AbstractThe structures of the products from the nitration of 2‐ and 4‐oxodihydroquinolines were assigned based on Nuclear Overhauser Effects of their nmr spectra and confirmed by unambiguous synthesis.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAdditions and Corrections - Structure of NogalamycinPaul Wiley, Ronald Kelly, E. Caron, Veronica Wiley, Jian Johnson, Forrest MacKellar, and Stephen MizakCite this: J. Am. Chem. Soc. 1979, 101, 2, 512Publication Date (Print):January 1, 1979Publication History Published online18 February 2004Published inissue 1 January 1979https://pubs.acs.org/doi/10.1021/ja00496a600https://doi.org/10.1021/ja00496a600research-articleACS PublicationsRequest reuse permissionsArticle Views19Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
AbstractDie Strukturen von Steffimycin (Ia) und Steffimycin B (Ib) werden bestimmt.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructures of steffimycin and steffimycin BRobert C. Kelly, Ilse Schletter, James M. Koert, Forrest A. MacKellar, and Paul F. WileyCite this: J. Org. Chem. 1977, 42, 22, 3591–3596Publication Date (Print):October 1, 1977Publication History Published online1 May 2002Published inissue 1 October 1977https://doi.org/10.1021/jo00442a032RIGHTS & PERMISSIONSArticle Views242Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (838 KB) Get e-Alertsclose Get e-Alerts
Chemischer InformationsdienstVolume 8, Issue 16 Physical Organic Chemistry ChemInform Abstract: STRUCTURE OF NOGALAMYCIN P. F. WILEY, P. F. WILEYSearch for more papers by this authorR. B. KELLY, R. B. KELLYSearch for more papers by this authorE. L. CARON, E. L. CARONSearch for more papers by this authorV. H. WILEY, V. H. WILEYSearch for more papers by this authorJ. H. JOHNSON, J. H. JOHNSONSearch for more papers by this authorF. A. MACKELLAR, F. A. MACKELLARSearch for more papers by this authorS. A. MIZSAK, S. A. MIZSAKSearch for more papers by this author P. F. WILEY, P. F. WILEYSearch for more papers by this authorR. B. KELLY, R. B. KELLYSearch for more papers by this authorE. L. CARON, E. L. CARONSearch for more papers by this authorV. H. WILEY, V. H. WILEYSearch for more papers by this authorJ. H. JOHNSON, J. H. JOHNSONSearch for more papers by this authorF. A. MACKELLAR, F. A. MACKELLARSearch for more papers by this authorS. A. MIZSAK, S. A. MIZSAKSearch for more papers by this author First published: April 19, 1977 https://doi.org/10.1002/chin.197716049AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References P. F. WILEY, R. B. KELLY, E. L. CARON, V. H. WILEY, J. H. JOHNSON, F. A. MACKELLAR, S. A. MIZSAK, STRUCTURE OF NOGALAMYCIN, J. Am. Chem. Soc., 1977, 99, 542. DOI: 10.1021/ja00444a038; 10.1021/ja00444a038 CASPubMedWeb of Science®Google Scholar Volume8, Issue16April 19, 1977 ReferencesRelatedInformation
Die Struktur des Antibioticums Sparsomycin wurde zu (I) ermittelt.
A homologous series of straight-chain lincomycin 2-monoesters, comprised of both acyl and carbonate esters, was synthesized. Good antibacterial activity was observed with esters of chain lengths from C4 to C16. Esters with chain lengths from C12 to C16 are tasteless and highly active in vivo in mice infected with Staphylococcus aureus. The carbonate esters show essentially the same taste and bioactivity as the acyl esters. The long-chain lincomycin 2-esters appear to have the desired properties required for formulation as a tasteless pediatric preparation.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTirandamycin. I. Structure assignmentKenneth L. Rinehart Jr., Forrest A. MacKellar, Marvin F. Grostic, Edward C. Olson, Richard J. Wnuk, and Alan R. BranfmanCite this: J. Am. Chem. Soc. 1971, 93, 19, 4943–4945Publication Date (Print):September 1, 1971Publication History Published online1 May 2002Published inissue 1 September 1971https://pubs.acs.org/doi/10.1021/ja00748a067https://doi.org/10.1021/ja00748a067research-articleACS PublicationsRequest reuse permissionsArticle Views154Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Chemischer Informationsdienst. Organische ChemieVolume 2, Issue 51 Heterocyclic Compounds ChemInform Abstract: SYNTH. UND STRUKTURBEWEIS FUER EIN NEUES 1,4-BENZODIAZEPIN J. SZMUSZKOVICZ, J. SZMUSZKOVICZSearch for more papers by this authorC. C. CHIDESTER, C. C. CHIDESTERSearch for more papers by this authorD. J. DUCHAMP, D. J. DUCHAMPSearch for more papers by this authorF. A. MACKELLAR, F. A. MACKELLARSearch for more papers by this authorG. SLOMP, G. SLOMPSearch for more papers by this author J. SZMUSZKOVICZ, J. SZMUSZKOVICZSearch for more papers by this authorC. C. CHIDESTER, C. C. CHIDESTERSearch for more papers by this authorD. J. DUCHAMP, D. J. DUCHAMPSearch for more papers by this authorF. A. MACKELLAR, F. A. MACKELLARSearch for more papers by this authorG. SLOMP, G. SLOMPSearch for more papers by this author First published: December 21, 1971 https://doi.org/10.1002/chin.197151366Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume2, Issue51December 21, 1971 RelatedInformation
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1-Dodecylpyridinium dodecyl sulfateGunther S Fonken and Forrest A. MacKellarCite this: J. Med. Chem. 1970, 13, 6, 1246Publication Date (Print):November 1, 1970Publication History Published online1 May 2002Published inissue 1 November 1970https://pubs.acs.org/doi/10.1021/jm00300a062https://doi.org/10.1021/jm00300a062research-articleACS PublicationsRequest reuse permissionsArticle Views23Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Structure of SparsomycinPaul F. Wiley and Forrest A. MacKellarCite this: J. Am. Chem. Soc. 1970, 92, 2, 417–418Publication Date (Print):January 1, 1970Publication History Published online11 December 2002Published inissue 1 January 1970https://doi.org/10.1021/ja00705a623RIGHTS & PERMISSIONSArticle Views98Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (277 KB) Get e-Alerts Get e-Alerts
Abstract3,4‐O‐Anisyliden‐lincomycin (I) und Tritylchlorid (II) reagieren in Aceton in Gegenwart von Triäthylamin zum 7‐O‐Trityl‐Derivat (IIIa) (72% Ausbeute), das mit Benzoylchlorid in einem Pyridin‐Chloroform‐Gemisch zu (IIIb) verestert wird.
Chemischer Informationsdienst. Organische ChemieVolume 1, Issue 11 Heterocyclic Compounds ChemInform Abstract: SYNTH. UND BIOAKTIVITAET VON LINCOMYCIN-7-MONOESTERN A. A. SINKULA, A. A. SINKULASearch for more papers by this authorW. MOROZOWICH, W. MOROZOWICHSearch for more papers by this authorC. LEWIS, C. LEWISSearch for more papers by this authorF. A. MACKELLAR, F. A. MACKELLARSearch for more papers by this author A. A. SINKULA, A. A. SINKULASearch for more papers by this authorW. MOROZOWICH, W. MOROZOWICHSearch for more papers by this authorC. LEWIS, C. LEWISSearch for more papers by this authorF. A. MACKELLAR, F. A. MACKELLARSearch for more papers by this author First published: March 17, 1970 https://doi.org/10.1002/chin.197011383Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume1, Issue11March 17, 1970 RelatedInformation
Tritylation of 3,4-O-anisylidene lincomycin (II) was found to give 7-O-trityl-3,4-O-anisplidene lincomycin (III), a key intermediate in the synthesis of lincomycin-2-monoesters. The structure of III was established by NMR. Phosphorylation of III with POCls in pyridine gave the resulting dichlorophosphate IV which after hydrolysis and treatment with 80% aqueous acetic acid (100°, 30 min.) gave lincomycin-2-phosphate (V). The water-soluble ester V is inactive in the plate antibacterial assay using S. lutea, although in uiuo V is as active as the parent compound lincomycin (I) in mice infected with S. aureus. V gave slightly higher blood levels than the parent compound I upon oral administration in dogs. The taste of V is less bitter than I.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAdditions and Corrections - Addition of Alkyl Vinyl Ethers to Δ16-20-Keto Steroids. I.J. Pike, M. Rebenstorf, G. Slomp, and F. MacKellarCite this: J. Org. Chem. 1964, 29, 12, 3743Publication Date (Print):December 1, 1964Publication History Published online14 November 2002Published inissue 1 December 1964https://pubs.acs.org/doi/10.1021/jo01035a625https://doi.org/10.1021/jo01035a625research-articleACS PublicationsRequest reuse permissionsArticle Views15Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSTRUCTURE STUDIES BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY. I. THE PHOTODIMER OF N-METHYL-2-PYRIDONEG. Slomp, F. A. MacKellar, and L. A. PaquetteCite this: J. Am. Chem. Soc. 1961, 83, 21, 4472–4473Publication Date (Print):November 1, 1961Publication History Published online1 May 2002Published inissue 1 November 1961https://pubs.acs.org/doi/10.1021/ja01482a043https://doi.org/10.1021/ja01482a043research-articleACS PublicationsRequest reuse permissionsArticle Views111Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts