Combination of cabozantinib with PF-562271 delays tumor recurrence after treatments cessation.
Supplementary Figure 4 from Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
Supplementary Figure Legends 1-6, Tables 1-2 from Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
PDF file - 48K, RPPA data for the colon and melanoma cell lines. Values are log-base 2, normalized to both total protein loading per sample and the median protein expression. HT29/WiDr, and Colo201/Colo205 are derived from the same patient under different time courses/conditions, and therefore may be provide limited additional data (Semple TU et al., Cancer Res. 1978 May;38(5):1345-55, Chen TR et al Cancer Genet Cytogenet. 1987 Jul;27(1):125-34). Sensitivity analysis demonstrates no change in the conclusions with the inclusion or exclusion of these isogenic cell lines.
PDF file 190K, Figure S6. (A, B) Glu-tubulin immunofluorescence staining (green) in RMUG-S and RMUG-L cells treated with 100 nM KX-01 for 24 hours and incubated with anti-glu-tubulin antibody followed by Alexa Fluor 488-conjugated anti-rabbit antibody. Nuclei (blue) were stained with DAPI. Left: tubulin stain only; Middle: DAPI nuclear stain; Right: tubulin and DAPI nuclear stain
Supplementary Table S1 from Src Continues Aging: Current and Future Clinical Directions
Supplementary Figure 3 from Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
PDF file - 636K, Representative images of ALDH1 staining and enumeration by Aperio Genie with color.
Supplementary Table 1 from BMP4 Promotes Prostate Tumor Growth in Bone through Osteogenesis
PDF file 196K, Figure S2. Effects of KX-01 and oxaliplatin on cell proliferation (Ki-67; A), angiogenesis (CD31; B), apoptosis (Cleaved caspase-3; C) RMUG-L model. Original magnification 200x . Bars in the graphs correspond sequentially to the labeled columns of images on the left. Data are shown as mean {plus-minus} standard deviation (error bars). *p<0.05, **p<0.01 compared with the control group