When the tail fractions from chromatograms of sporidesmin E(I; n= 3) were rechromatographed, a new crystalline metabolite of Pithomyces chartarum was isolated with molecular formula C18H20ClN3O6S4. The new compound, named, sporidesmin G (I; n= 4), gave sporidesmin (I; n= 2) on irradiation or treatment with triphenylphosphine, and sporidesmin D (V) after reduction and methylation. It was shown that the model compound, 1,4-dimethyl-3,6-epidithiopiperazine-2,5-dione, gave the cyclic tetrasulphide on treatment with dihydrogen disulphide. Similarly, sporidesmin and sporidesmin E when treated with dihydrogen disulphide gave the new metabolite.

Chemischer InformationsdienstVolume 3, Issue 18 Heterocyclic Compounds ChemInform Abstract: SPORIDESMINE 12. MITT. ISOLIERUNG UND STRUKTUR VON SPORIDESMIN G, EINEM NATUERLICH VORKOMMENDEN 3,6-EPITETRATHIO-PIPERAZINDION-(2,5) E. FRANCIS, E. FRANCISSearch for more papers by this authorR. RAHMAN, R. RAHMANSearch for more papers by this authorS. SAFE, S. SAFESearch for more papers by this authorA. TAYLOR, A. TAYLORSearch for more papers by this author E. FRANCIS, E. FRANCISSearch for more papers by this authorR. RAHMAN, R. RAHMANSearch for more papers by this authorS. SAFE, S. SAFESearch for more papers by this authorA. TAYLOR, A. TAYLORSearch for more papers by this author First published: May 2, 1972 https://doi.org/10.1002/chin.197218333AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume3, Issue18May 2, 1972 RelatedInformation