Introduction While research has extensively examined self-harm prevention and risk factors, fewer studies have explored recovery processes. Personally modifiable factors — lifestyle, skill-based, or behavioural aspects an individual can influence — may support self-harm recovery. This review aimed to identify these factors for young people and, secondarily, the barriers and facilitators affecting their implementation. Methods Recovery was defined symptomatically (reduction or cessation of self-harm) and personally, using the CHIME framework (Connectedness, Hope, Identity, Meaning, Empowerment). Five databases (Medline, CINAHL, PsycInfo, Embase, Web of Science) were searched in February 2025. Inductive coding identified personally modifiable factors, and the Consolidated Framework for Implementation Research (CFIR) guided analysis of barriers and facilitators. Results From 16,900 screened records, 35 studies were included. Common factors for symptom-based recovery (ceasing self-harm) included activities or hobbies (such as exercise, art, or music), social engagement with friends/family, harm minimisation techniques (e.g., holding ice cubes, elastic bands), and distraction methods. Online engagement and harm minimisation were double-edged, offering support but sometimes posing risks. Online forums fostered connectedness and empowerment, and recovery stories promoted hope (i.e. personal recovery). Barriers and facilitators varied; stigma often hindered offline discussion but encouraged anonymous online support. Conclusions Young people identify diverse, personally modifiable factors that guide self-harm recovery alone or with support. These factors are context- and person-dependent, underscoring the need for flexible, individualized approaches. Future research should also include low- and middle-income countries and include stratified analyses by sex and gender to capture a broader range of experiences and recovery pathways.

Introduction Discontinuation of psychotropic medication is associated with considerable clinical challenges, including withdrawal symptoms and relapse. Pharmacogenomic testing is increasingly used in clinical practice to optimise pharmacotherapy by guiding drug selection and dosing, however, its role in informing medication discontinuation and tapering strategies remains underexplored. Understanding the influence of genetic variability on withdrawal symptoms could support safer, individualised discontinuation practices. Objective This scoping review aims to map the available evidence on the role of pharmacogenomics on the discontinuation of psychotropic medications. Methods The review will be conducted in accordance with the Joanna Briggs Institute (JBI) methodology for scoping reviews and reported using the PRISMA-ScR checklist. Comprehensive searches will be performed in MEDLINE, EMBASE, CINAHL, Web of Science, and PsycINFO. Studies exploring gene polymorphisms relevant to the discontinuation of psychotropic medications (antidepressants, antipsychotics, mood stabilisers, anxiolytics, hypnotics, stimulants, and opioids) will be considered. Following screening, data will be extracted, and a narrative synthesis will be undertaken to map characteristics of included studies, genes studied, medication classes involved, reported outcomes, and knowledge gaps. Conclusion This review will provide an overview of existing evidence and identify gaps regarding the role of pharmacogenomics in psychotropic medication discontinuation. The findings will help to inform future research on the integration of pharmacogenomics into individualised tapering strategies.

Background Public and Patient Involvement (PPI) in mental health research is increasingly recognised as a moral and ethical imperative, necessary to increase the relevance and effectiveness of translation of research findings. Despite policy mandates and growing evidence of its benefits, PPI implementation in mental health research remains inconsistent. Little attention has been given to the state of scientific knowledge on PPI capacity strengthening in mental health research that can support more meaningful implementation. The aims of this scoping review are to: describe the content, implementation process, and theoretical underpinnings of PPI capacity-strengthening initiatives in mental health research; identify quantitative outcome measures and outcomes used to evaluate the initiatives’ impact on PPI contributors, research processes, and policy; and map barriers and enablers to the initiatives’ implementation. Methods This scoping review will follow JBI and PRISMA-ScR guidelines. Sources will include peer-reviewed articles, grey literature, and organisational materials describing training or skill-building initiatives for adult PPI contributors in mental health research. Searches will be conducted in MEDLINE, Embase, PsycINFO, and CINAHL, supplemented by hand-searching, targeted internet searches, and stakeholder consultation. Data extraction will capture descriptive details, initiative content, outcomes, and contextual factors, with barriers and enablers categorised according to the Consolidated Framework for Implementation Research (CFIR) domains. Conclusion This review will provide the first comprehensive synthesis of capacity-strengthening initiatives for PPI contributors in mental health research. Findings will inform the development of a co-designed blueprint for capacity-strengthening for PPI contributors, and progress broader efforts to embed lived experience expertise and general public perspectives equitably within mental health research systems.

Background Public and Patient Involvement (PPI) in mental health research is increasingly recognised as a moral and ethical imperative, necessary to increase the relevance and effectiveness of translation of research findings. Despite policy mandates and growing evidence of its benefits, PPI implementation in mental health research remains inconsistent. Little attention has been given to the state of scientific knowledge on PPI capacity strengthening in mental health research that can support more meaningful implementation. The aims of this scoping review are to: determine the state of knowledge concerning PPI in mental health research capacity-strengthening initiatives; identify the outcome measures used to evaluate the impact of capacity strengthening initiatives for PPI on contributors, research processes, and policy; and map the barriers and enablers to the implementation of capacity strengthening initiatives for PPI. Methods This scoping review will follow JBI and PRISMA-ScR guidelines. Sources will include peer-reviewed articles, grey literature, and organisational materials describing training or skill-building initiatives for adult PPI contributors in mental health research. Searches will be conducted in MEDLINE, Embase, PsycINFO, and CINAHL, supplemented by hand-searching, targeted internet searches, and stakeholder consultation. Data extraction will capture descriptive details, initiative content, outcomes, and contextual factors, with barriers and enablers categorised according to the Consolidated Framework for Implementation Research (CFIR) domains. Conclusion This review will provide the first comprehensive synthesis of capacity-strengthening initiatives for PPI contributors in mental health research. Findings will inform the development of a co-designed blueprint for capacity-strengthening for PPI contributors, and progress broader efforts to embed lived experience expertise and general public perspectives equitably within mental health research systems.

Introduction Discontinuation of psychotropic medication is associated with considerable clinical challenges, including withdrawal symptoms and relapse. Pharmacogenomic testing is increasingly used in clinical practice to optimise pharmacotherapy by guiding drug selection and dosing, however, its role in informing medication discontinuation and tapering strategies remains underexplored. Understanding the influence of genetic variability on withdrawal symptoms could support safer, individualised discontinuation practices. Objective This scoping review aims to map the available evidence on the role of pharmacogenomics on the discontinuation of psychotropic medications. Methods The review will be conducted in accordance with the Joanna Briggs Institute (JBI) methodology for scoping reviews and reported using the PRISMA-ScR checklist. Comprehensive searches will be performed in MEDLINE, EMBASE, CINAHL, Web of Science, and PsycINFO. Studies exploring gene polymorphisms relevant to the discontinuation of psychotropic medications (antidepressants, antipsychotics, mood stabilisers, anxiolytics, hypnotics, stimulants, and opioids) will be considered. Following screening, data will be extracted, and a narrative synthesis will be undertaken to map characteristics of included studies, genes studied, medication classes involved, reported outcomes, and knowledge gaps. Conclusion This review will provide an overview of existing evidence and identify gaps regarding the role of pharmacogenomics in psychotropic medication discontinuation. The findings will help to inform future research on the integration of pharmacogenomics into individualised tapering strategies.

OBJECTIVE:Child hunger is a significant global health concern prioritised by multiple global public health organisations. In 2006, the US Committee on National Statistics (CNSTAT) highlighted the need for clarity and consistency in the operationalisation and measurement of child hunger. This review examines whether these recommendations have been implemented in child nutrition programming over the past two decades. In addition, we explore how child hunger is currently conceptualised and measured across different contexts. DESIGN:We conducted a pre-registered rapid review of studies that define or measure 'child hunger'. Six electronic databases (Web of Science, MEDLINE, Embase, PsycINFO, Social Science Database and ERIC) and websites of twenty public health organisations were searched for reports that mentioned the term 'child hunger' or 'child' near 'hunger' published after 2006. SETTING:There were no restrictions on study settings. PARTICIPANTS:Studies focusing on children under the age of 18 years were included. RESULTS:Sixty-seven articles measured child hunger and were therefore eligible for inclusion. Of these, only twenty-three provided a definition of child hunger. Definitions commonly described child hunger as a consequence of or as a subcategory of household 'food insecurity'. Most scales used in the included studies examined the quantity or amount of food intake by children, while few measures also assessed the quality of food consumed. The physiological dimension of hunger was not measured by any of the questionnaires. CONCLUSIONS:The findings underscore the need for more comprehensive and standardised approaches that account for the multidimensional nature of child hunger.

To summarise the evidence regarding the impact of atopic dermatitis on adolescents and their families as well as their healthcare needs and to propose a nursing care plan based on the findings. Mixed-method systematic review. Twenty-four studies were included, of which 19 were quantitative and 5 were qualitative. The quality of the studies was assessed using the Mixed Methods Assessment Tool . The synthesis method used was data-driven convergent synthesis design. A systematic search was carried out in CINAHL, Embase, MEDLINE, PsycInfo and Web of Science without language restrictions from 1 January 2013 to 30 April 2023. The quality of life of adolescents with atopic dermatitis and their families are impaired. The more the severity of the condition, the greater the impact for them and their families. Atopic dermatitis impacts adolescents' sleep (due to itching), behaviour, mental well-being, social and school life. Likewise, parents' sleep, free time, interpersonal relationships and work life are affected by caring for their adolescents. Adolescents and their families encounter numerous challenges managing and living with atopic dermatitis on a daily basis. The condition has a widespread impact on adolescents and parents' quality of life across home, work and school settings. In the family, there was also an alteration in the functioning and relationships between its members. This review reveals the burden of atopic dermatitis for adolescents and families and the need for comprehensive support. Greater awareness among healthcare professionals of the impacts may help promote an evidence-based approach that supports the whole family. Based on these findings, we propose a nursing care plan based on the NANDA taxonomy to promote better healthcare provision for adolescents and families. This review adheres to PRISMA guidelines. No patient or public contribution. CRD42023435352.

Background Self-harm is the most important predictor of suicide, one of the leading causes of death in young people globally. There is a dearth of studies examining the processes underpinning recovery for those who have self-harmed. In particular, there is a lack of studies identifying elements that people who have self-harmed can change or influence to improve their wellbeing i.e. personally modifiable factors. Identifying these factors is important for individuals and clinicians to reduce or cease self-harm behaviours and improve personal wellbeing. In addition, it is imperative to understand why implementing these personally modifiable factors may succeed or fail. This systematic review has two aims: firstly, to identify personally modifiable factors for self-harm recovery in young people; and secondly, to identify the implementation determinants (barriers and facilitators) of these factors. Methods The search strategy will employ terms relating to three concepts (i.e. ‘young people’, ‘self-harm’, and ‘personally modifiable factors’) and will use five databases for the search process: Medline, CINAHL, APA PsycInfo, Embase, and Web of Science. At least two independent reviewers will conduct the screening process using eligibility criteria, followed by data extraction and quality assessment of the included studies. The mixed methods appraisal tool (MMAT) will be used for quality assessment. Inductive coding will be used to identify the personally modifiable factors and the Consolidated Framework for Implementation Research (CFIR) will be used to analyse and summarise the implementation determinants for these factors. Conclusion Identifying personally modifiable factors for self-harm recovery, and the barriers and facilitators underpinning their implementation, could inform the design of effective public health interventions to reduce self-harm in young people. Registration PROSPERO registration number CRD420250650920

This scoping review provides a broad overview of the existing literature on economic evaluations of preventive, screening, and treatment programmes for peripartum depression (PPD). PPD is one of the leading causes of disease-related disability among women. However, PPD often goes undiagnosed and untreated, with as many as half of cases not being identified. We followed the PICO-P (publication type) structure. Databases were searched from inception until 30 June 2023. The intervention stage in the studies was classified as prevention, screening, treatment, screening and treatment, and prevention and treatment. The health economics methods of the studies were divided into cost-effectiveness analysis, cost-utility analysis, cost-benefit analysis, cost-minimisation analysis, return of investment, and multiple. Ultimately, 38 studies were included for extraction and evaluation. Several interventions for PPD may be cost effective, including peer support, psychological therapies, and screening strategies using tools like the Edinburgh Postnatal Depression Scale (EPDS). However, study limitations include heterogeneity across studies, methodological limitations, and limited generalisability to diverse populations. The cost-effectiveness results of PPD interventions may differ across different health systems, partly due to differences in the amount and distribution of resources available. By implementing suggested policy recommendations, policymakers can significantly improve the identification, treatment, and prevention of PPD, ultimately improving the health and well-being of mothers, children, and families.

Inspection of social work services aims to improve accountability and the quality of services, but inspection can also have unwanted consequences. This paper presents findings from a rapid review of the literature on the effects of regulatory inspection on child and family services. We searched two electronic databases, websites of national inspectorates in Ireland, Great Britain and Northern Ireland and used reference chaining of extracted publications. Sources were methodologically appraised using the Mixed Methods Appraisal Tool (MMAT). We screened 5142 sources. Fourteen sources met eligibility criteria for extraction. The review found that inspection can encourage timeliness, documentation of process and identify poor practice. However, inspection may also drive unwarranted statutory intervention in families' lives. Practitioners can experience inspection as anxiety-inducing and time-consuming, and negative inspection judgments sometimes destabilize services. Inspection of child and family services can create both beneficial and dysfunctional effects and systems should be monitored to identify these.

Objectives This scoping review aimed to map studies on behaviour change interventions that address antibiotic treatment-seeking behaviour for respiratory tract infections in primary and community care settings.Design This review is based on the Joanna Briggs Institute guidelines for scoping reviews, guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews.Data sources A literature search in January 2024 and May 2024 was performed across Medline, Embase, CINAHL, PsycINFO, Web of Science Core Collection, Scopus, EThOS and Google Scholar was performed.Eligibility criteria Eligible studies described behaviour change interventions in primary and community care settings, published from 2000 onward across all countries.Data extraction and synthesis Descriptive data relating to study details and intervention functions were gathered and organised according to the Capability, Opportunity, Motivation and Behaviour change framework in a predeveloped data extraction sheet. Dual data extraction occurred, and inter-rater reliability results are reported (K=0.83).Results The scoping review identified 38 eligible studies, which consisted of randomised controlled trials (7/38), cluster randomised controlled trials (6/38), randomised experiments (5/38), cross-sectional studies (5/38), qualitative investigations (5/38) and quasi-experimental designs (4/38). Most interventions focused on educational resources (15/38), digital tools (7/38) and community campaigns (6/38), with fewer targeting decision-making processes (4/38) or psychological drivers of antibiotic-seeking behaviour (3/38). Only one study was conducted in low-income and middle-income countries, and only one separately assessed behaviour change as a measured outcome.Conclusions This scoping review highlights a wide range of research methodologies within the topic area. There was some limited evidence of intervention efficacy for antibiotic prescription rates, particularly interventions focused on enhancing knowledge and access to resources. However, more emphasis is needed on standardising outcome measures and evaluating long-term outcomes.

Suicide remains one of the leading causes of death globally, with growing evidence that humanitarian emergencies and fragile states, most of which unfold in low- to middle-income countries (LMICs), are associated with elevated risk of suicide. However, the few suicide-targeted interventions for use in humanitarian contexts remain both sparse and fragmented. This scoping review aims to identify and synthesise evidence from suicide and self-harm prevention interventions implemented in all types of humanitarian settings, globally, that have been evaluated for their effectiveness in improving suicide and self-harm-related outcomes. We systematically searched eight electronic databases, including two grey literature databases, and relevant organisational websites for records published through November 2024 and in any language. Screening was done using the Covidence platform, with each record independently screened by two reviewers. Among other preselected inclusion criteria, studies must have conducted a quantitative evaluation of the effectiveness of an intervention on improving suicide and self-harm-related outcomes during a humanitarian crisis to be included for data extraction. Data extraction and quality assessment were both conducted by two authors. In all, 6,209 records were screened at the title and abstract phase; 104 were included for full text screening; and 23 studies were included for data extraction. Most studies were conducted during the coronavirus disease 2019 pandemic (COVID-19), and in high-income countries. Evaluated interventions encompassed various approaches, including psychotherapeutic, practical, and pharmacological assistance, often employing multiple components. The majority targeted the general population, were delivered via remote modalities and relied on mental health specialists for their administration. Overall, 15 (65.2%) interventions were associated with statistically significant positive effects on suicide and or self-harm-related outcomes. Promising approaches include cognitive behavioural therapy-based text services, skills-building programmes, and strategies that foster supportive environments for high-risk individuals. These findings highlight both promising approaches and critical gaps in suicide prevention efforts in humanitarian settings. The limited evidence base - particularly in LMICs and with particularly at-risk populations - alongside the increasing frequency of humanitarian crises, underscores the urgent need for future implementation and associated research of suicide and self-harm prevention initiatives within humanitarian contexts.

Background Adolescence is a period of transition in which young people undergo physical, psychological and social changes. While most move through this transition with few problems, others experience greater difficulties, which may lead to an increased risk of becoming vulnerable to mental health issues. Social media use amongst young people is high; an abundance of literature identifies the deleterious impact of its use on mental health. However, its positive influence on youth well-being is also reported. Ireland’s mental health policy recommends harnessing the positive role social media can play in the promotion of youth mental health. However, an evidence gap exists as to how this can be implemented. This scoping review aims to identify the barriers and enablers to the use of social media as a youth mental health promotion tool, to inform the implementation of policy recommendations. Methods The search strategy, screening, extraction and synthesis will be informed by the JBI guidelines. The Consolidated Framework for Implementation Research will guide the identification and mapping of implementation determinants. The review outcomes will be reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews guidelines. Primary studies focused on young people and key stakeholders, such as teachers and parents, identifying barriers and enablers to the use of social media for youth mental health promotion will be included. A librarian-developed search strategy will be applied to the Web of Science Core Collection, Medline (EBSCO), Embase, PsycINFO and CINAHL databases. A narrative synthesis of the results guided by CFIR framework will be presented. Conclusion The review extends the work of previous reviews by adopting an Implementation Science approach focusing on the identification and mapping of implementation barriers and enablers to the use of social media as a youth mental health promotion tool. Registration Open Science Framework ( https://doi.org/10.17605/OSF.IO/T5YF7M )

BACKGROUND:Woman/person-centred care is a key policy objective for maternity services in many high-income countries, both strategically and in terms of service delivery. This approach to care prioritises the individual woman's needs and aspirations over those of professionals or institutions. However, the concept remains ambiguous and practical implementation guidelines are lacking, leading to concerns that it is being practised tokenistically. AIM:To explore how woman-centred care in maternity services in high-income countries is experienced and understood by women and professionals. METHODS:A rapid review was conducted to synthesise evidence on woman-centred care from women's and clinicians' perspectives. Five bibliographic databases, CINAHL, Maternity and Infant Care, MEDLINE, PsycINFO and Web of Science, were searched systematically in December 2023. Citations eligible for inclusion were peer-reviewed quantitative, qualitative and mixed-methods empirical studies conducted in high-income countries and literature reviews reporting on studies conducted in high-income countries. Title and abstract screening, full-text screening, data extraction and quality appraisal were performed, with 10% of records double-screened to ensure consistency and minimise bias. Methodological quality was assessed using the Mixed Methods Appraisal Tool. Extracted data were synthesised thematically. FINDINGS:In total, 5295 records were retrieved; after deduplication, 2707 records were screened, and 24 studies met the inclusion criteria. The review identified inconsistencies in how woman-centred care was experienced and understood at all levels of service provision, from policy directives to institutional practices. Diverse understandings of woman-centred care among stakeholders were found to influence interactions. Several studies revealed that professionals' varying interpretations affected their attitudes and approaches to care, while some women were found to hold differing expectations about woman-centred care provision. CONCLUSION:To realise the policy intention of woman-centred care, further context-specific investigations are needed to provide evidence and evaluation to inform implementation strategies.

INTRODUCTION:There is an increasing drive to implement new non-professionally affiliated psychosocial support roles within multidisciplinary teams (MDT) to improve the integration of care. This is to enhance holistic care and extend the historic focus of care beyond the patient, to the family and community, however, determinants that impact on the implementation of these roles have yet to be reviewed. METHODS:The aim of the scoping review was to identify determinants impacting the implementation and sustainability of these roles within MDTs. The review was informed by the Joanna Briggs Institute framework and the 'Preferred Reporting Items for Systematic Reviews and Meta-Analysis'. Using a pre-defined search strategy, CINAHL, Medline, PsycInfo, and Web of Science databases were searched. Identified studies were screened using Covidence ( www.covidence.org/ ). Data extraction and analysis involved three phases: data extraction using the Consolidation Framework for Implementation Research (CFIR); identifying and classifying determinants; developing explanatory themes beyond CFIR using thematic analysis. RESULTS:A total of 4232 papers remained after deduplication. Twenty-four papers met the inclusion criteria. Four themes were identified: new role boundaries; two sides to the worker - patient/client relationship; environmental preparedness; and role holder characteristics. Role boundary issues due to deficits in role clarity lack of training for the role holder, and information for wider team, were significant barriers to implementation and sustainability. Mentorship and training, which developed role holders' skills and confidence as well as role holders' personal characteristics, life experience, the flexibility of their role, and having time to spend with patients/clients were significant enablers. CONCLUSION:There is a need for greater attention to role clarity and boundary working during the design phase of roles and as an aspect of environmental preparedness, especially with MDT members. The provision of training specific to new roles, and support in the form of mentorship, are necessary to develop the required skills and confidence in new role holders. Given the considerable heterogeneity in the aims and objectives of research on new psychosocial roles not affiliated to a profession or discipline an absence of studies focusing on the determinants of the implementation, integration, and sustainability of these roles, more research is needed to support their future implementation.

Due to an increased awareness of the prevalence and impact of trauma, "trauma-informed care" (TIC) was developed as an organisational framework aiming to centre the needs of survivors of trauma. TIC proposes that organisations can reduce trauma exposure by embedding specific principles (e.g., safety and trust) at every level of an organisation, improving the organisation for both service users and providers. Recent reviews of TIC implementation efforts have demonstrated its use in diverse settings; however, studies are overwhelmingly situated in high-income, predominantly English-speaking countries. Rather than reflecting a lack of TIC efforts in low- and middle-income countries (LMICs), these findings may be a result of the newness of the term TIC. To create a more inclusive evidence map, the current review captures efforts conducted in LMICs that may or may not use the label of TIC but align with the organisational approaches and key principles of TIC. A search of four databases and review of relevant references yielded 3,091 results, of which 255 met the inclusion criteria. Implementation efforts took place across 39 LMICs. The vast majority included involvement of another country, most commonly the United States. Approximately 90% of efforts were implemented within medical settings, and 69% focused on the TIC principle of cultural, historical and gender issues. The results of the current review have both theoretical and applied implications for TIC research. They query how and by whom TIC is conceptualised and defined, and how TIC aligns with other global research approaches. Results also highlight the need for organisational TIC interventions to conduct comprehensive baseline assessments of current efforts before implementing new efforts to avoid unintentional duplication. As the adoption of TIC frameworks becomes more widespread, it is imperative to increase research efforts aimed at developing a more thorough and inclusive definition of TIC.

Background Approximately one in eight people live with mental health difficulties, with onset commonly occurring in youth. It is critical to ensure care addresses all aspects of health, including physical health and sexual wellbeing needs, to achieve positive recovery outcomes. Connecting primary and secondary healthcare providers and service users through shared models of care is a critical aspect of this. The objectives of this scoping review will be to 1) identify and describe the implementation of shared models of care which address the mental health of young people and their physical health and/or sexual wellbeing needs, and 2) identify the determinants of implementing these models of care. Protocol Following Joanna Briggs Institute guidelines, studies will be included if they describe shared models of care for young people (aged 10–25) in any healthcare setting, specifically addressing mental health and physical health or sexual wellbeing needs. The review will employ the Consolidated Framework for Implementation Research (CFIR) to organise and assess findings. A librarian developed the search strategy, which will be applied to Web of Science, Medline, Embase, CINAHL, and PsycINFO databases. Two independent reviewers will screen titles, abstracts and full texts, followed by data extraction and critical appraisal of included studies. Discrepancies at all stages will be resolved through discussion or by a third reviewer. Screening results will be summarised in a PRISMA flow diagram. Narrative summaries, supported by tables and figures where applicable, will address the review’s objectives. Findings will undergo thematic analysis, with implementation determinants mapped deductively to CFIR. Discussion Findings will inform the adaptation of implementation strategies to support the implementation of policy for improving healthcare delivery to young people with mental health difficulties. Registration Open Science Framework (osf.io/rj783).

AIMS:To summarise the evidence regarding the impact of atopic dermatitis on adolescents and their families as well as their healthcare needs and to propose a nursing care plan based on the findings. DESIGN:Mixed-method systematic review. METHODS:Twenty-four studies were included, of which 19 were quantitative and 5 were qualitative. The quality of the studies was assessed using the Mixed Methods Assessment Tool. The synthesis method used was data-driven convergent synthesis design. DATA SOURCES:A systematic search was carried out in CINAHL, Embase, MEDLINE, PsycInfo and Web of Science without language restrictions from 1 January 2013 to 30 April 2023. RESULTS:The quality of life of adolescents with atopic dermatitis and their families are impaired. The more the severity of the condition, the greater the impact for them and their families. Atopic dermatitis impacts adolescents' sleep (due to itching), behaviour, mental well-being, social and school life. Likewise, parents' sleep, free time, interpersonal relationships and work life are affected by caring for their adolescents. CONCLUSION:Adolescents and their families encounter numerous challenges managing and living with atopic dermatitis on a daily basis. The condition has a widespread impact on adolescents and parents' quality of life across home, work and school settings. In the family, there was also an alteration in the functioning and relationships between its members. IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE:This review reveals the burden of atopic dermatitis for adolescents and families and the need for comprehensive support. Greater awareness among healthcare professionals of the impacts may help promote an evidence-based approach that supports the whole family. Based on these findings, we propose a nursing care plan based on the NANDA taxonomy to promote better healthcare provision for adolescents and families. REPORTING METHOD:This review adheres to PRISMA guidelines. PATIENT OR PUBLIC CONTRIBUTION:No patient or public contribution. REVIEW REGISTRATION (PROSPERO ACCORDING TO JAN GUIDELINES):CRD42023435352.

Background Benzodiazepine receptor agonists (BZRAs) are commonly prescribed to treat anxiety and insomnia. Although guidelines recommend limiting prescriptions to short-term use (<4 weeks), BZRAs are often continued long-term. Due to the associated risks (e.g. memory impairment, falls/fractures), it is recommended that long-term BZRA use should be discontinued. Several systematic reviews have studied the effectiveness of pharmacological and non-pharmacological interventions targeting long-term BZRA use; however, an overview of the evidence across intervention types and healthcare settings is lacking. Aim To identify and narratively synthesise systematic reviews that assess the effectiveness of interventions targeting the reduction or discontinuation of long-term BZRA use. Methods An overview of systematic reviews will be conducted. Five electronic databases (MEDLINE, Embase, Web of Science, PsycINFO, CINAHL) will be searched for systematic reviews of randomised controlled trials of interventions targeting the reduction or discontinuation of long-term BZRA use in adults in any setting. All types and combinations of interventions are eligible for inclusion (e.g. psychosocial interventions, pharmacological interventions). Interventions will be evaluated against usual care. Article screening and data extraction will be conducted by two reviewers independently. Overlap in primary publications will be assessed by calculating the corrected covered area and graphically represented. Methodological quality of included reviews will be assessed using the AMSTAR-2 tool. Results will be synthesised narratively. The certainty of evidence will be assessed using the GRADE approach. Conclusions This overview of reviews will narratively synthesise the evidence from systematic reviews of the effectiveness of interventions targeting long-term BZRA use. The review will provide an extensive overview of the existing evidence, which will inform future research and policy decisions about interventions for reducing and discontinuing long-term BZRA use.