OBJECTIVES:Tricuspid regurgitation (TR) is commonly encountered in patients with left-sided valve disease and often progresses postoperatively if left unaddressed. While mitral valve replacement (MVR) alone may improve left heart parameters, concomitant tricuspid ring annuloplasty (TRA) might prevent right-sided deterioration. METHODS:This retrospective study analysed 129 patients undergoing MVR between 2016 and 2019. Patients were divided into 2 groups: isolated MVR (n = 71) and MVR + TRA (n = 58). Long-term echocardiographic outcomes were compared, including LVDD, LVSD, LVEF, LA diameter, IVS thickness, pulmonary flow rate, PAP, and TI degree. RESULTS:Both the groups showed regression in left heart dimensions postoperatively; however, left ventricular ejection fraction (LVEF) significantly decreased in the MVR-only group (P < .001) while it remained stable in the MVR + TRA group (P =0.598). Severe tricuspid insufficiency occurred in 12% (95% CI 5%-21%) of patients undergoing isolated MVR and 0% (95% CI 0%-6 ) of those undergoing MVR + TRA (P < .001). The mean difference in the change of pulmonary artery pressure (ΔPAP) between the groups was 12.0 mmHg (95% CI 6.5-17.3, P = .002), and both pulmonary artery pressure and left atrial diameter significantly decreased postoperatively in the MVR + TRA group. CONCLUSIONS:Performing TRA during MVR surgery offers significant protective effects against TI progression and right heart overload. Even in cases with mild TI but annular dilation, simultaneous TRA may be a rational and beneficial strategy to ensure long-term cardiac stability.
OBJECTIVE: Varicose veins are usually seen in the legs and cause pain, tingling and aesthetic problems. In patients diagnosed with venous insufficiency, many comorbid conditions such as smartphone addiction that impair the quality of life are detected. The objective of this study was to investigate the association between smartphone addiction and venous insufficiency. MATERIAL AND METHODS: The study included 350 patients who applied to the Cardiovascular Surgery clinic with complaints of leg pain and tingling and were diagnosed with venous insufficiency. The Turkish version of the Smartphone Addiction Scale (SAS) was applied to the patients. The patients who were evaluated for venous insufficiency with lower extremity venous doppler were classified from C1 to C6 according to the Clinical-Etiology-Anatomy-Pathophysiology (CEAP) classification. The patients' scores from the scales were compared among themselves. RESULTS: A total of 96 (21.7%) male patients and 254 (78.3%) female patients were included in the study. Their ages ranged from 25 to 84 years, and the mean age was 46.88±14.4 years. The mean Smartphone Addiction Scale (SAS) score of the patients participating in the study was determined as 46.94 (±30.68). CONCLUSIONS: Venous insufficiency is a common condition. The presence of smartphone addiction has been demonstrated to have a correlative relationship with an increased degree of venous insufficiency. However, our study should be supported by further studies.
The second-to-fourth digit ratio (2D:4D) has been explored as a marker of prenatal hormonal exposure, but its association with left main coronary artery (LMCA) stenosis, particularly in women, remains unclear. This prospective observational study included 400 patients undergoing coronary angiography and cardiac surgery. Right- and left-hand 2D:4D ratios were measured, and LMCA stenosis was assessed angiographically. Exploratory analyses evaluated potential associations between right-hand 2D:4D ratios and selected postoperative outcomes, including intensive care unit length of stay and acute kidney injury. Female patients were further stratified according to LMCA stenosis (< 50
OBJECTIVE:A variety of cardioplegia techniques with different components are implemented to ensure myocardial protection, in addition to keeping the operationa field immobile and free of blood during cardiac surgery. The implemented cardioplegia has unwanted negative effects on other end organs. In this study, our aim was to compare the effects of Del Nido cardioplegia and blood cardioplegia solutions on postoperative intensive care duration, drainage, and renal functions for patients undergoing cardiopulmonary bypass and bypass graft operations. METHODS:Selections were made from patients undergoing elective bypass graft operations in our clinic from January 1, 2022 to December 31, 2023. Patients were randomly selected, retrospectively assessed, and divided into two groups - De Nido group (Group 1) and blood cardioplegia group (Group 2). Comparisons were made between these groups in terms of intensive care duration, drainage, and renal functions. RESULTS:The study included 120 patients. The Del Nido cardioplegia group included 60 patients, with 60 patients in the blood cardioplegia group. Comparisons between the groups found that the aortic cross-clamping duration was significantly high in Group 1 (P = 0.014). The noradrenaline dose given to Group 1 was high (P = 0.004). In terms of renal injury, significant degree of elevation was present in Group 1 (P = 0.027). The longer aortic cross-clamping duration in Group 1 may be assessed as a determinant factor for noradrenaline dose and acute kidney injury. CONCLUSION:This study concluded that it willbe appropriate to choose the cardioplegia method by performing broader meta-analysis studies and minimizing limiting factors.
OBJECTIVE The aim of this study was to investigate postoperative left ventricular changes [left ventricular mass (LVM), left ventricular mass index (LVMI), left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), patient-prosthesis mismatch (PPM), pulmonary artery pressure (PAP), gradients, and ejection fraction (EF)] according to the valve type used in patients undergoing aortic valve replacement (AVR) due to isolated aortic stenosis. METHODS A total of 199 patients with isolated AVR due to aortic stenosis between 2010 and 2020 was retrospectively investigated. Four groups were identified according to the valve type used (mechanical, bovine pericardium, porcine and sutureless). Pre-operative and first year postoperative transthoracic echocardiography findings for the patients were compared. RESULTS Mean age was 64.4 ± 13.0 years, while the gender distribution was 41.7% women and 58.3% men. Of the valves used in patients, 39.2% were mechanical, 18.1% were porcine, 8.5% were bovine pericardial and 34.2% were sutureless valves. Analysis independent of the valve groups observed LVEDD, LVESD, maximum gradient, mean gradient, PAP, LVM and LVMI values reduced significantly postoperatively (p < 0.001). EF was observed to increase by 2.1% (p = 0.008). Comparisons of the four valve groups revealed that LVEDD, LVESD, maximum gradient, mean gradient, LVM and LVMI significantly decreased in all groups. EF significantly increased only in the sutureless valve group (p = 0.006). Analysis of PPM groups showed that LVESD, maximum gradient, mean gradient, PAP, LVM and LVMI were significantly reduced in all groups. In the normal PPM group, there was an improvement in EF, which was significantly different to the other groups (p = 0.001), while in the severe PPM group, EF appeared to be reduced ( p = 0.19).
Amaç: Seruloplazmin, kanda bakır taşıyan başlıca proteindir ve demir metabolizmasında da rol oynar. Ayrıca antioksidan aktivitesi birçok çalışmada gösterilmiştir. Bu çalışmada koroner arter baypas greft operasyonu ile seruloplazminin enzimatik aktivite düzeyleri arasındaki ilişkiyi araştırdık. Gereç ve Yöntemler: Çalışmaya koroner arter baypas greft operasyonu geçiren 120 hasta dahil edildi. Periferik kan örnekleri ameliyat öncesi, ameliyat sonrası - kardiyopulmoner baypas öncesi ve sonrası-, ameliyat sonrası 4. saat, 3. gün ve 5. gün alındı. Koroner sinüsten de kardiyopulmoner baypas öncesi ve sonrası kan örnekleri alındı. Seruloplazmin düzeylerinin enzimatik aktivitesi Erel yöntemi ile ölçüldü. Bulgular: Kardiyopulmoner baypas sonrası seruloplazmin düzeylerinin enzimatik aktivitesinde kademeli bir azalma oldu. Postoperatif 4. saat ve 1. gün periferden alınan kan örneklerinde azalma istatistiksel olarak anlamlıydı (p = 0,025). Aktiviteler sırasıyla postoperatif 3. ve 5. günlerde arttı. Koroner sinüs kan örneklerine göre de, kardiyopulmoner baypas sonrası seruloplazmin enzimatik aktivitesinde önemli bir azalma vardı (p = 0.035). Sonuç: Çalışmamız, seruloplazmin enzimatik aktivitesinin preoperatif, peroperatif ve postoperatif düzeylerinde önemli farklılıklar gösterdi. Muhtemelen oksidan aktiviteye yanıt olarak tüketime bağlı olan postoperatif 3. gündeki azalma, kardiyovasküler baypasın oksidatif stresi önemli ölçüde artırdığını göstermiştir. Seruloplazmin enzimatik aktivitesi, kardiyopulmoner baypas ile ilişkili enflamatuar ve oksidatif stresin tepkisini yansıtan parametrelerden biri olabilir.
Aortic coarctation is a congenital vascular lesion, usually diagnosed and corrected in childhood or early adulthood. Most of the untreated patients with aortic coarctation die before the age of 50 years. Coarctation with cardiac lesions is a complex clinical situation that necessitates surgical treatment of different pathologies with different strategies. In this, study we report two-staged surgical treatment of aortic coarctation with severe aortic stenosis consist of aortic valve replacement and aorto-subclavian bypass in a 63-year-old male patient.
Aim: The relationship between inflammation and the development of atrial fibrillation and the relationship between platelet to lymphocyte ratio and mean platelet volume in relation to inflammation were investigated in patients with atrial fibrillation after isolated coronary artery bypass graft operation. Material And Methods: Clinical and laboratory data of 132 patients, who did not have preoperative atrial fibrillation and underwent isolated coronary artery bypass graft operation using cardiopulmonary pump, were analyzed retrospectively. Patients were divided into two groups as patients with developed atrial fibrillation and those without atrial fibrillation. Concomitant diseases, preoperative drug use, echocardiographic and angiographic findings, preoperative, intraoperative and postoperative laboratory parameters were obtained from medical records and compared statistically. Results: Of the 132 patients, 68 with atrial fibrillation (mean age: 68.3+/-10.7 years, 50 males and 18 females) and 64 patients without atrial fibrillation (mean age: 64.5+/-9.8 years, 55 males and 9 females) were identified, and difference in the mean age was statistically significant (p=0.016). Postoperative platelet to lymphocyte ratio and mean platelet volume values (280.3+/-112.3; 9.9+/-1.7) were also significantly higher in those with atrial fibrillation group than preoperative values (129.2+/-49.3; 9.6+/-1.6, p<0.0001, p<0.0009). Conclusıon: According to our study higher values of postoperative platelet to lymphocyte ratio and mean platelet volume are correlated with development of atrial fibrillation after coronary artery bypass graft operation.
Giriş-Amaç: Pulmoner emboli vakaları tedavi edilmediği takdirde ani ölüm, hayatı tehdit eden akut bir durum ya da trombüslerin pulmoner damar duvarında organize olmasına bağlı olarak kronik tromboembolik pulmoner hipertansiyon gelişir. Bu çalışmada, tüm dünyada belirli merkezler dışında çok fazla sayıda yapılmayan ve mortalitesi yüksek olan pulmoner tromboendarterektomi ameliyatı ile ilgili tecrübelerimizin paylaşılması amaçlandı. Yöntemler: Şubat 2007 - Temmuz 2018 tarihleri arasında kliniğimizde akut pulmoner emboli ve kronik tromboembolik pulmoner hipertansiyon tanılarıyla ameliyat edilen toplam 13 hasta çalışmaya dâhil edildi. Bu hastaların 9’u acil 4’ü elektif olarak ameliyata alındı. Hastalara açık kalp ameliyatı şartlarında pulmoner tromboendarterektomi cerrahi prosedürü uygulandı. Hastaların geriye dönük bilgileri hastane yazılım sisteminden elde edildi. Bulgular: Pulmoner tromboendarterektomi uygulanan hastaların 6’sı bayan 7’si erkekti. Ortalama yaş 58 (38-71) olarak bulundu. Risk faktörü olarak 7 hastada derin ven trombozu, 3 hastada yakın zamanda geçirilmiş cerrahi, 2 hastada malinite, 5 hastada sigara kullanımı, 1 hastada behçet ve 1 hastada serebrovasküler olay öyküsü mevcuttu. Dört vaka, postoperatif 0-26 gün aralığında exitus oldu. Bunların 3’ü akut pulmoner emboli, 1’i kronik tromboembolik pulmoner hipertansiyon tanılı hastalardı. Sonuç ve Yorum: Pulmoner tromboendarterektomi uygulanan hastaların erken dönem pulmoner arter basınçlarında belirgin düşüş izlendi. Kronik tromboembolik pulmoner hipertansiyon tanısı konan hastalar, kalıcı arteriopati gelişmeden, pulmoner tromboendarterektomi ameliyatı için cerrahi merkezlere erken dönemde yönlendirilmelidir. Akut pulmoner emboli tanısı alan hastaların cerrahiye verilme zamanlamasının önemli olduğu kanaatindeyiz. Geciken ve hipotansif şok tablosunda ameliyata alınan hastaların mortalitesi yüksek olmaktadır.
Amac: Prematur bebeklerde sik gorulen, soldan saga sant ve mortalite ile morbiditenin onemli bir nedeni olan patent duktus arteriozusun, mekanik ventilatorde uzun sure takipli, bronkopulmoner displazi veya respiratuar distres sendromu gibi respiratuar problemleri olan veya medikal tedaviye ragmen patent duktus arteriozuslari kapanmayan hastalarda cerrahi ile erken donemde kapatilmasinin, dogum sonrasi donemde gelisebilecek komplikasyonlarin onlenmesi acisindan guvenilir bir yontem oldugunu literatur destekli sunmaktir. Gerecve Yontem: Necmettin Erbakan Universitesi Meram Tip Fakultesi Kalp Damar Cerrahisi bolumunde 2006-2015 yillari arasinda yapilan, prematur dogum oykusu olan ve ek kardiyak patolojisi olmayan 32 patent duktus arteriozus vakasi calismaya dahil edildi. Bulgular: Calismaya dahil edilen 32 hastanin 14’u (%43,7) kiz, 18 ‘i (%56,3) erkekti. Operasyon oncesi en sik gorulen rahatsizlik respiratuar distres sendromu idi (n=20). Hastalarin 22 tanesi(%68,7) pediatrik yogun bakimda entube takip edilmekteydi. Cerrahi prosedur; medikal tedavi ile duktuslari kapanmayan veya intrakranial kanama, bobrek yetmezligi veya trombositopeni gibi medikal tedavinin kontrendike oldugu vakalara uygulandi.Serimizde eksitus orani %15,6 idi (n=5). Mekanik ventilatorden ayrilma sureleri ortalama 6,2 gundu. Postoperatif ekokardiyografi kontrollerinde erken donemde yineleyen patent duktus arteriozus gorulmedi. Sonuc:Prematur bebeklerde patent duktus arteriozusa bagli dogum sonrasi gelisebilecek mortal ve morbid tablolari engellemek icin patent duktus arteriozus, medikal tedavinin basarisiz oldugu veya genel durumu kritik mekanik ventilator bagimli infantlardasanta bagli ikincil organ yetmezligi gelismeden once postnatal erken donemde guvenli bir sekilde kapatilabilir.
Backround: Peripheral arteriovenous malformations are rare clinical situations and the clinical spectrum varies from asymptomatic birth spot to life-threatining congestive heart failure. Also, venous compression and insufficiency result in stasis, dermatitis and ulcer development. Leg ulceration as a complication of arteriovenous malformation has been reported after tibial arteriovenous malformation causing venous congestion or femoral arteriovenous malformation resulting in a steal syndrome. Symptomatic and progressive growing arteriovenous malformations should be treated.Case Report: In this study we present a successful surgical and medical treatment of a fifty-four year old female patient with chronic leg ulcer due to newly diagnosed arteriovenous malformation.Conclusion: One of the important causes of chronic leg ulcer is delayed diagnoses like arteriovenous malformation so correct diagnoses and adequate treatment including surgery is important in patients with chronic leg ulcer due to arteriovenous malformation.
Amaç : Bu çalışmada diyabetik koroner arter hastalarında bypass ve stent uygulamalarında yaşın erken dönem yaşam kalitesi üzerine etkilerini karşılaştırmayı amaçladık. Gereç ve Yöntem: Çalışmaya Konya Üniversitesi Meram Tıp Fakültesi Kalp ve Damar Cerrahisi Merkezinde 01.07.2011-31.01.2012 tarihleri arasında opere olan ve Kardiyoloji kliniğinde perkütan transkatater koroner anjiyoplasti-stent yapılan diyabetik 85’şer hasta alındı. Preoperatif rutin biyokimyasal testler (AKŞ ve HbA1c) incelenerek diyabetik hastalar seçildi. Stent uygulanan ve opere olan hastalar 60>yaş ve 60≤yaş olarak 2 gruba ayrılarak Short Form-36 anketi uygulandı. Bulgular: Bypass ve stent uygulanan hastalar yaşa göre yaşam kalitesi alt boyutları karşılaştırıldığında fiziksel rol de anlamlı farklılık tespit edilirken(p<0,05), fiziksel işlev, ağrı,genel sağlık algısı, yaşamsallık, sosyal işlev, mental rol,ve mental sağlık arasında anlamlı fark bulunamamıştır (p>0,05). Sonuç: Diyabetik hastalarda yaşa göre erken dönem yaşam kalitesi incelendiğinde fiziksel rol de stent uygulamalarının daha etkili olduğu görülmektedir. Anahtar Kelimeler: SF-36, Diyabet, Koroner arter baypas cerrahisi, Perkütan Transkatater Koroner Anjiyoplasti
Objective:Our aim is to evaluate the closure of patent ductus arteriosus through surgery at an early stage, commonly seen in premature infants and a leading cause of left-to-right shunt and mortality/morbidity, as a safe modality to prevent complications that may develop in postnatal preiod in patients with bronchopulmonary displasia or respiratory distress syndrome followed up in mechanical ventilation, and whose ductus arteriosus can not be closed despite medical treatment.Material and Methods:Thirty two cases of patent ductus arteriosus with premature birth history and no additional cardiac pathology, performed in the Department of Cardiovascular Medical School, Necmettin Erbakan University between 2006-2015 were included into the study.Results:Of the 32 patients, 14 (43,7%) were females and 18 (56,3%) were males. The most frequently seen preoperative disorder was respiratory distress syndrome(n=20). Twenty-two (68%) of the patients were following as intubated in newborn intensive care unit. Surgical procedure was performed in patients whose ductus were not closed via medical treatmentorin whom medical treatment was contraindicated for problems such as intracranial hemorrhage, renal failure or thrombocytopenia. Excitus rate was 15,6% (n=5) in our series. Removal time of mechanical ventilation was average 6,2 days. Postoperative echocardiography showed no recurrence of patent ductus arteriosus.Conclusion:Prevention of postnatal mortality and morbidity due to patent ductus arteriosus in premature infants can be achieved by early surgical closure during postnatal early period before secondary organ failure due to shunting develops and infants with critical general status-dependent on mechanical vantilation-,and for whom medical treatment is unsuccessful.
Infective endocarditis characterized by microbial infection of the endothelial surface of the heart,has an estimated annual incidence of 3 to 9 cases per 100.000 persons in industralized countries. Although common species causing infective endocarditis include streptococci, staphylococci, enterococci and fastidious gram negative coccobacilli, aortic valve replacement due to lactococcus lactis infective endocarditis seen in the literature, even if rarely. In this study we presented a 34 year old male patient underwent surgery, diagnosed with lactococcus lactis infective endocarditis.
Klinigimize Aort Darligi (AD) tanisiyla kabul edilen iki hastamiza, ileri yas ve klasik cerrahi riskinin yuksek olmasi nedeniyle anterior torakotomi ile minimal invaziv girisim yapilarak dikissiz aort kapagi implantasyonu yapilmistir. Minimal invaziv girisimin ileri yas ve yuksek riskli ciddi aort darligi olan hastalarda, klasik cerrahiye oranla cok daha uygun bir cerrahi tedavi secenegi oldugu kanisindayiz.
A 72-year-old female patient with respiratory distress and chest pain was referred for echocardiography after which a severe aortic stenosis was diagnosed. From clinical perspective an AVR would have carried too much risk in this case, therefore TAVI with transapical approach via left anterior thoracotomy was the treatment of choice. In this case report, we describe our experience with this new procedure in our country.
Two patients accepted to our clinic with the diagnosis of aortic stenosis were considered to have high risk for classic surgery and were planned to undergo aortic valve replacement by a minimally invasive procedure with anterior thoracotomy. We believe that, the minimally invasive procedure is much more convenient than classical surgical techniques in patients having high risk for severe aortic stenosis.
Amaç: Bu çalışmada koroner arter baypas greftleme (KABG) yapılan diyabet hastalarında renal doz dopamin infüzyonunun profilaktik kullanımının klinik sonuçları değerlendirildi. Çalışmaplanı:Bu prospektif randomize çalışmada elektif KABG yapılması planlanan 40 ardışık diyabet hastası iki eşit gruba randomize edildi: grup 1’e anestezi indüksiyonundan itibaren 48 saat süreyle renal dozda (2.5-4.0 mg/kg/dk.) dopamin infüzyonu verildi; grup 2 ise tedavi edilmemiş kontrollerden oluşuyordu. Kardiyopulmoner baypas için aortik ve sağ atriyal kanülasyonu ile standart sternotomi tekniği uygulandı. Bul gu lar: Günlük idrar çıkışı, sıvı dengesi, serum kreatinin, kan üre düzeyleri ve kreatinin klirensi üç ve beşinci günlerde ölçüldü. Kontrol grubunda ameliyat sonrası üçüncü ve beşinci günlerde kreatinin klirens düzeyleri sırasıyla 24.8±12.3 mL/dk ve 18.1±10.1 mL/dk azaldı. Dopamin grubunda ameliyat sonrası üçüncü ve beşinci günlerde kreatinin klirens düzeyleri sırasıyla, 7.7±10.8 mL/dk. (p=0.005) ve 10.7±11.7 mL/dk. (p=0.001) arttı. Kontrol grubuna kıyasla, grup 1’deki hastaların serum kreatinin düzeyinde üçüncü ve beşinci günlerde daha az artış görüldü (p<0.001). Sonuç:Renal tübüler fonksiyonun göstergesi olan kreatinin ve kreatinin klirens düzeyleri, anestezi indüksiyonun başladığı zaman renal doz dopamin infüzyonu ile pozitif etkilendi. Verilerimiz, özellikle diyabet hastalarında ameliyat sonrası renal fonksiyonların yeniden normalleşmesine katkıda bulunabilir. Anah tar söz cük ler: Koroner arter baypas greftleme; diabetes mellitus; renal doz dopamin; renal fonksiyon bozukluğu. Background:This study aims to evaluate clinical results of the prophylactic use of renal dose dopamine infusion in diabetic patients undergoing coronary artery bypass grafting (CABG). Methods: In this prospective randomized study, 40 consecutive diabetic patients who were scheduled for elective CABG were randomized into two equal groups: group 1 received dopamine infusion at renal dose (2.5-4.0 mg/kg/min) starting from induction of anesthesia for 48 hours; group 2 consisted of untreated controls. Standard sternotomy technique using aortic and right atrial cannulation was performed for cardiopulmonary bypass. Results:Daily urine output, fluid balance, serum creatinine, blood urea levels and creatinine clearance were measured at three and five days. In the control group, third and fifth postoperative day, creatinine clearance levels decreased about 24.8±12.3 mL/min and 18.1±10.1 mL/min, respectively. In the dopamine group, creatinine clearance levels in the third and fifth postoperative days increased by 7.7±10.8 mL/min (p=0.005) and 10.7±11.7 mL/min (p=0.001), respectively. Group 1 patients demonstrated less increase in serum creatinine level at three and five days than the controls (p<0.001). Conclusion: Creatinine and creatinine clearance levels, suggestive of renal tubular function, were positively affected by renal dose dopamine infusion started at time of anesthesia induction. Our data may help us to re-normalize the renal functions in the postoperative period in diabetic patients, particularly.
Background: This study aims to evaluate clinical results of the prophylactic use of renal dose dopamine infusion in diabetic patients undergoing coronary artery bypass grafting (CABG).Methods: In this prospective randomized study, 40 consecutive diabetic patients who were scheduled for elective CABG were randomized into two equal groups: group 1 received dopamine infusion at renal dose (2.5-4.0 mg/kg/min) starting from induction of anesthesia for 48 hours; group 2 consisted of untreated controls. Standard sternotomy technique using aortic and right atrial cannulation Was performed for cardiopulmonary bypass.Results: Daily urine output, fluid balance, serum creatinine, blood urea levels and creatinine clearance were measured at three and five days. In the control group, third and fifth postoperative day, creatinine clearance levels decreased about 24.8 +/- 12.3 mL/min and 18.1 +/- 10.1 mL/min, respectively. In the dopamine group, creatinine clearance levels in the third and fifth postoperativie days increased by 7.7 +/- 10. 8 mL/min (p=0.005) and 10.7 +/- 11.7 mL/min (p=0.001), respectively. Group 1 patients demonstrated less increase in serum creatinine level at three and five days than the controls (p<0.001).Conclusion: Creatinine and creatinine clearance levels, suggestive of renal tubular function, were positively affected by renal dose dopamine infusion started at time of anesthesia