To study the correlation between fetal soft tissue measurements (midthigh subcutaneous tissue thickness (MTST), abdominal subcutaneous tissue (ASCT) and fetal thigh volume (TVol)) with neonatal body composition. In this prospective observational study, 111 women carrying single, structurally and chromosomally normal fetus with correct dates were enrolled. Women with chronic medical disorders, intrauterine death and newborn requiring NICU admission were excluded. Ultrasound was done at 28 and 36 weeks of gestation, fetal biometry, ASCT, MTST, and TVol was measured. Neonatal body composition was calculated using formula given by Catalano, from skin fold thickness at triceps, biceps, sub scapular and suprailiac area. The mean age of the mothers was 26.89 + 3.34 years. The fetal soft tissue measurements at 28-29 weeks of pregnancy was were ASCT (mm) 3.92 + 0.69 mm; MTST (mm) 3.29 + 0.69 mm; T vol (cm3) 23.34 + 5.74. At 36-37 weeks ASCT was 4.93 + 0.89; MTST was 4.6 + 0.30 and Tvol was 50.30 + 12.84. Neonatal body composition showed fat mass as 0.312 + 0.15 kg; fat free mass was 2.56 + 0.24 kg and % body fat 10.67 + 4.95. At 28 weeks ASCT correlated with neonatal fat mass (p = .05) and neonatal fat free mass (p = 0.018). Thigh volume correlated with neonatal fat free mass (p = .006). At 36 weeks ASCT significantly correlated with neonatal fat mass (p = .008) and neonatal fat free mass (p = .001). MTST did not correlate with any component of neonatal body composition. Thigh volume correlated significantly with neonatal fat mass (p = .001), neonatal fat free mass (p = .001) and neonatal body fat (p = .01) Near term fetal thigh volume best correlates with neonatal fat mass, percentage body fat and fat free mass. This correlation with body fat was not seen at 28 weeks ofgestation, possibly fat deposition takes place in third trimester.

Background: Moderate (Haemoglobin (Hb) 7-9.9g/dl) and severe anaemia (Hb <7g/dl) during pregnancy increase the risk of postpartum haemorrhage (PPH). Objectives were to investigate the association between coagulation parameters and severity of anaemia during pregnancy and relate these to blood loss at childbirth. Methods: A prospective cohort study of 1342 pregnant women in the third trimester from 10 hospitals across India. Hb and coagulation parameters: fibrinogen, D-dimer, D-dimer/fibrinogen ratio, platelets, and INR were measured at baseline. Participants were followed-up to measure blood loss within two-hours after childbirth, and ‘high blood loss’ was measured for a threshold ≥500ml. Associations between coagulation parameters, anaemia and blood loss were examined. Findings: In women with severe anaemia during the third trimester, the D-dimer was 27% higher, mean fibrinogen 117mg/dl lower, D-dimer/fibrinogen ratio 69% higher, and INR 12% higher compared to women with no/mild anaemia. Mean platelets in severe anaemia was 37.8X109/L lower compared with women with moderate anaemia. Similar relationships with smaller effect sizes were identified for women with moderate anaemia compared with women with no/mild anaemia. Lower Hb at baseline significantly increased the odds of high blood loss at childbirth, and a stronger effect was moderated by an increase in D-dimer. Interpretation: Altered blood coagulation profile in pregnant women with severe anaemia may be a risk factor for PPH and requires further evaluation. Funding Statement: The study is funded by a Medical Research Council (GCRF) Career Development Award to Manisha Nair (Grant Ref: MR/P022030/1) and Nuffield Department of Population Health – Pumppriming award. Declaration of Interests: The authors declare that they have no competing interests. Ethics Approval Statement: The study was approved by the institutional review boards (IRB) of each coordinating Indian institution, namely: Srimanta Sankaradeva University of Health Sciences, Guwahati, Assam; Nazareth hospital, Shillong, Meghalaya; Emmanuel Hospital Association, New Delhi; Mahatma Gandhi Institute of Medical Sciences, Sevagram, Maharashtra; and the Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh. It also received approval from the Government of India’s Health Ministry’s Screening Committee, the Indian Council of Medical Research, New Delhi and by the Oxford Tropical Research Ethics Committee (OxTREC), University of Oxford, UK. Written informed participant consent was taken from all participants.

To review the indications and results of diagnostic prenatal invasive procedures performed in a tertiary care referral institution. This prospective study included 141 pregnant women, between 11-26 weeks of gestation, who underwent various invasive diagnostic procedures in the Division of Maternal Fetal Medicine, All India Institute of Medical Sciences, New Delhi during August 2018 to January 2019. A total of 145 procedures including 79 CVS, 52 amniocentesis and 14 cordocentesis were performed during this period. A history of genetic disorders in previous pregnancies /family history prompted a diagnostic evaluation in the current pregnancy in 48.94% (n = 69) of cases. Abnormal result on aneuploidy screening was another common indication for performing these procedures (n = 23, 16.31%). CVS was the most common procedure (n = 79, 54.48%) performed, with common indications being a previous baby affected with thalassemia major (19/79), Duchenne's muscular dystrophy (8/79) or spinal muscular atrophy (7/79). Amniocentesis was the second most common procedure performed (n = 52, 35.86%), with the most common indication being an abnormal result on aneuploidy screening (22/52). The results of the invasive tests were abnormal in 19 (13.48%) cases, while results could not be obtained in 8 (5.67%) cases. Of 141 patients, 33 (23.40%) patients opted for medical termination of pregnancy based on the results of the prenatal invasive testing or on account of presence of gross congenital malformations in the fetus. No procedure related pregnancy loss was noted on follow up to 2 weeks, after the procedure. Prenatal invasive procedures are a safe and feasible option for diagnosis of a wide range of chromosomal, single gene disorders or metabolic abnormalities in the index pregnancy. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Caesarean scar ectopic, where the gestational sac implants in the myometrium at site of previous Caesarean section (CS), is an unusual complication of CS. We describe subsequent successful pregnancy in two cases managed conservatively. Case 1: G4P1L1 was referred at 7 weeks pregnancy with a diagnosis of Caesarean scar ectopic. MRI confirmed the diagnosis (figure 1). She had a previous CS and a D&C. Her previous pregnancy was Caesarean scar ectopic for which laparotomy was done and area of scar ectopic excised. This pregnancy was managed with intrasac KCL injection as it contained a live fetus, and systemic methotrexate (total 3 doses) followed by bilateral uterine artery embolisation. HCG became negative at 12 weeks follow up and sac completely resolved by 6 months. She conceived 2 years later, had term Caesarean section, LSCS scar was intact. Case 2: Referred as incomplete abortion with vascular retained products of conception. Ultrasound showed a vascular heterogenous mass 4x5cm in area of lower uterine segment. A diagnosis of Caesarean scar ectopic was made. She had a previous Caesarean delivery. Bilateral uterine artery embolisation was done and patient followed with HCG values. The mass resolved in 5 months. Patient conceived after one year. She underwent a Caesarean hysterectomy for placenta increta. Conservative medical management is feasible in Caesarean scar ectopic pregnancy. Treatment can be tailored to individual patient. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

To perform a retrospective review of the trends in management of Rh isoimmunised pregnancies from the tertiary care referral in the country over the last 16 years. A retrospective record review was conducted for all the procedures performed in the last 16 years. The study period was divided into three time periods. The first from 2001-2010, the next from 2011 to 2014 and third from 2015 to 2016. Over the last 16 years we have given 1023 IUTs to 389 women and presently it is over 100 IUTs every year. There is better awareness among physicians and the cases referred with hydrops has reduced by 50% (43% to 21%). However still around 20% of patients present with hydrops because of poor antenatal and postnatal management of Rh-negative mothers. On an average an immunised fetus needed 2-3 IUTs, however even up to 7 IUTs were performed in some fetuses. The POG at first IUT is mostly around 26-28 wks however there was a trend towards earlier IUTs in the later time period. With better techniques of monitoring and managing Rh Isoimmunised pregnancies, the period of gestation at delivery was gradually delayed from 34-35 weeks to 36-37 weeks. Around 40% fetuses were delivered vaginally during all the time periods. The procedure related complications have come down from 8.57 % in the earlier phase to 4.9 % in the more recent times. The overall survival improved in the hydropic of fetuses improved from 70% to than 93% during this period while the survival of the non hydropic fetuses was consistently good at around 90%. The principles of successful management of Rh isoimmunised preincludes timely prophylaxis, intensive serial US and Doppler monitoring of isoimmunised cases and fetal blood transfusion in cases of severe anemia. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

ABSTRACTObjectiveTo compare virtual autopsy using postmortem magnetic resonance imaging (MRI) with conventional autopsy with respect to phenotypic characterization of stillbirths and malformed fetuses, and acceptability to parents.MethodsThis was a prospective diagnostic evaluation study, conducted from June 2013 to June 2015, including stillbirths and pregnancies terminated owing to fetal malformation at ≥ 20 weeks' gestation, for which parental consent to both conventional autopsy and postmortem MRI was obtained. Cases of maternal and obstetric cause of fetal demise were excluded. Whole‐body postmortem MRI (at 1.5 T) was performed prior to conventional autopsy. Taking conventional autopsy as the diagnostic gold standard, postmortem MRI findings alone, or in conjunction with other minimally invasive prenatal and postmortem investigations, were assessed and compared for diagnostic accuracy.ResultsParental consent for both conventional autopsy and postmortem MRI was obtained in 52 cases of which 43 were included in the analysis. In 35 (81.4%) cases, the final diagnosis based on virtual autopsy with postmortem MRI was in agreement with that of conventional autopsy. With conventional autopsy as the reference standard, sensitivity, specificity, positive and negative predictive values of postmortem MRI were, respectively: 77.7%, 99.8%, 97.4% and 98.0% for whole‐body assessment; 93.1%, 99.0%, 87.1% and 99.5% for the nervous system; 61.0%, 100.0%, 100.0% and 96.7% for the cardiovascular system; 91.1%, 100.0%, 100.0% and 98.0% for the pulmonary system; 80.6%, 99.8%, 96.7% and 98.7% for the abdomen; 96.2%, 99.7%, 96.2% and 99.7% for the renal system; and 66.7%, 100.0%, 100.0% and 97.2% for the musculoskeletal system. Virtual autopsy was acceptable to 96.8% of families as compared with conventional autopsy to 82.5%.ConclusionsVirtual autopsy using postmortem MRI and other minimally invasive investigations can be an acceptable alternative to conventional autopsy when the latter is refused by the parents. Postmortem MRI is more acceptable to parents and can provide additional diagnostic information on brain and spinal cord malformations. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.

To study the correlation between placental volume and vascularisation indices in first trimester with birthweight. This is an observational study, conducted from July 2015 to June 2017 at All India Institute of Medical Sciences, India. Low risk, pregnant women between 11 and 13 + 6 weeks gestation with live singleton pregnancy were recruited in this study. Women with difference of > 6 days in gestational age by LMP and CRL were excluded. At 11 and 13 + 6 weeks scan, CRL and nuchal translucency was measured (FMF guidelines). Placental volume and placental vascularisation indices were calculated using 3D power Doppler and the virtual organ computer-aided analysis (VOCAL) in Voluson E-8, ultrasound machine (GE Medical systems). Vascularisation indices determined were vascularisation index (VI), flow index (FI) and vascularisation flow index (VFI). Participants underwent routine antenatal care. Pregnancy outcomes noted were mode of delivery, period of gestation at birth, birthweight and any pregnancy related complications. For purpose of analysis placental volumes were expressed as MOM. 168 women completed the study. The mean age was 28.08± 3.2 yrs, mean BMI was 23.93 ± 12.51, mean gestation at recruitment was 12.5 ± .67 weeks, mean gestation at delivery was 38.7 ± 1.3 weeks and mean birthweight was 2917 ± 384 gms. Mean placental volume was 51.62 ± 17.24 cm3, mean VI – 41.27 ± 11.03, mean FI- 32.85 ± 5.58 and mean VFI was 13.80 ± 4.66. Placental volume correlated with CRL (r=0.486; p = 0.000). First trimester placental volume significantly correlated with birthweight, adjusted for gestational age (r = 0.266; p = 0.00). There was a correlation between VI (r=0.164, p = .034), FI (r =0.245, p = .001), VFI (r =0.24, p = .002) and birthweight. First trimester placental volume was not significantly smaller in SGA neonates (n=15) but was significantly more in 21 LGA neonates (p=0.017) compared to AGA neonates. First trimester placental volume and vascular indices correlated with birthweight. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

M. Sanz Cortes1, S. Monteiro1, R.G. Voigt1, A. Nassr4, M. Berretta1, P. Yun4, M.C. Braun3, C. Koh2, D. Roth2, R. Ruano5, M. Belfort4 1Meyer Centre for Developmental Pediatrics, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; 2Urology, Baylor College of Medicine & Texas Children’s Hospital, Houston, TX, USA; 3Renal Section, Baylor College of Medicine & Texas Children’s Hospital, Houston, TX, USA; 4Obstetrics and Gynecology, Baylor College of Medicine & Texas Children’s Hospital, Houston, TX, USA; 5Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA

To investigate the protective effects of aqueous seed extracts of fennel "Foeniculum vulgare" (FVE) and caraway "Carum carvi" (CCE) on liver, kidney and reproductive organs in female rats against cadmium chloride (CC) intoxication.A total of 36 adult female rats were divided into six groups, six in each group. Control group (fed normal diet), CC-treated group (50 mg CC/kg diet), CCE-treated group (150 mg CCE/kg diet), CCE + CC group, FVE (150 mg/kg diet) and FVE + CC. One month later, all rats were sacrificed and all samples were collected at proestrus phase.The toxic effects of CC were confirmed biochemically by significant increase of serum concentration of liver enzymes (P < 0.05), and creatinine (P < 0.001). Moreover, CC increased significantly the serum level of malondialdehyde (MDA) and decreased the total antioxidant capacity (TAC) (P < 0.001). In addition, serum concentrations of estrogen, progesterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) were significantly decreased (P < 0.01). Histopathologically, CC-treated group revealed marked pathological changes in renal, hepatic, ovarian and uterine tissues. All toxic findings observed in liver and kidney with CC treatment were found to be ameliorated markedly after co-treatments with FVE or CCE. Furthermore, co-treatment of FVE with CC improved significantly all studied reproductive parameters (P < 0.01).Both FVE and CCE could be used as efficient treatments for liver and kidney against CC intoxication. Moreover, FVE could be utilized as a potent treatment to protect and improve female fertility from cadmium intoxication.

Large placental chorioangiomas have been associated with a number of fetal complications including anemia, hyperdynamic circulation, hydrops and high perinatal deaths (18-40%). Fetal anemia may be caused by microangiopathic hemolysis in chorioangioma vessels, blood sequestration in the tumor or fetomaternal hemorrhage. We discuss a case of large placental chorioangioma, where prenatal diagnosis and management of fetal anemia with intrauterine transfusions resulted in successful pregnancy outcome. A primigravida was referred to us at 26 weeks pregnancy with a large placental chorioangioma, polyhydramnios and fetal anemia. Ultrasound at 18 weeks had shown a 4x3x3cm tumor. At the time of referral, the tumor was 10x8x8cm with high vascularity and raised middle cerebral artery- peak systolic velocity (MCA-PSV) suggesting severe fetal anemia. She received 3 intrauterine transfusions (IUT) to correct fetal anemia and one platelets transfusion, to correct thrombocytopenia. A Caesarean delivery was performed at 31 weeks for severe hyperdynamic circulation, reversed E/A ratio in right ventricle. A female child weighing 1.375 kg with Apgar score 7/9 at 1/5 min was delivered. Hematocrit at birth was 50%. Newborn developed jaundice at 2 hrs of age, requiring double volume exchange transfusion and phototherapy. Platelet transfusion was given twice to correct thrombocytopenia. Baby is doing well on follow up at 2 years of age. Supporting information can be found in the online version of this abstract Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

To determine the value of middle cerebral artery-peak systolic velocity (MCA-PSV) in detecting fetal anemia, for timing first and subsequent intrauterine transfusions. 186 Rh isoimmunised pregnant women were monitored for fetal anemia by MCA-PSV. First fetal blood sampling and intrauterine transfusion (IUT) was performed when MCA-PSV value was ≥ 1.5MOM or MCA-PSV <1.5 with cardiomegaly and ascites. Women with MCA-PSV ≥ 1.5 at 34 weeks or more were delivered and cord blood hematocrit (Hct) was correlated with MCA values. Subsequent transfusions were mainly based on rate of fall of Hct or if MCA-PSV was ≥ 1.5MOM. Of 186 women, 127 underwent first IUT. Mean gestational age (GA) and hemoglobin (Hb) at first transfusion were 26.7 ± 3.6 weeks and 6.1 ± 2.9 gm/dl. 89 women underwent second IUT, mean GA and Hb were 28 ± 3.4 weeks and 6.7 ± 2.1gm/dl. The mean GA and Hb of 61 women undergoing third transfusion was 29.6 ± 2.8 and 7.9 ± 2.3 respectively. At first IUT, 111/127 (87.4%) fetuses were anemic. MCA-PSV ≥ 1.5 had a sensitivity of 92% for detecting moderate to severe anemia with positive predictive value (PPV) of 88%, 8% cases were missed and 14 fetuses were wrongly diagnosed as having anemia. 59 non transfused fetuses were followed up till delivery by weekly Doppler, 5 had anemia at birth. Of 5 fetuses with MCA Doppler ≥ 1.5, only one was anemic. Of 89 fetuses undergoing 2nd IUT, 77(86.5%) were anemic. The sensitivity of MCA-PSV ≥ 1.5 for detecting moderate to severe anemia was 79% and PPV 91%; 16 cases were missed and 6 were wrongly diagnosed. At third IUT 45/61 (73.7%) fetuses were anemic, sensitivity was 57.7% and PPV 78.8%; 19 were missed, 7 were falsely diagnosed anemic. Doppler velocimetry is less accurate for the prediction of anemia in transfused fetuses compared to fetuses who have not undergone transfusion. Doppler velocimetry is not accurate for detecting fetal anemia after 34 weeks gestation.

Telomere length plays a significant role in various disorders; however, its role in idiopathic recurrent pregnancy loss (iRPL) is not known. The objective of this study was to assess telomere length in peripheral blood leukocytes in couples experiencing unexplained recurrent pregnancy loss (iRPL).

To diagnose cervical agenesis with functioning uterus in young girls with acute pain abdomen around the age of puberty by ultrasound, and to decide the feasibility and prognosis of utero-cervico-vaginal reconstructive surgery. Patients with acute dysmenorrhoea were evaluated clinically and by ultrasound. Ultrasound was done for presence of hematometra, size of uterus, hydrosalpinx and other associated anomalies. The possibility of reconstructing a functional utero-cervico-vaginal canal was made, and reproductive outcome noted. Fiftyeight (58) patients were diagnosed clinically and on ultrasound to have hematometra of various sizes and position. Complete vaginal and cervical atresia was seen in 54, partial in 2. Hematosalpinx was present in 46, endometrioma in 12, endometriosis in 9. There was fibroma in rudimentary horn in 1 case, single kidney in 9, pelvic kidney in 1, skeletal anomalies in 2, congenital heart defect in 3 girls. Ultrasound diagnosed large hematometra with single / unicornuate / bicornuate / didelphys average sized uterii in 42 cases - in whom laparotomy, abdomino-perineal cervico-vaginoplasty (CVP) in 41 cases, and laparoscopic CVP in 1 case, was performed successfully, with good reproductive outcome. Ultrasound showed large hematometra in 1 horn of uterus didelphys in 4 cases, vaginal cervicoplasty was done in 2 cases, hemi - hysterectomy in 2 cases. In 12 girls with severe dysmenorrhoea, ultrasound showed severe uterine hypoplasia with minimal hematometra. It was decided that CVP would not be useful in these cases with hypoplasia confirmed on laparoscopy / laparotomy, so hysterectomy was performed. Ultrasound was very useful in the workup of girls with severe dysmenorrhoea due to cervical agenesis with functioning uterus, for deciding successful utero-cervico-vaginal reconstruction or performing hysterectomy.

Prospective observational study carried out in a tertiary hospital in India. Group I: 200 high risk pregnancies. Group II: 100 high risk pregnancies with BPP ≤ 6/10. Fetuses with congenital anomalies, fetal infection, abnormal fetal karyotype were excluded. Fetal monitoring was done with weekly or more frequently if required Biophysical profile and Doppler velocimetry of the fetal umbilical artery. The result of the last Doppler and BPP examination within 7 days of delivery was correlated with perinatal outcome. Decision for expediting delivery was taken in case BPP ≤ 6/10, AEDF or REDF in umbilical artery, non-reassuring fetal heart rate or on the discretion of the attending physician. The sensitivity of Doppler and BPP was 96.15% and 92.31% respectively, the specificity was 68 %and 42 %, positive predictive value 89.9 and 81%, and negative predictive values were 86.6 and 66.6% respectively. The colour Doppler was abnormal before evidence of BPP abnormality by several days to weeks. Supporting information can be found in the online version of this abstract Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

International Journal of Gynecology & ObstetricsVolume 119, Issue S3 p. S322-S322 Free communication (oral) presentations O176 USEFULNESS OF SERIAL IVIG INFUSIONS WITH INTRAUTERINE TRANSFUSIONS IN SEVERE Rh-ALLOIMMUNISED PREGNANCIES A.K. Sharma, A.K. SharmaSearch for more papers by this authorD. Deka, D. DekaSearch for more papers by this authorV. Dadhwal, V. DadhwalSearch for more papers by this authorS. Bansal, S. BansalSearch for more papers by this authorA. Singh, A. SinghSearch for more papers by this author A.K. Sharma, A.K. SharmaSearch for more papers by this authorD. Deka, D. DekaSearch for more papers by this authorV. Dadhwal, V. DadhwalSearch for more papers by this authorS. Bansal, S. BansalSearch for more papers by this authorA. Singh, A. SinghSearch for more papers by this author First published: 22 October 2012 https://doi.org/10.1016/S0020-7292(12)60606-7AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume119, IssueS3Abstracts of XX FIGO World Congress of Gynecology and ObstetricsOctober 2012Pages S322-S322 RelatedInformation

International Journal of Gynecology & ObstetricsVolume 119, Issue S3 p. S322-S323 Free communication (oral) presentations O177 CERVICO-VAGINAL RECONSTRUCTIVE SURGERY FOR CERVICO-VAGINAL ANOMALIES D. Deka, D. DekaSearch for more papers by this authorV. Dadhwal, V. DadhwalSearch for more papers by this author D. Deka, D. DekaSearch for more papers by this authorV. Dadhwal, V. DadhwalSearch for more papers by this author First published: 22 October 2012 https://doi.org/10.1016/S0020-7292(12)60607-9AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume119, IssueS3Abstracts of XX FIGO World Congress of Gynecology and ObstetricsOctober 2012Pages S322-S323 RelatedInformation