This article make the summary of analysis of the external treatment of nephrotic syndrome in the current situation,which means including acupoints treatment,hyperbaric oxygen therapy,Washing method of Chinese medicine,Chinese medicine enema,etc; that the external treatment of nephrotic syndrome as one of the ways to support its worthy of further study of clinical applications.

The article is reviewed on the basis of biological function of CTGF,the relationship between CTGF and TGF-β1,the role of renal fibrosis and the research of Chinese medicine in renal fibrosis.It can provide targets and references of traditional Chinese medicine for the treatment of anti-renal fibrosis.