Asthma from intolerance of sulphites has been the subject of clinical work by our team since 1984. In 1986, we advised that asthma from sulphite intolerance was more frequent in patients who presented with illness from aspirin or the Fernand Widal syndrome. So it has emerged that there are clear therapeutic problems since sulphites as preservatives are present in other forms in some anti-allergy drugs, anti-histamines used for ORL.

In assessing the importance of the "allergen eviction" factor in the treatment of infantile allergies, the authors begin an inventory of those elements in the environment that concern perennial rhinitis. From 200 observations of allergic children (all mixed diagnoses) they found 21 observations of rhinitis alone, predominantly boys. The environments of two groups (all allergics--rhinitis alone) were compared. No difference for: Home, country, town heating allergens found. Found significant differences for the type of house new-old those elements of domestic comfort (carpets, feather beds, aeration, soft toys) agreement between the results of tests and the environment domestic animals or permanent proximity. Found fundamental differences for psychological environmental factors (absent in rhinitis). It seems that perennial rhinitis probably arises from abundance of domestic antigens more than for the other allergic manifestations, as the nose is the first filter to receive foreign particles.

This work is in the purview of epidemiological studies that concern the environment of asthmatic children. Infantile asthma is found especially in children who live in the country, in an electrically-heated house and who sleep in a badly orientated room. The environment is composed of feather-bedding, soft-toy animals and animals from the countryside. The role of tobacco and insufficient aeration has been shown in this enquiry. School attendance is not disturbed by development of asthma. The majority of teachers do not understand infantile asthma. This study is to emphasize the importance of the environment in the development of allergic infantile asthma and the possibilities of its prevention. Information to the teachers, as well as the treating physicians, is also necessary for prevention.

The aim of this study was to present briefly the different techniques for measurement of nasal resistance and to show the importance that we attribute to this measurement. Within the framework of the allergological investigation rhinamometry is a parameter that allows evaluation of the results of allergenic nasal provocation. Nasal provocation is in the framework as a complementary examination that is often indespensable to confirm with most possible certainty the involvement of an allergen in the ORL pathology. Positive etiological diagnosis is a fundamental basis for therapeutic advice.

At the end of this quick survey of asthma in children we can only emphasize: The less than diagnostic characteristics of this syndrome, often ignored and so not considered. This explain perhaps, in part the current increase in frequency. The often precocious characteristics of the first manifestations right in the middle of the development of the respiratory tree. Of the need to make a team by associating the parents, the family physician and the allergy specialist, a team to which the child should be added as soon as possible. Of the multiplicity of factors that cause asthma, which embrace syndromes that are very personal to each patient and require special consideration for each, without stereotype or a chain.

A case of asthma in an infant child from a family already showed inability to tolerate cow milk and which only responded when such food was discontinued. The study concerns: a. The diagnostic methods of the disease; b. The relationship between the IPLV and hypotrophy that was perceptible in the infant child, a hypotrophy that was revealed in the course of the evolution of the disease. Finally, a study of the documents on the pathogenic processes enabled us to locate the observation involved to half-way between IgE dependent cases and those other cases that produce delayed hypersensitivity.

A school environmental study of about 20,000 children from the French department of MAINE and LOIRE (1/100 of French territory and 1/100 of the total population) was made during the summer of 1987 in all the schools of the region. The replies allowed evaluation of: -- The elements of the environment; . urban or rural . type of building . soils . domestic animals (types, lifestyle, large or small, relationship with the children). -- The proportion of allergic children per classroom, types of sickness, suggestions made by parents, eventual allergic accidents during class hours. In addition, school teachers were asked to comment on the subject. Their answers showed extreme variety of attitude towards allergy, there were those who refuted it, some fully accepted and others who asked for more information so that they could be more help to their students. A prime interest of the study lies in the dialogue between parents, teachers and physicians as the children spent most of the daytime at school and therefore the quality of the environment is a major factor in infantile allergy.

The typing of common Phleol Pollen and wheat Antigen has been realized with these Antigens Fractions from PASTEUR Institute using FPLC PHARMACIA Chromatograph. The discover of commun Antigen has been obtained with RAST Inhibition technic. It exist common Antigen fractions between phleol and wheat, but no between wheat an phleol. The results are in favor of less allergic quality of wheat.

Influence de l'adenoamygdalectomie sur les affections allergiques. Indications de l'adenoamygdalectomies dans les allergies ORL