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11431: Coretherm Treatment Vs Turp in Patients with BPH: A Prospective Randomized Multicenter Study with 5 Years Follow-Up

A Mattiasson,S Schelin, B Magnusson,M Schain,H Ageheim,J Richthoff,J Duelund,K Kroyer,J Nordling,E Boyle,T Larson,L Wagrell

You have accessJournal of UrologyPodium, Tuesday, May 23, 2006, 3:30 - 5:30 pm1 Apr 20061431: Coretherm Treatment vs Turp in Patients with BPH: A Prospective Randomized Multicenter Study with 5 Years Follow-Up Anders Mattiasson, Sonny Schelin, Kalmar, Magnusson, Moddy Schain, Hakan Ageheim, Jonas Richthoff, Jens Duelund, Kurt Kroyer, Jergen Nordling, Emmet Boyle, Thayne Larson, and Lennart Wagrell Anders MattiassonAnders Mattiasson More articles by this author , Sonny SchelinSonny Schelin More articles by this author , Kalmar Kalmar More articles by this author , Magnusson Magnusson More articles by this author , Moddy SchainModdy Schain More articles by this author , Hakan AgeheimHakan Ageheim More articles by this author , Jonas RichthoffJonas Richthoff More articles by this author , Jens DuelundJens Duelund More articles by this author , Kurt KroyerKurt Kroyer More articles by this author , Jergen NordlingJergen Nordling More articles by this author , Emmet BoyleEmmet Boyle More articles by this author , Thayne LarsonThayne Larson More articles by this author , and Lennart WagrellLennart Wagrell More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)33635-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1431: Coretherm Treatment vs Turp in Patients with BPH: A Prospective Randomized Multicenter Study with 5 Years Follow-Up." The Journal of Urology, 175(4S), p. 462 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 462 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Anders Mattiasson More articles by this author Sonny Schelin More articles by this author Kalmar More articles by this author Magnusson More articles by this author Moddy Schain More articles by this author Hakan Ageheim More articles by this author Jonas Richthoff More articles by this author Jens Duelund More articles by this author Kurt Kroyer More articles by this author Jergen Nordling More articles by this author Emmet Boyle More articles by this author Thayne Larson More articles by this author Lennart Wagrell More articles by this author Expand All Advertisement PDF downloadLoading ...

2006JOURNAL OF UROLOGY（2006）

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2CORETHERM® TREATMENT VS. TURP IN PATIENTS WITH BPH: A PROSPECTIVE RANDOMISED MULTICENTRE STUDY WITH 5-YEAR FOLLOW-UP

A. Mattiasson,S. Schelin, B. Magnusson, S. Moddy,H. Ageheim,J. Richthoff,J. Duelund,K. Kröyer, J. Nordlig,E. Boyle,T. Larson

2006European Urology Supplements（2006）引用：2

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3ProstaLund microwave Feedback Treatment compared with TURP for treatment of BHP; A prospective randomized multicenter study with 24 months folllow up

L Wagrell,S Schelin,J Nordling,J Richthoff, B Magnusson,M Schain,T Larson,E Boyle,J Duelund,K Kroyer,H Ageheim,A Mattiasson

2003JOURNAL OF UROLOGY（2003）

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4Feedback Microwave Thermotherapy Versus TURP for Clinical BPH--a Randomized Controlled Multicenter Study.

L Wagrell,S Schelin,J Nordling,J Richthoff,B Magnusson,M Schain,T Larson,E Boyle,J Duelund,K Kroyer,H Ageheim,A Mattiasson

Objectives To compare, in a prospective randomized multicenter study, the efficacy and safety of transurethral microwave thermotherapy with ProstaLund Feedback Treatment (PLFT), using the CoreTherm device, with transurethral resection of the prostate (TURP) 36 months after treatment. Methods The study was conducted at 10 centers in the United States and Scandinavia. A total of 154 patients with benign prostatic hyperplasia were randomized to PLFT or TURP in a 2:1 ratio. The treatment outcome was evaluated on the basis of the International Prostate Symptom Score (IPSS), the quality-of-life question (QOL) of the IPSS, peak urinary flow rate (Qmax), urodynamics, and adverse events. The microwave power and treatment time were adjusted according to each patient's response to the supplied energy (ie, the intraprostatic temperature guided the PLFT). Results Statistically significant improvements in both the TURP and the PLFT groups were observed for IPSS, QOL, and Qmax at 36 months. The average value for the PLFT group was 8.2, 1.2, and 11.9 mL/s for IPSS, QOL, and Qmax, respectively. The corresponding values for the TURP group were IPSS 5.0, QOL 1.0, and Qmax 13.5 mL/s. The difference in IPSS outcome was statistically significant; however, no statistically significant differences were found in QOL or Qmax between the two treatment groups. The degree of improvement was in the same range as that observed after 12 and 24 months for both groups. During the 12 to 36-month period, the most frequent adverse events in the TURP group were impotence (15%), micturition urgency (13%), and urethral disorder (8%); in the PLFT group, impotence (8%), prostate-specific antigen increase (5%), and hematuria (4%) were the most common. Conclusions The clinical outcome 3 years after microwave thermotherapy with PLFT was comparable to the results seen after TURP. The safety of PLFT compared favorably to that of TURP in this study.

2002Urology（2002）引用：85

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