ChemInformVolume 19, Issue 11 Physical Organic Chemistry ChemInform Abstract: Crystal Structure of the 10-13 Sequence of Angiotensinogen L-Leucyl-L-leucyl-L-valyl-L-tyrosyl Methyl Ester G. PRECIGOUX, G. PRECIGOUX Lab. Cristallogr., Univ. Bordeaux I, 33405 Talence, Fr.Search for more papers by this authorC. COURSEILLE, C. COURSEILLE Lab. Cristallogr., Univ. Bordeaux I, 33405 Talence, Fr.Search for more papers by this authorS. GEOFFRE, S. GEOFFRE Lab. Cristallogr., Univ. Bordeaux I, 33405 Talence, Fr.Search for more papers by this authorF. LEROY, F. LEROY Lab. Cristallogr., Univ. Bordeaux I, 33405 Talence, Fr.Search for more papers by this author G. PRECIGOUX, G. PRECIGOUX Lab. Cristallogr., Univ. Bordeaux I, 33405 Talence, Fr.Search for more papers by this authorC. COURSEILLE, C. COURSEILLE Lab. Cristallogr., Univ. Bordeaux I, 33405 Talence, Fr.Search for more papers by this authorS. GEOFFRE, S. GEOFFRE Lab. Cristallogr., Univ. Bordeaux I, 33405 Talence, Fr.Search for more papers by this authorF. LEROY, F. LEROY Lab. Cristallogr., Univ. Bordeaux I, 33405 Talence, Fr.Search for more papers by this author First published: March 15, 1988 https://doi.org/10.1002/chin.198811080Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume19, Issue11March 15, 1988 RelatedInformation
C20H29N2Os.C4H304, Mr=492.5 , mono- clinic, P21, a=11.224(4), b=6.645(2), c-- 17.824 (5)A, fl= 105.52 (3) ° , V= 1280.9 (7)A 3, Z =2, D x=1.27gcm -3, MoKa, 2=0.71069/~, g= 1.06 cm -1, F(000) = 524, T = 293 K, final R = 0.089 for 1187 observed reflections. The title compound (MK-421) is a potent orally active inhibitor of angiotensin-converting enzyme. The molecule is obser- ved with Ala NH + as a positively charged group. The backbone shows an extended conformation at Ala. The crystal-structure conformation is compared with the proposed biologically active conformation of enalapril