The involvement of enthesis like disc space is the typical lesion of spondylarthropathies. Out of 240 patients with spondylarthropathies, 10 (7 M, 3 W; mean age: 37 years) have spondylodiscitis, affecting a total of 13 disc spaces: 1 cervical, 2 thoracic, 10 lumbar. The mean duration of spondylarthropathy at the time of diagnosis of spondylodiscitis is 10 years. Spondylodiscitis has a variable clinical presentation: painful (6 cases), asymptomatic (4 cases). Its coexistence with typical radiographic signs of spondylarthropathy added to the exclusion of bacterial origin, permit to link it to spondylarthropathy. Its evolution is generally favourable.
Les auteurs rapportent les observations de 2 femmes, âgees respectivement de 32 et 45 ans, suivies pour un LED (Lupus Erythemateux Dissemine) complique en cours d'evolution d'une neuropathie peripherique sensitivo-motrice de type axonale, resistante aux corticoides a fortes doses justifiant le recours au cyclophosphamide avec une reponse favorable.
Sacroiliitis during the course of sarcoidosis is an uncommon event usually due to tuberculosis. Sacroiliitis due to sarcoidosis itself is exceedingly rare. A case is reported in a 73-year-old woman who developed acute destructive bilateral sacroiliitis as the first manifestation of diffuse sarcoidosis involving the lungs, liver, spleen, and bone. Serum calcium was elevated. Computed tomography of the sacroiliac joints showed subchondral erosions and joint space loss most marked on the right. A sacroiliac joint biopsy confirmed that the cause was sarcoidosis.
A 35-year-old female developed primary biliary cirrhosis, polymyositis, and systemic scleroderma. The diagnosis of primary biliary cirrhosis was suggested by the fortuitous identification of antimitochondrial antibodies and was confirmed by the liver biopsy.