We report on a 15-year-old boy suffering from acute morbus moniliformis. To the best of our knowledge, this cutaneous eruption in its acute form has not been described before. We think that morbus moniliformis is a unique dermatosis different from keratosis lichenoides chronica or lichen planus.

Journal Article Induction of pemphigus by X‐ray irradiation Get access M. DAVID, M. DAVID Department of Dermatology, Beilinson Medical Center, Petah Tikva, and the Sackler School of Medicine, Tel Aviv University, Israel Dr M. David, Department of Dermatology, Beilinson Medical Center, Petah Tikva, Israel 49 100. Search for other works by this author on: Oxford Academic Google Scholar E.J. FEUERMAN E.J. FEUERMAN Department of Dermatology, Beilinson Medical Center, Petah Tikva, and the Sackler School of Medicine, Tel Aviv University, Israel Search for other works by this author on: Oxford Academic Google Scholar Clinical and Experimental Dermatology, Volume 12, Issue 3, 1 May 1987, Pages 197–199, https://doi.org/10.1111/j.1365-2230.1987.tb01894.x Published: 01 May 1987 Article history Accepted: 14 November 1986 Published: 01 May 1987

During a period of 8 years 300 cases of dermatophytoses involving both hairy areas and the glabrous skin were found to be caused by M. canis. There was scalp involvement in 60%, including 8 infants and 27 adults; most of the adults presented Kerion-like lesions and presented various clinical aspects such as seborrhea capitis, folliculitis and discois lupus erythematosus. In the 21 patients showing invasion of the beard the clinical manifestations included superficial erythematosquamous patches with hyperemic slightly elevated margins, folliculitis or abscess-like lesions and Kerion-like lesions. Among the lesions found on the glabrous skin there were unusual aspects of tinea faciei in 19 adults, mimicking lymphocytic infiltration, granuloma faciale or discoid lupus erythematosus. Some of the cases of tinea corporis found in 70 patients also had lesions simulating various other dermatological entities, including erythema multiforme, psoriasiform eruption, pityriasis rosea and seborrheic dermatitis. The hands were invaded in 5 adults patients, with involvement of the finger nails in one. Repeated mycologic examinations were necessary to establish the true etiology in many of these cases.

We report on two typical cases of lichen planus and lichen pigmentosus appearing after gold therapy. The characteristics of lichen planus induced by drugs are emphasized, and the literature is reviewed.

The case of a lichenoid photosensitive eruption induced by hydrochlorothiazide is described. The macrophage migration inhibition factor test identified hydrochlorothiazide as the offending drug out of the several suspected drugs taken by the patient. It is suggested that an allergic reaction towards hydrochlorothiazide was involved in the development of the photosensitive lichenoid eruption in this case.

A second case of actinomycetoma due to Nocardia caviae contracted in Israel is reported. A 39-year-old female of Yemenite origin, resident in Israel for more than 15 years, presented with a sclerotic tumor mass on the dorsum of the right foot which discharged an oily purulent fluid containing minute yellowish granules. Seen in the microscopic examination of smears were thin Gram-positive filaments and bacillary elements. Culture of the crushed granules yielded small pale colonies identified as Nocardia caviae. In vitro testing of the isolate to various antibiotics, isoniaside and sulphonamides showed the organism to be more sensitive to isoniaside and tetracycline. Isoniaside was administered for one year with marked improvement and was then replaced by tetracycline due to side effects, this treatment still being continued.

ABSTRACT: Five patients had a form of pemphigus which in its early stages resembled dermatitis herpetiform, although the immunofluorescent findings were typical of pemphigus, Potassium iodide tests, performed for the first time In such patients, showed positive results in two patients. Follow‐ups ranging from 5 to 14 years have shown a benign course with low to absent dosages of steroids

T-lymphocyte number and function as well as the effect of a thymic hormone on the T-suppressor cell subset were studied in 22 children suffering from psoriasis vulgaris, subdivided into two groups, those with less than 20% of total skin area involved and those with more than 20% of involvement. The T-cell number was lower in the latter group than it was in the first group or in normal controls. There was no significant difference in the functional activity of T cells in the two groups of patients. The number of T-suppressor cells was significantly lower in the psoriatic children than in normal controls, being lowest in the children showing greater skin involvement. THF, a thymic hormone isolated from calves, was found in vitro to induce T-suppressor cells in the peripheral blood of the psoriatic children, suggesting that this hormone may be able to play a role in the treatment of this disease.

Cowden's disease was diagnosed in three siblings (two sisters and a brother) in a Jewish Israeli family of Yemenite origin. The typical mucocutaneous lesions of the disease were present in all three cases. There were hamartomas involving other body systems, including euthyroid multinodular goiter (in all 3 cases), gastrointestinal polyposis (in 2 cases) and hemangioma (in one case). Developmental anomalies were found in all 3 cases. Histological examination of mucocutaneous lesions was in accordance with previous descriptions, including the findings compatible with trichilemmoma observed in cutaneous facial papules. Extensive electron-microscope studies of these facial lesions yielded no evidence of viral particles. Immunological studies, carried out mainly in two cases, revealed a decrease in complement level in the serum and impairment of T cell function.

The coexistence of psoriasis vulgaris and bullous diseases has been described in the literature, mainly with bullous pemphigoid. In the majority of cases the bullous eruption has been thought to be related to antipsoriatic treatment. We describe nine cases of psoriasis vulgaris that were associated with bullous diseases: five bullous pemphigoid, one cicatricial pemphigoid, and three pemphigus vulgaris. The association between psoriasis vulgaris and these bullous diseases may be explained on an immunologic basis.

International Journal of DermatologyVolume 24, Issue 1 p. 359-361 The Sign of Leser-Trélat A Cutaneous Marker for Internal Malignancy Sima Hai.evy M.D., Corresponding Author Sima Hai.evy M.D. Department of Dermatology, Beilinson Medical Center, Petah Tikva, and the Sackler School of Medical Tel Aviv University, Tel Aviv, IsraelAddress for correspondence: Sima Halevy, M.K., Department of Dermatology, Beilinson medical Center, Petah Tikva, Israel 49 100Search for more papers by this authorEleasar J. Feuerman M.D., Eleasar J. Feuerman M.D. Department of Dermatology, Beilinson Medical Center, Petah Tikva, and the Sackler School of Medical Tel Aviv University, Tel Aviv, IsraelSearch for more papers by this author Sima Hai.evy M.D., Corresponding Author Sima Hai.evy M.D. Department of Dermatology, Beilinson Medical Center, Petah Tikva, and the Sackler School of Medical Tel Aviv University, Tel Aviv, IsraelAddress for correspondence: Sima Halevy, M.K., Department of Dermatology, Beilinson medical Center, Petah Tikva, Israel 49 100Search for more papers by this authorEleasar J. Feuerman M.D., Eleasar J. Feuerman M.D. Department of Dermatology, Beilinson Medical Center, Petah Tikva, and the Sackler School of Medical Tel Aviv University, Tel Aviv, IsraelSearch for more papers by this author First published: January 1985 https://doi.org/10.1111/j.1365-4362.1985.tb05498.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Volume24, Issue1January 1985Pages 359-361 RelatedInformation

A psoriatic patient who developed cicatricial pemphigoid and leiomyosarcoma of the abdomen is presented. The sequence of events indicates a relationship between the cicatricial pemphigoid and the malignant disease.