Pectointercostal Fascial Plane Block (PIFB) targets the anterior cutaneous branches of the intercostal nerves and provides analgesia to the anteromedial chest wall. In this study, we aimed to evaluate the effect of PIFB in addition to Serratus Anterior Plane Block (SAPB) on postoperative morphine consumption and pain scores in breast reduction surgery. Sixty-four ASA I–II patients (≥18 years) were randomly assigned to two groups. General anesthesia was induced with propofol, rocuronium, fentanyl, and maintained with sevoflurane and remifentanil. After intubation: Postoperative analgesia included IV morphine patient-controlled analgesia (1 mg bolus, 10-min lockout, 4-hour limit: 10 mg). Outcomes measured were stay in postanesthesia care unit time (PACU), 24-hour morphine consumption, morphine demands, VAS scores (rest and movement), additional analgesic use, and complications. Both groups had similar demographics, surgical duration, and PACU stay. 24-hour morphine consumption was lower in Group I (3.7±2.2 mg vs. 7.9±2.3 mg, p<0.05). Morphine demands were lower in Group I (4.5±2.7 vs. 10.4±3.7, p<0.05). VAS scores (rest and movement) were lower in Group I (p<0.05). Rescue analgesic requirement was lower in Group I than in Group I (p=0.01). No complications occurred in both groups. PIFB combined with SAPB significantly reduces morphine consumption and pain scores in breast reduction surgery without complications. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Introduction: Preoperative anemia is common in geriatric hip fracture patients and is associated with increased perioperative morbidity. This study aimed to evaluate the impact of preoperative anemia on postoperative outcomes in patients aged ≥65 years undergoing hip fracture surgery. Methods: A retrospective cohort study was conducted on 179 patients (≥65 years) who underwent surgery for traumatic hip fracture between 2019 and 2024 at Çukurova University Hospital. Patients were divided into anemic (hemoglobin <12 g/dL in women, <13 g/dL in men) and non-anemic groups. The primary endpoint was the incidence of postoperative adverse events, including cardiac, pulmonary, cerebral, and renal complications, and 30-day mortality. Secondary analysis compared outcomes based on transfusion thresholds (7–8 vs. 9–10 g/dL). Results: Of 179 patients, 77 (43%) had preoperative anemia. Anemic patients had significantly higher rates of intraoperative blood transfusion (40.2% vs. 18.6%, p=0.001), postoperative complications (41.6% vs. 28.4%, p=0.028), postoperative transfusion (53.2% vs. 27.4%, p<0.001), ICU admission (10.4% vs. 2.9%, p=0.002), and longer hospital stay (7.9 ± 4.9 vs. 6.7 ± 3.5 days, p=0.031). Thirty-day mortality was similar. Transfusion at Hb <8 g/dL showed a trend toward higher complications (62% vs. 45%, p=0.09). Conclusions: Preoperative anemia is an independent risk factor for perioperative morbidity in geriatric hip fracture patients. Routine preoperative anemia screening and optimization are recommended. Prospective trials are needed to define optimal transfusion thresholds.

Yüksek morbidite ve mortalite oranına sahip serebral anevrizmaların tek etkili tedavisi endovasküler veya cerrahi onarımdır. Bu girişimler, anevrizmaya sekonder subaraknoid kanamayı (SAK) tedavi etmede, daha fazla morbiditeyi engellemede ve aynı zamanda henüz rüptüre olmamış anevrizmalarda SAK’ı önlemede kullanılır. Serebral anevrizmaların, mikrocerrahi teknik ile anevrizmanın boynuna bir klip yerleştirilerek uygulanan cerrahi tedavisi etkili ve güvenli prosedürler olmakla birlikte belirli zorlukları da içerir. Özellikle de büyük yapılı, kritik serebral ve vasküler yapılara yakın ve derin yerleşimli anevrizmalarda klipaj aşaması oldukça kritiktir. Cerrahi anevrizma tedavisiyle ilişkili riskler arasında beyin retraksiyonu, geçici arteriyel tıkanıklık ve intraoperatif kanamanın neden olduğu yeni veya kötüleşen nörolojik defisitler yer alır. Bu riskleri azaltmak için, anevrizma boynunun klipajı aşamasında kan akımını geçici olarak durdurmada veya azaltmada kullanılan çeşitli yöntemler tanımlanmıştır. Bunlar arasında, hızlı ventriküler pacing (RVP), derin hipotermik kardiyak arrest (DHCA) ve adenozin kaynaklı hipotansiyon ve asistoli yer almaktadır. Anahtar sözcükler: Adenozin-ilişkili kardiyak arrest, intrakraniyal anevrizma cerrahisi, geçici kalp durması, kan akımı

Introduction: Various physiological and psychological effects of earthquakes can be seen on the human body, even without a direct physical impact from the earthquake. Both the experience of the earthquake process and the earthquake-related subsequent life changes cause stress through the activation of the sympathetic and parasympathetic systems in the body. This stress can affect various physiological processes, including the cardiovascular system. In this review, the effect of earthquakes on the cardiovascular system was aimed to be discussed in line with the available evidence. Discussion: There are studies showing that natural events such as earthquakes increase the incidence of adverse cardiac events, such as myocardial infarction, heart failure, hypertension, and sudden cardiac death, or cause existing cardiac diseases to worsen during these periods. However, there are also some evidences with conflicting results. Therefore, the effect of earthquakes on cardiovascular diseases has not been clearly demonstrated yet. Conclusion: Even survivors of earthquakes without physical injury are exposed to stress secondary to both internal and external factors. Studies indicate that individuals who are involved in the earthquake process may have adverse effects on cardiovascular health in the short and long term. Therefore, it is important to take necessary precautions and create appropriate conditions, especially in people with cardiovascular disease.

PURPOSE:Emergence delirium (ED) after sevoflurane anesthesia remains a serious issue in children. We aimed to compare different ratios of propofol-ketamine combinations to determine a better option for preventing ED. DESIGN:A prospective, randomized clinical trial. METHODS:In this study, 112 children aged between 3 and 12 years who underwent adenoidectomy and tonsillectomy were recruited. Propofol 1 mg kg-1 + ketamine 1 mg kg-1 (1:1 ratio), propofol 1.5 mg kg-1 + ketamine 0.75 mg kg-1 (2:1 ratio), propofol 2 mg kg-1 + ketamine 0.66 mg kg-1 (3:1 ratio), and propofol 3 mg kg-1 were applied at induction of anesthesia for Groups I, II, III, and IV, respectively. Fentanyl 1 mcg kg-1 and rocuronium 0.6 mg kg-1 were applied at induction, and anesthesia was maintained with sevoflurane and O2/N2O mixture for all participants. Intravenous morphine 0.1 mg kg-1 was applied for postoperative analgesia in the last 10 minutes of surgery. ED was defined as a Watcha score of ≥3. Demographics, hemodynamics, extubation time, Watcha scores, the Face, Legs, Activity, Cry, and Consolability scores, length of stay in the postanesthesia care unit (PACU), rescue analgesic requirement, and postoperative complications were recorded. FINDINGS:ED was significantly higher at 10 and 20 minutes in Group IV. Eighteen children experienced ED in PACU, (3, 2, 2, and 11 children in Groups I, II, III, and IV, respectively). Face, Legs, Activity, Cry, and Consolability scores were significantly different at all times. Rescue analgesics were required by 3 children (10.7%) in Group I, 2 (7.1%) in Group II, 2 (7.1%) in Group III, and 10 (35.7%) in Group IV (P = .012). The PACU stay was 21.9 ± 6.4 in Group I, 18.7 ± 6.3 in Group II, 16.7 ± 5.8 in Group III, and 17.4 ± 5.8 in Group IV. Nystagmus was observed in three children in Group I. CONCLUSIONS:To addition of ketamine to propofol during the induction of sevoflurane anesthesia can reduce the ED and analgesic requirements in children. A propofol-to-ketamine ratio of 3:1 provided better postoperative recovery with less pain and ED, without prolonging the PACU length of stay.

Giriş: Serebral perfüzyon basıncını azaltmak ve kanama riskini en aza indirmek için uyanma sırasında stabil hemodinamiği korumak oldukça önemlidir. Urapidil ve remifentanilin ekstübasyon kalitesi ve ekstübasyon sırasında hemodinami üzerindeki etkilerini karşılaştırmayı amaçladık. Materyal ve Metod: 18-65 yaş aralığında, ASA 1-3 dahil 90 hasta çalışmaya dahil edildi. Anestezi tüm gruplarda remifentanil 0,125-0,25 µg/kg/dk ve sevofluran %1-2 ile sürdürüldü. Grup I' de remifentanil infüzyonu ameliyatın son 15 dakikasında 0,02-0,03 µg/kg/dk' ya düşürüldü. Grup II' de remifentanil infüzyonu ameliyatın bitiminden 15 dakika önce durduruldu. 5 dakika sonra, urapidil bolus dozu (12,5 mg) verildi ve urapidil infüzyonu (3,2-4,8 μg/kg/dak) başlatıldı. Grup III'te, remifentanil infüzyonu ameliyatın bitiminden 15 dakika önce durduruldu ve urapidil infüzyonu (3,2-4,8 μg/kg/dak) başlatıldı. Hemodinamik veriler, entropi değerleri ve Glasgow Koma Skalası, son 15. dakikada ve ekstübasyondan sonraki 5. dakikaya kadar kaydedildi. Bulgular: Ekstübasyondan önce ve sonra SAP (sistolik arter basıncı), MAP (ortalama arter basıncı) ve DAP (diyastolik arter basıncı) ortalama değerleri arasında istatistiksel olarak anlamlı farklar gözlendi (p

Background: Controlled hypotension can reduce bleeding and improve visualization of the surgical field. We aimed to evaluate the effects of deliberate controlled hypotension by using esmolol and nicardipine on cerebral oxygenation, hemodynamics, bleeding, surgical satisfaction and quality of recovery. Methods: Sixty patients between the ages of 18 and 65 who were scheduled tympanomastoidectomy surgery were included. Anesthesia induction was performed with propofol, rocuronium and general anesthesia was maintained with sevoflurane and remifentanil infusion. The mean arterial blood pressure was aimed to be <30% from baseline for controlled hypotension. Nicardipine infusion (1-5 µg/kg/min) was used in group N and Esmolol infusion (30-300 µg/kg/min) was used in group E. Surgical bleeding and surgical satisfaction, extubation and recovery time, postoperative side effects, antiemetic and additional analgesic medications were recorded. Results: There was no difference between the groups in demographic data, duration of anaesthesia, extubation time, recovery time, Aldrette recovery scores, and the use of antiemetic and additional analgesics. The NIRS values in N group were observed higher than E group at the 20th and 40th minutes on the left, and at the 25th, 30th, 35th, 40th, 45th and 60th minutes on the right (p<0.05). Mean arterial blood pressure at the 70th and 80th minutes, and heart rate at the 15th, 25th, 30th, 35th and 40th minutes were observed higher in N group when compared to the E group. In the esmolol group, it was observed mild bleeding in 23 patients, moderate bleeding in 7 patients. In the nicardipine group, it was observed mild bleeding in 11 patients, moderate bleeding in 18 patients, severe bleeding in 1 patient. Surgeon’s satisfaction was higher in the Esmolol group (p<0.05). Conclusion: It was concluded that both Nicardipine and Esmolol could be applied for controlled hypotension during the otologic surgery, cerebral oxygenation was maintained with at doses administered Nicardipine and Esmolol in sevoflurane-remifentanil anesthesia. Surgical bleeding was lesser and surgeon’s satisfaction was higher with the Esmolol group than the Nicardipine group.

Introduction: With aging of population, frailty and sarcopenia have become very important issues. Therefore, we aimed to evaluate patients for frailty and sarcopenia preoperatively who aged 65≤ underwent elective surgical operation in university hospital and search complications intraoperatively and postoperatively. Materials and Method: This prospective, cross-sectional study performed between November 2021 and May 2022 at university hospital and patients aged 65 years and older underwent elective surgery included. Patients scored with frailty index. Both thickness and cross-sectional area of rectus femoris muscle were measured by ultrasound for evaluating sarcopenia in all patients, preoperatively. Anesthetic management, surgical risks were determined. Intraoperative and postoperative complications recorded. Results: Totally 1112 patients were assessed and 279 patients were included. According to the cross-sectional area 35.5%; according to rectus femoris thickness 32.2% and according to both of them 25.4% were detected as sarcopenia. While fragility was detected in 151(54.7%) patients which 112(74.2%) pre-frail, 39(25.8%) fragile. 176(63.8%) patients experienced intraoperative complications. Postoperative complications were detected in 115(41.7%). The sarcopenia, frailty, and higher surgical risk classifications are increased intraoperative and postoperative complications (4.7, 4.1, 4 and 3.7, 6.4, 3.9 fold, respectively). Length of stay hospital (6.5 and 5 days) and intensive care unit (21 and 19 days), intraoperative (91.4% and 100%) and postoperative complication (81.4% and 87.2%) was higher sarcopenia and frailty (p<0.001). Conclusion: Intraoperative and postoperative complications were observed higher in frail and sarcopenic patients. Evaluation of frailty and sarcopenia in over 65 years at preoperative period can be helpful for prediction to risk of intraoperative and postoperative complications. Keywords: Intraoperative Complications; Frailty; Mortality; Postoperative Complications; Sarcopenia.

Purpose Laryngeal microsurgery is a challenging surgery because of the risk of airway complications. Therefore, extubation is of significant importance. We aimed to investigate the effect of magnesium sulfate on extubation quality, recovery features, and complications. Design A prospective, randomized, controlled clinical trial. Methods Ninety-eight adult patients scheduled for larynx laser microsurgery were included and randomly allocated to two groups to receive magnesium sulfate 30 mg/kg in 100 mL saline infusion (maximum 2 g) (group M) or saline 100 mL (group S) before induction of anesthesia. Anesthesia induction was performed with propofol 2 mg/kg, rocuronium 0.6 mg/kg, remifentanil 0.5 mcg/kg, and general anesthesia maintained with total intravenous anesthesia (propofol 3 to 7 mg/kg, remifentanil 0.05 to 0.1 mcg/kg/min, and O2/air 30/70 mixture). A train of four was used for neuromuscular monitoring. Extubation quality score, extubation time, postanesthesia care unit time, numerical rating scale, and complications were recorded. Findings Extubation quality scores were better in group M than group S (46 patients compared to 28 patients who had mild or no cough, P < .001, respectively). Extubation time was similar between groups. Postanesthesia care unit time was 15.7 ± 2.9 minutes in group M and 13.4 ± 4.6 minutes in group S, respectively (P = .01). Numerical rating scale scores were lower in group M than in group S (1 (1 to 2), 3 (2 to 3.5), respectively, P < .001). Conclusions Magnesium sulfate before induction of anesthesia resulted in better extubation quality scores without delayed recovery and positively affected postoperative analgesia.

Afet Durumlarında Rejyonel Anestezi Yönetimi Kıvanç ÖNCÜ Antikoagulan İlac Kullanan Hastalarda Noroaksiyel, Periferal ve Derin Sinir Blokları için Guvenli Aralık Sedat SAYLAN Ali AKDOĞAN Preeklampsili Hastada Anestezi Yönetimi Ali AKDOĞAN Engin ERTÜRK Postpartum Hemoraji ve Anestezi Yönetimi Özge ŞIKTAŞ Ortopedi Hastalarında Cerrahi Sonrası Hızlandırılmış İyileşme (ERAS) Protokolleri Demet LAFLI TUNAY Bolum 6 Malign Hipertermi ve Anestezi Yönetimi Murat TÜMER Rokuronyum İnfuzyonu İle Sağlanan Noromuskuler Bloğun Sugammadeks İle Geri Dondurulmesinin Desfluran veya Propofol Anestezisinde Karşılaştırmalı Değerlendirilmesi Necmiye ŞENGEL Gözde İNAN Mustafa ARSLAN

Objective: We aimed to to analyze the effect of the 3 different parenteral nutritions (MCT/LCT (long and midium chain fatty acids), LCT with omega-9 (ω-9) and MCT/LCT with ω-3 and ω-9 on the inflamatory cytokine levels in sepsis patients. This is the first study from the Southern part of Turkey. Patients and Methods: We included 30 patients, diagnosed with sepsis and took total parenteral nutrition in this study. Patients were divided into 3 randomized groups in terms of what parenteral nutrition have been taken. (Group A, B and C) Blood samples were taken and TNF-α, IL-1, IL-6 and IL-8 levels were evaluated. Adverse effects were recorded. TNF-α, IL-1β, IL-6, and IL-8 levels of were analyzed by ELISA method and each sample were studied in dublicate. Results: The median age of the patients included in the study was 52 and 24 (80%) of them were male. The SOFA score was 5 in study group. We examined IL-1, IL-6, IL-8 and TNF-α distribution on the day of the first, third and fifth days depending on time. The inflamatory cytokine levels were not found statistically significant (p > 0.05) when we compared the study groups via 3 different parenteral nutritions. Conclusion: When we compare MCT/LCT, LCT/ω-9 and MCT/LCT, ω-3, ω-9 which are given as a component of total parenteral nutrition we concluded that there was no superiority to others in terms of proinflamatory cytokin levels in sepsis and they didn’t increase proinflamatory cytokins. There is a need for more randomized controlled studies investigating the effect of lipids on the course of the disease in sepsis patients who cannot receive enteral nutrition and require TPN support.

BACKGROUND:Endotracheal intubation is a frequently performed procedure in anesthesia practice, and ensuring the correct inflation of the cuff is essential for maintaining the airway seal. Overinflation of endotracheal tube (ETT) cuffs can lead to complications, such as postoperative sore throat. This study aimed to compare the incidence of elevated ETT cuff pressure between saline and air inflation in elective laparoscopic abdominal surgery. METHODS:The study involved 60 participants ranging in age from 18 to 65, with American Society of Anesthesiologists physical status levels 1-2, who underwent laparoscopic abdominal surgery. We randomly assigned patients to two groups: Group A (air-filled ETT cuffs, N.=30) and Group S (saline-filled ETT cuffs, N.=30). Intra-cuff pressure was recorded before and after CO2 insufflation, as well as during changes in patient position. The number of interventions to restore intra-cuff pressure to 18 mmHg was documented. Peak airway pressure, plateau pressure, and positive end-expiratory pressure (PEEP) were measured at 15-minute intervals. RESULTS:The number of interventions needed to maintain intra-cuff pressure was significantly lower in the saline group compared to the air group. All patients started with initial cuff pressures above 20 mmHg. After insufflation, the first-minute cuff pressures were higher in the air group (P=0.001). Both groups experienced a significant increase in intra-cuff pressure with the Trendelenburg position, and after moving to the reverse Trendelenburg position (saline and air groups, P=0.001 and 0.012, respectively), the air group had higher intra-cuff pressure than the saline group (P=0.002). There were no significant differences between groups in peak airway pressure, plateau pressure, and PEEP. CONCLUSIONS:Inflating ETT cuffs with saline instead of air during laparoscopic abdominal surgeries led to a reduced requirement for interventions in maintaining pressure. This indicates that the use of saline inflation may significantly lower the risk of high cuff pressure and related complications.

Objective: Different drugs or methods can be applied to provide brain relaxation in supratentorial tumor surgery. In our study, we aimed to evaluate effects of 20% Mannitol and 3% Hypertonic Saline (HS) used during supratentorial tumor surgery on brain relaxation, hemodynamic parameters, urine flow, fluid volume, pulse pressure variability (PPV), pleth variability index (PVI), serum osmolarity and electrolytes. Methods: The study included 60 patients aged 18-65 years, ASA I-II class, who were scheduled to undergo supratentorial tumor surgery. General anesthesia was administered with sevoflurane and remifentanil to achieve a state entropy of 40-60. Patients were allocated into two groups, with Group Mannitol receiving 20% mannitol (2.5 mL kg-1) and Group Hypertonic Saline receiving 3% HS (2.5 mL kg-1). In all patients, PPV and PVI values were planned to be ≤13%. After the dura was opened, brain relaxation scores were evaluated. Perioperative hemodynamic variables, blood gases, PVI, PPV values were recorded. Na+, K+ values, urine volume and administered fluid were recorded at 30, 45 and 60 minutes and 2-3 hours after the end of the infusion. Preoperative and postoperative BUN, creatinine and osmolarity values were recorded. Results: No statistical difference was found between demographic characteristics, brain relaxation and hemodynamic data. In HS group, PVI and PPV values were higher than Mannitol group from the beginning of infusion. In mannitol group, urine and administered fluid amounts were higher. Decrease in Na+ values was detected with Mannitol and increase with HS. It was determined that BUN and creatinine values were similar, serum osmolarity did not change at postoperative period in mannitol group and increased HS. Average intensive care and length of hospital stay were similar. Conclusion: In supratentorial tumor surgery, effective brain relaxation was achieved with Mannitol and HS, without affect to hemodynamics. Pulse pressure variability and PVI decreased with Mannitol. Blood gases, Na+, K+, BUN creatinine, osmolarity levels did not show serious changes. It was concluded that HS could be an alternative to mannitol in supratentorial surgery. Keywords: Hypertonic saline,mannitol, serum osmolarity, supratentorial tumor surgery

OBJECTIVE:The authors aimed to compare the anti-inflammatory and antioxidant effects of propofol and sevoflurane in children with cyanotic congenital heart disease (CCHD) undergoing cardiac surgery with cardiopulmonary bypass.DESIGN:Prospective, randomized, double-blind study.SETTING:Single center, university hospital.PARTICIPANTS:Children ages 1-10 years with CCHD undergoing elective cardiac surgery with cardiopulmonary bypass.INTERVENTIONS:Children were randomized to receive general anesthesia with either sevoflurane (group S) or propofol (group P). Systemic inflammatory response syndrome (SIRS) occurrence was assessed at the end of the surgery and at the sixth, 12th, and 24th postoperative hours. Blood samples were obtained at 4 times: after anesthesia induction (T0), after release of the aortic cross-clamp (T1), at the end of the surgery (T2), and at the postoperative 24th hour (T3). The serum levels of interleukin 6 and tumor necrosis factor alpha, and the total antioxidant status (TAS) and total oxidant status, were analyzed.RESULTS:SIRS was more common in group S than in group P at all times (p = 0.020, p = 0.036, p = 0.004, p = 0.008). There were no significant differences between the groups in the mean tumor necrosis factor alpha and interleukin 6 levels at any time. The TAS level at T2 was higher in group P than group S (p = 0.036). The serum TAS level increased at T2 compared with T0 in group P, but it decreased in group S (p = 0.041).CONCLUSION:The results showed that propofol provided a greater antioxidant effect and reduced SIRS postoperatively more than sevoflurane in children with CCHD undergoing cardiac surgery.

Ultrasound-guided erector spinae plane block (ESPB) is an interfascial plane block used for analgesia of the chest and abdominal wall. This study aimed to evaluate the perioperative analgesic efficacy of bilateral single-shot ESPB at T5 vertebral level in breast reduction surgery. Sixty adult female patients scheduled for breast reduction surgery were included and randomly allocated to two groups to receive either preoperative ESPB with a local anesthetic mixture of 10 mL 0.5 www.springer.com/00266 .

Akademisyen Yayınevi yöneticileri, yaklaşık 30 yıllık yayın tecrübesini, kendi tüzel kişiliklerine aktararak uzun zamandan beri, ticarî faaliyetlerini sürdürmektedir. Anılan süre içinde, başta sağlık ve sosyal bilimler, kültürel ve sanatsal konular dahil 2700'ü aşkın kitabı yayımlamanın gururu içindedir. Uluslararası yayınevi olmanın alt yapısını tamamlayan Akademisyen, Türkçe ve yabancı dillerde yayın yapmanın yanında, küresel bir marka yaratmanın peşindedir. Bilimsel ve düşünsel çalışmaların kalıcı belgeleri sayılan kitaplar, bilgi kayıt ortamı olarak yüzlerce yılın tanıklarıdır. Matbaanın icadıyla varoluşunu sağlam temellere oturtan kitabın geleceği, her ne kadar yeni buluşların yörüngesine taşınmış olsa da, daha uzun süre hayatımızda yer edineceği muhakkaktır.

Giriş: Cerrahi hastalarda bilinen COVID-19 enfeksiyonu olmasa dahi pandemi sürecinde postoperatif morbidite ve mortalitenin artığı bilinmektedir. Bu çalışma ile, 2019 Eylül - 2020 Eylül tarihleri arasında sezaryen (C/S) ameliyatına alınan gebeler, pandemi öncesi ve sonrası olmak üzere iki ayrı grupta ele alınarak pandemi döneminin anestezi tercihi ile anne ve bebekle ilgili sonuçlar üzerine etkileri değerlendirilmek istenmiştir. Gereç ve Yöntemler: Bu çalışmada üçüncü basamak bir hastanede bir yıllık deneyim kapsamında sezaryen ameliyatına alınan gebeler, COVID-19 pandemisi öncesi ve sonrası olmak üzere iki ayrı dönemde retrospektif olarak incelendi. Çalışmanın birincil sonuç ölçütü, pandemi döneminde C/S operasyonlarındaki rejyonel anestezi uygulanma oranları idi. Bulgular: 1241 C/S olgusunun analiz edildiği bu çalışmanın sonuçlarına göre, anne yaşı, gebelik haftası, gravida, gebelikle ilgili morbiditeler, APGAR skoru dahil yenidoğana ait veriler ve C/S cerrahisi endikasyonları erken COVID-19 pandemisi döneminde değişikliğe uğramamıştır. Ancak anneye ait anemi dahil ek hastalık oranı, yenidoğan yoğun bakıma yatış oranı ve hastanede kalış süresi pandemic döneminde öncesine göre azalmış; rejyonel anestezi uygulamaları ve postoperatif maternal komplikasyon oranları ise artmıştır. Sonuç: Bu çalışmada, obstetrik anesteziye dair gerek klinik uygulamalarda gerekse hasta sonuçlarında COVID-19 pandemisi dönemi ile birlikte çeşitli değişikliklerin ortaya çıktığı gözlenmiştir. Anahtar Kelimeler: Sezaryen, COVID-19, obstetrik anestezi, pandemi.