A series of patients operated upon for occlusive and aneurysmal disease with replacement by a Teflon prosthetic graft is presented.

In the past year at St. Vincent's Hospital open cardiac surgery has been performed two to three times a week on experimental animals. It required five months of constantly careful work before the first animal survived. Only after considerable time was the technic perfected so that the non-survivor became the exception. Thereafter an occasional run of failures would occur. The amount of work and teamwork required for such results is to be emphasized. While the dog is a difficult animal to keep alive after open heart surgery as described, success must be achieved on such animals before operations on human beings are attempted.

There are several different types and causes of lymphedema. When both the skin and the subcutaneous tissues are involved, the part becomes exceedingly large and surgery may be necessary for the patient's comfort and safety.

1.1. A new technic for producing experimental arterial embolism in dogs is described.2.2. The effect of the blood stream force on fresh and old clots is noted.3.3. The results of the intra-arterial administration of trypsin upon the experimentally produced emboli are reported. No lysis of clots was obtained in any of these experiments.4.4. If there is a fibrinolytic effect of trypsin on blood clots, it is not present in old clots in the aorta.

purpose of this paper is to point out the segmental char-acteristic of the great majority of the peripheral occlusive garterial diseases and the importance of angiographic studies in the evaluation of these pathological conditions. been brought up in the past by various and we emphasize it because of the high incidence of segmental occlusions in our series of cases.

We wish to emphasize, the following: 1.1. The surgical treatment of arterial aneurysm must be individualized. Of the operations, the anastomosing or obliteration procedures potentially are the best. Obliteration of the aortic aneurysm is possible if certain technical difficulties are overcome.2.2. Some arteriovenous aneurysms can be excised and anastomosed or the arterial defect sutured. In others quadrilateral ligation is not sufficient, but multiple resection of all the vessels involved in the process must be performed.3.3. Congenital arteriovenous aneurysms may be quiescent for years, then become active and, like cancer, prove very difficult to eradicate. Neologically, arterionia is suggested.4.4. A syndrome not emphasized before is presented. In this syndrome arteriovenous connections are misdiagnosed as varicose veins. This occurs in our practice in 25 per cent of those sent for advanced vein pathology. The syndrome of arterial varices can be diagnosed by attention to the features which have been pointed out. This syndrome should be suspected particularly if the veins are on the posterolateral or lateral aspect of the leg, if the patient is young, if there is increased local heart, and if the veins recur after adequate vein resection.

1.1. This syndrome, to our knowledge, has not been emphasized before.2.2. These arterial venous connections are usually misdiagnosed as varicose veins. These connections occur much more commonly than is supposed. In our practice 24 per cent of the patients we see with advanced varicosities have this syndrome. The syndrome can be diagnosed by the various features already discussed.3.3. Accurate diagnosis of this syndrome is required in order to perform the necessary surgical treatment. This is also important from the prognostic standpoint.4.4. The condition should be suspected if the veins appear rapidly on the lateral or posterior portions of the legs, if the patient is relatively young, if there is increased local heat and if the veins recur after previous competent vein surgery.5.5. Adequate and at times repeated surgery will control the condition.6.6. The tendency of these arterial varices to recur seems inherent. With the immaturity of the blood vessels and their local spread and difficulty of eradication, the condition simulates new growth.

1.1. Observations in arterial and arteriovenous aneurysms are presented. 2.2. A synopsis of five patients on whom operations were performed at sea on a U.S.N. Hospital Ship is given. 3.3. Surgical operations are discussed. 4.4. After-care is specified.

The exceedingly high incidence of vascular diseases among those living to the age of 40 has made the study of therapeutic methods to care for these vascular lesions of interest to all. A thorough survey recently completed of 537 employees of a large department store who had worked for fifteen years or more, and all of whom were over 40, showed the surprising x-ray evidence of arteriosclerosis of 46 per cent. In this group only 12 per cent had subnormal oscillometric readings; therefore the arteriosclerosis was subclinical and unless x-ray films had been taken the person would not have been aware of the condition. Men and women differed both in incidence and in degree of arterial changes. While there was x-ray calcification in 44 per cent of the men, only 18 per cent of the women showed roentgenographic changes. In the group with advanced changes (plaques and the like) there