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20222023

论文（3）

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1Investigation of cadmium contamination in wheat flour and assessment on dietary exposure in Shandong Province

YANG Yonghao,DONG Wenya,LIU Jing,CHU Zunhua,ZHAO Jinshan,ZHAO Xiulan,XIAO Peirui

Objective This study was designed to investigate cadmium(Cd)pollution levels in wheat and wheat flour in different cities of Shandong Province,as well as conduct preliminary health risk assessment of Cd intake via wheat flour.Methods 1 789 samples of wheat or wheat flour were collected from farmers'markets,supermarkets,and farmers in 16 cities of Shandong Province.Inductively coupled plasma-mass spectrometry(ICP-MS)was performed to determine the Cd content in wheat.Based on the data of residents'wheat flour consumption,the risk of Cd exposure of residents through wheat flour was estimated.Results The Cd level of wheat was higher than that of wheat flour(Z=-12.50,P＜0.001),and there were differences among cities in Cd levels in both wheat and wheat flours.The estimated monthly intake(EMI)of the average consumer group in Shandong Province was 1.18 μg/kg·BW,accounting for 4.72％of the provisional tolerable monthly intake(PTMI).The EMI of the high-consumption population of wheat flour was 2.87 μg/kg·BW,accounting for 11.47％ of the PTMI.Conclusion The exposure risk of dietary Cd from wheat flour in the average consumer population of Shandong Province is low;however,further attention should be paid to the exposure risk to dietary Cd in high wheat-flour consumers in cities with relatively high Cd content.

2023Zhongguo shipin weisheng zazhi（2023）

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2Contamination status and dietary exposure assessment of aflatoxin B1 in peanut and its products sold in Shandong province

DONG Wenya, CHEN Chen,ZHAO Xiulan, YANG Yonghao,ZHAO Jinshan,XIAO Peirui,CHU Zunhua

为了解山东省市售花生及其制品中黄曲霉毒素B1(AFB1)污染状况,评估其暴露水平及潜在的健康风险,并为有关部门采取控制措施提供依据,2015-2020年于山东省16市生产环节、流通环节(农贸市场、商店)随机采集花生、花生酱、花生油共计246份样品,采用高效液相色谱-柱后衍生法测定其AFB1含量,计算AFB1平均膳食暴露量和暴露限值(MOE),评估山东省市售花生及其制品中AFB1膳食暴露风险.结果表明,花生及其制品中AFB1总检出率为28.46％,不合格率为7.72％.花生酱和花生油中AFB1检出率显著高于花生;散装花生酱、花生油中AFB1检出率显著高于预包装产品;一般消费居民通过花生、花生酱和花生油AFB1平均膳食暴露量分别为0.01、0.61、1.09 ng/(kg·d),肝癌发病风险分别为0.000、0.019、0.034例/10万人,其MOE分别为30 500、500和280;高消费居民通过花生、花生酱和花生油AFB1平均膳食暴露量分别为0.23、6.64、8.90 ng/(kg·d),肝癌发病风险分别为0.007、0.205、0.274例/10万人,其MOE分别为1 326、46和34.严格执行限量标准后经花生酱和花生油AFB1平均膳食暴露量、肝癌发病风险降幅均达50％以上.为了更大限度地保护人群健康,有必要采取有效的监管和风险管理措施控制山东省市售花生及其制品中AFB1含量,特别是散装花生酱和花生油.

2023China Oils and Fats（2023）引用：1

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3Effects of Aflatoxin on Growth Retardation in Children

DONG Wenya

黄曲霉毒素是一种由黄曲霉和寄生曲霉代谢产生的有毒次级代谢物,易对粮食及其制品造成污染.长期食用受黄曲霉毒素污染的食物与儿童生长迟缓存在关联,本文总结了大量的动物实验和流行病学研究,分析了黄曲霉毒素暴露与儿童生长迟缓的关系以及对人类健康的相关影响,为黄曲霉毒素的防控提供依据.

2022China Food Safety Magazine（2022）

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