80 pigs irradiated over the posterior half of the body with doses of between 950 and 1750 rad at mid plane.

Nutritional balance of pigs irradiated on the hind part with 1 100 rd of 6 °Co gamma rays.The hind part of 10 adult miniature pigs was irradiated with 1 100 rd of s °Co gamma rays.The dietary mineral (Na, K, Ca, P), nitrogen and lipid balances of the animals were studied before and 1, 3 and 5 months after irradiation.While the classical early lesion of the intestinal mucosa recovered quite satisfactorily within one or two months, a pancreatic atrophy process developed progressively which might play a major role in the nutritional state of the pigs and thus in their survival.Concerning nutritional balance, nitrogen and sodium retention were perturbed until 5 months post-irradiation ; cyanocobalamin absorption remained very low.Dry and organic matter utilization recovered nearly normal values in the 3rd ou 5th month. Introduction.Les conséquences d'une irradiation abdominale aiguë au niveau du tube digestif ont donné lieu à de nombreuses études : la plus grande partie concerne les lésions histologiques et enzymologiques de la muqueuse intestinale.Les autres s'appliquent aux troubles fonctionnels qui englobent les phénomènes de sécrétion, d'absorption, de motricité, de circulation sanguine locale et d'écologie microbienne.Un certain nombre de revues bibliographiques et d'ouvrages ont développé ces différents points (Conard, 1956 ; Bond, 1963 ; Sullivan, 1968 ; Gorizontov, 1971 ; Daburon et al., 1975) après le travail de base de Quastler (1956).Mais les aspects nutritionnels du syndrome gastro-intestinal d'irradiation ont été peu abordés (Jehotte, 1954 ; White et al., 1955) à cause des difficultés à conduire une réanimation chez les petites espèces de laboratoire et de la courte survie des animaux.Nous avons vu auparavant l'intérêt du porc dans ce type d'études, applicables à l'homme (Daburon et Duée, 1976).Dans la mesure où la dose d'exposition n'est pas trop élevée et permet une cer- taine restauration de la muqueuse (jusqu'à 1 100-1 200 rd chez le porc, Daburon et