W em easured twom om entsofthelepton m om entum spectrum in B ! X ‘ ,where‘= eor ,for p‘ 1:5 G eV=c. From these we derive the Heavy Q uark Expansion (HQ E)param eters (M S)= 0:39 0:03jstat 0:06jsys 0:12jth G eV and 1 = 0:25 0:02jstat 0:05jsys 0:14jth G eV ,through order 1=M 3 B in the non-perturbative expansion and 0 2 s in the perturbative expansion. The theoreticalexpression needed to extract jVcbjfrom the m easured sem ileptonic width is evaluated using theseHQ E param eters.Com bined with theworld averageofthesem ileptonicwidth,we nd jVcbj= (40:8 0:5j sl 0:4j( 1; )exp 0:9jth) 10 .Finally,theshortrange b-quark m assm 1S b is evaluated and found to be4:82 0:07jexp 0:11jth G eV/c . Subm itted to the 31 InternationalConferenceon High Energy Physics,July 2002,Am sterdam

BACKGROUND:Obesity negatively impacts asthma control, but the inflammatory mechanisms are poorly understood.OBJECTIVE:To explore which systemic inflammatory mediators mediate the effects of obesity on asthma control.METHODS:The subjects with stable asthma (n = 108) underwent assessment of clinical characteristics, which included using The Asthma Control Questionnaire (ACQ)-6. Obesity was defined as a body mass index (BMI) of ≥30 kg/m2, overweight was defined as BMI between 25 to 29.9 kg/m2, and lean weight was defined as BMI < 25 kg/m2. Body composition, including fat mass (FM), visceral fat area (VFA), and percentage body fat (PBF) was analyzed by bioimpedance. Serum interleukin (IL) 4, IL-5, IL-8, IL-13, IL-17, chemokine (C-C motif) ligand (CCL) 17, CCL22, leptin, adiponectin, C-reactive protein (CRP), and interferon (IFN) gamma were measured by using ELISA. Linear regression models were fitted according to the Baron and Kenny procedures for mediation analysis.RESULTS:FM (12.73 ± 3.95 versus 18.59 ± 2.95 versus 27.82 ± 5.17 kg; p < 0.0001), VFA (65.99 ± 23.17 versus 93.96 ± 10.28 versus 123.10 ± 18.34 cm2; p < 0.0001), PBF (23.86 ± 7.46 versus 30.74 ± 5.08 versus 36.21 ± 6.28 %; p = 0.0003) and ACQ-6 values (0.83 [0, 1.17]) versus 1.15 [0.50, 1.75] versus 1.33 [0.83, 1.83] score; p = 0.002) were different among lean (n = 52), overweight (n = 37), and obese (n = 19) subjects. Serum levels of leptin, IL-5, IL-13, IL-17, CCL17, CRP, and IFN-gamma in the obese group were significantly elevated compared with the subjects who were lean or overweight (all p < 0.05). The mediation analyses found that the effect of obesity, assessed by BMI, on ACQ-6 was significantly mediated through IL-13 and CCL17. Furthermore, IL-13 and CCL17 mediated the effects of body composition (FM, VFA and PBF) on ACQ-6. The effects of obesity assessed by body composition, but not by using BMI, on ACQ-6 were mediated by leptin.CONCLUSION:Our mediation analysis confirmed that systemic inflammation biomarkers, such as leptin, CCL17, IL-4, and IL-13, mediated the effects of obesity on asthma control. This warrants prospective exploration in this distinct asthma phenotype in the future.

Z. Li, A. Lopez, H. Mendez, J. Ramirez, G. S. Huang, D. H. Miller, V. Pavlunin, B. Sanghi, E. I. Shibata, I. P. J. Shipsey, G. S. Adams, M. Chasse, M. Cravey, J. P. Cummings, I. Danko, J. Napolitano, Q. He, H. Muramatsu, C. S. Park, W. Park, E. H. Thorndike, T. E. Coan, Y. S. Gao, F. Liu, M. Artuso, C. Boulahouache, S. Blusk, J. Butt, E. Dambasuren, O. Dorjkhaidav, J. Li, N. Menaa, R. Mountain, R. Nandakumar, R. Redjimi, R. Sia, T. Skwarnicki, S. Stone, J. C. Wang, K. Zhang, S. E. Csorna, G. Bonvicini, D. Cinabro, M. Dubrovin, R. A. Briere, G. P. Chen, J. Chen, T. Ferguson, G. Tatishvili, H. Vogel, M. E. Watkins, J. L. Rosner, N. E. Adam, J. P. Alexander, K. Berkelman, D. G. Cassel, V. Crede, J. E. Duboscq, K. M. Ecklund, R. Ehrlich, L. Fields, R. S. Galik, L. Gibbons, B. Gittelman, R. Gray, S. W. Gray, D. L. Hartill, B. K. Heltsley, D. Hertz, L. Hsu, C. D. Jones, J. Kandaswamy, D. L. Kreinick, V. E. Kuznetsov, H. Mahlke-Kruger, T. O. Meyer, P. U. E. Onyisi, J. R. Patterson, D. Peterson, E. A. Phillips, J. Pivarski, D. Riley, A. Ryd, A. J. Sadoff, H. Schwarthoff, M. R. Shepherd, S. Stroiney, W. M. Sun, D. Urner, T. Wilksen, M. Weinberger, S. B. Athar, P. Avery, L. Breva-Newell, R. Patel, V. Potlia, H. Stoeck, J. Yelton, P. Rubin, C. Cawlfield, B. I. Eisenstein, G. D. Gollin, I. Karliner, D. Kim, N. Lowrey, P. Naik, C. Sedlack, M. Selen, J. Williams, J. Wiss, K. W. Edwards, D. Besson, T. K. Pedlar, D. Cronin-Hennessy, K. Y. Gao, D. T. Gong, Y. Kubota, T. Klein, B. W. Lang, S. Z. Li, R. Poling, A. W. Scott, A. Smith, S. Dobbs, Z. Metreveli, K. K. Seth, A. Tomaradze, P. Zweber, J. Ernst, A. H. Mahmood, H. Severini, D. M. Asner, S. A. Dytman, W. Love, S. Mehrabyan, J. A. Mueller, and V. Savinov

J. L. Rosner, N. E. Adam, J. P. Alexander, K. Berkelman, D. G. Cassel, V. Crede, J. E. Duboscq, K. M. Ecklund, R. Ehrlich, L. Fields, R. S. Galik, L. Gibbons, B. Gittelman, R. Gray, S. W. Gray, D. L. Hartill, B. K. Heltsley, D. Hertz, C. D. Jones, J. Kandaswamy, D. L. Kreinick, V. E. Kuznetsov, H. Mahlke-Kruger, T. O. Meyer, P. U. E. Onyisi, J. R. Patterson, D. Peterson, E. A. Phillips, J. Pivarski, D. Riley, A. Ryd, A. J. Sadoff, H. Schwarthoff, X. Shi, M. R. Shepherd, S. Stroiney, W. M. Sun, D. Urner, T. Wilksen, K. M. Weaver, M. Weinberger, S. B. Athar, P. Avery, L. Breva-Newell, R. Patel, V. Potlia, H. Stoeck, J. Yelton, P. Rubin, C. Cawlfield, B. I. Eisenstein, G. D. Gollin, I. Karliner, D. Kim, N. Lowrey, P. Naik, C. Sedlack, M. Selen, E. J. White, J. Williams, J. Wiss, K. W. Edwards, D. Besson, T. K. Pedlar, D. Cronin-Hennessy, K. Y. Gao, D. T. Gong, J. Hietala, Y. Kubota, T. Klein, B. W. Lang, S. Z. Li, R. Poling, A. W. Scott, A. Smith, S. Dobbs, Z. Metreveli, K. K. Seth, A. Tomaradze, P. Zweber, J. Ernst, A. H. Mahmood, H. Severini, D. M. Asner, S. A. Dytman, W. Love, S. Mehrabyan, J. A. Mueller, V. Savinov, Z. Li, A. Lopez, H. Mendez, J. Ramirez, G. S. Huang, D. H. Miller, V. Pavlunin, B. Sanghi, I. P. J. Shipsey, G. S. Adams, M. Cravey, J. P. Cummings, I. Danko, J. Napolitano, Q. He, H. Muramatsu, C. S. Park, W. Park, E. H. Thorndike, T. E. Coan, Y. S. Gao, F. Liu, M. Artuso, C. Boulahouache, S. Blusk, J. Butt, O. Dorjkhaidav, J. Li, N. Menaa, R. Mountain, R. Nandakumar, K. Randrianarivony, R. Redjimi, R. Sia, T. Skwarnicki, S. Stone, J. C. Wang, K. Zhang, S. E. Csorna, G. Bonvicini, D. Cinabro, M. Dubrovin, R. A. Briere, G. P. Chen, J. Chen, T. Ferguson, G. Tatishvili, H. Vogel, and M. E. Watkins

D. Besson, S. Anderson, V. V. Frolov, D. T. Gong, Y. Kubota, S. Z. Li, R. Poling, A. Smith, C. J. Stepaniak, J. Urheim, Z. Metreveli, K. K. Seth, A. Tomaradze, P. Zweber, K. Arms, E. Eckhart, K. K. Gan, C. Gwon, T. K. Pedlar, E. von Toerne, H. Severini, P. Skubic, S. A. Dytman, J. A. Mueller, S. Nam, V. Savinov, J. W. Hinson, G. S. Huang, J. Lee, D. H. Miller, V. Pavlunin, B. Sanghi, E. I. Shibata, I. P. J. Shipsey, D. Cronin-Hennessy, C. S. Park, W. Park, J. B. Thayer, E. H. Thorndike, T. E. Coan, Y. S. Gao, F. Liu, R. Stroynowski, M. Artuso, C. Boulahouache, S. Blusk, E. Dambasuren, O. Dorjkhaidav, R. Mountain, H. Muramatsu, R. Nandakumar, T. Skwarnicki, S. Stone, J. C. Wang, A. H. Mahmood, S. E. Csorna, I. Danko, G. Bonvicini, D. Cinabro, M. Dubrovin, S. McGee, A. Bornheim, E. Lipeles, S. P. Pappas, A. Shapiro, W. M. Sun, A. J. Weinstein, R. A. Briere, G. P. Chen, T. Ferguson, G. Tatishvili, H. Vogel, M. E. Watkins, N. E. Adam, J. P. Alexander, K. Berkelman, V. Boisvert, D. G. Cassel, J. E. Duboscq, K. M. Ecklund, R. Ehrlich, R. S. Galik, L. Gibbons, B. Gittelman, S. W. Gray, D. L. Hartill, B. K. Heltsley, L. Hsu, C. D. Jones, J. Kandaswamy, D. L. Kreinick, A. Magerkurth, H. Mahlke-Kruger, T. O. Meyer, N. B. Mistry, J. R. Patterson, D. Peterson, J. Pivarski, S. J. Richichi, D. Riley, A. J. Sadoff, H. Schwarthoff, M. R. Shepherd, J. G. Thayer, D. Urner, T. Wilksen, A. Warburton, M. Weinberger, S. B. Athar, P. Avery, L. Breva-Newell, V. Potlia, H. Stoeck, J. Yelton, B. I. Eisenstein, G. D. Gollin, I. Karliner, N. Lowrey, C. Plager, C. Sedlack, M. Selen, J. J. Thaler, J. Williams, and K. W. Edwards

The BaBar detector operated successfully at the PEP-II asymmetric e+e− collider at the SLAC National Accelerator Laboratory from 1999 to 2008. This report covers upgrades, operation, and performance of the collider and the detector systems, as well as the trigger, online and offline computing, and aspects of event reconstruction since the beginning of data taking.

We have updated our measurement of the cross section for e^+e^- -> psi(3770) -> hadrons, our publication "Measurement of sigma(e^+e^- -> psi(3770) -> hadrons) at E_{c.m.} = 3773 MeV", arXiv:hep-ex/0512038, Phys.Rev.Lett.96, 092002 (2006). Simultaneous with this arXiv update, we have published an erratum in Phys.Rev.Lett.104, 159901 (2010). There, and in this update, we have corrected a mistake in the computation of the error on the difference of the cross sections for e^+e^- -> psi(3770) -> hadrons and e^+e^- -> psi(3770) -> DDbar. We have also used a more recent CLEO measurement of cross section for e^+e^- -> psi(3770) -> DDbar. From this, we obtain an upper limit on the branching fraction for psi(3770) -> non-DDbar of 9% at 90% confidence level.

We report a measurement of the exclusive B+ meson decay to the D-s(()*K-)(+)pi(+) final state using 657 x 10(6) B (B) over bar pairs collected at the gamma(4S) resonance with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider. We use D-s* -> D-s(-) -> phi pi(-), (K) over bar*(892)K-0(-) and (KSK-)-K-0 decay modes for D-s(()*()) reconstruction and measure the following branching fractions: B(B+ -> Ds-K+pi(+)) = (1.71(-0.07)(+0.08)(stat)(-0.20)(+0.20)(syst) +/- 0.15(B-int)) x 10(-4) and B(B+ -> D-s*K--(+)pi(+)) = (1.31(-0.12)(+0.13)(stat)(-0.25)(+0.25)(syst) +/- 0.12(B-int)) x 10(-4). The uncertainties are due to statistics, experimental systematic errors, and uncertainties of intermediate branching fractions, respectively.

S. Dobbs, Z. Metreveli, K. K. Seth, A. Tomaradze, P. Zweber, J. Ernst, K. Arms, H. Severini, S. A. Dytman, W. Love, S. Mehrabyan, J. A. Mueller, V. Savinov, Z. Li, A. Lopez, H. Mendez, J. Ramirez, G. S. Huang, D. H. Miller, V. Pavlunin, B. Sanghi, I. P. J. Shipsey, G. S. Adams, M. Anderson, J. P. Cummings, I. Danko, J. Napolitano, Q. He, H. Muramatsu, C. S. Park, E. H. Thorndike, T. E. Coan, Y. S. Gao, F. Liu, M. Artuso, C. Boulahouache, S. Blusk, J. Butt, O. Dorjkhaidav, J. Li, N. Menaa, R. Mountain, K. Randrianarivony, R. Redjimi, R. Sia, T. Skwarnicki, S. Stone, J. C. Wang, K. Zhang, S. E. Csorna, G. Bonvicini, D. Cinabro, M. Dubrovin, A. Lincoln, A. Bornheim, S. P. Pappas, A. J. Weinstein, R. A. Briere, G. P. Chen, J. Chen, T. Ferguson, G. Tatishvili, H. Vogel, M. E. Watkins, J. L. Rosner, N. E. Adam, J. P. Alexander, K. Berkelman, D. G. Cassel, J. E. Duboscq, K. M. Ecklund, R. Ehrlich, L. Fields, R. S. Galik, L. Gibbons, R. Gray, S. W. Gray, D. L. Hartill, B. K. Heltsley, D. Hertz, C. D. Jones, J. Kandaswamy, D. L. Kreinick, V. E. Kuznetsov, H. Mahlke-Krüger, T. O. Meyer, P. U. E. Onyisi, J. R. Patterson, D. Peterson, E. A. Phillips, J. Pivarski, D. Riley, A. Ryd, A. J. Sadoff, H. Schwarthoff, X. Shi, M. R. Shepherd, S. Stroiney, W. M. Sun, T. Wilksen, M. Weinberger, S. B. Athar, P. Avery, L. Breva-Newell, R. Patel, V. Potlia, H. Stoeck, J. Yelton, P. Rubin, C. Cawlfield, B. I. Eisenstein, I. Karliner, D. Kim, N. Lowrey, P. Naik, C. Sedlack, M. Selen, E. J. White, J. Williams, J. Wiss, D. M. Asner, K. W. Edwards, D. Besson, T. K. Pedlar, D. Cronin-Hennessy, K. Y. Gao, D. T. Gong, J. Hietala, Y. Kubota, T. Klein, B. W. Lang, S. Z. Li, R. Poling, A. W. Scott, and A. Smith

Using the CLEO III detector at CESR we study e+e- collisions in the center-of-mass energy close to, or above, Lambda_b anti-Lambda_b production threshold. We search for evidence of Lambda_b anti-Lambda_b resonance production and set upper limits based on inclusive hadron production as a barometer of Lambda_b anti-Lambda_b production.