The basic idea of panoptical control is that people will obey the prevailing rules and norms when they know they are being watched. The theory was developed by Jeremy Bentham 200 years ago when he designed an architecturally and managerially innovative model prison called Panopticon. Along with his Utopian Panopticon-poorhouse scheme, Bentham's vast plans have been viewed as the most thorough combination of physical and social engineering ever devised. The various elements of panoptical control theory received their most systematic realization in George Orwell's Nineteen Eighty-four. The novel serves to illustrate the theory and also to suggest Orwellian overtones to Bentham's plans, which were quite antithetical to his Utilitarian philosophy.

Recent research has shown that rats exposed to repeated stress display enhanced morphine analgesia. This study examined the possible contribution of classically conditioned analgesia to this effect. First, drug-naive rats exposed to nine daily sessions of stress, each consisting of a single 45-s exposure to footshock, subsequently displayed enhanced analgesic responsiveness to morphine 1 and 10 days after stress (Experiments 1, 2, and 5). This enhancement was also observed in morphine-experienced rats 1 and 8 days after stress (Experiment 1). Second, the effect of footshock stress on morphine analgesia was found to be specific to the environment in which stress was administered (Experiments 2 and 3). Rats tested in the same distinctive environment in which stress was administered displayed enhanced morphine analgesia; rats shocked elsewhere did not differ from nonshocked controls (Experiment 2). Third, conditioned analgesia was found under the same conditions that yielded enhanced morphine analgesia (Experiments 2 and 4). Lastly, both this conditioned analgesia and the acute analgesia elicited by the footshock stressor were found to be attenuated by naloxone (Experiments 5 and 6). These data are consistent with the hypothesis that the enhanced morphine analgesia observed after repeated footshock stress reflects the contribution of an opioid mediated , conditioned analgesia elicited by cues formerly paired with the stressor.

The associative model of morphine tolerance predicts that established tolerance should be attenuated, i.e., extinguished, by placebo injections in the former morphine injection environment. The present study examined the effect of placebo sessions, with and without accompanying nociceptive stimulation, on the extinction of analgesic tolerance. In Experiment 1, rats rendered tolerant to morphine displayed recovery of morphine's analgesic action only following placebo sessions including exposure to a painful hot plate surface (52.5°C); placebo sessions on a cool plate (23–24°C) failed to attenuate tolerance even though these placebo sessions more closely matched the stimulus conditions of tolerance acquisition. In Experiment 2, repeated hot plate exposures were similarly found to enhance morphine analgesia in drug-naive rats. These results question an extinction account of the effect of hot plate placebo sessions observed in Experiment 1. Instead, they suggest that nociceptive hot plate exposures, per se, are sufficient to enhance subsequent morphine analgesia.

An experiment was performed to test the hypothesis that in a voluntary generalization task subjects encode the training stimulus (TS) in relation to the adaptation-level (AL) prevailing at the time of TS presentation. If so, then during a subsequent generalization test the point of maximal generalized responding should bear this same relationship to the AL of the generalization test series. To test this hypothesis, three major groups of subjects (n = 80) were given preexposures with dim lights (low preexperimental AL group), bright lights (high preexperimental AL group), or no preexposure (control group). Next, half of each group was exposed to a TS and a subsequent generalization (recognition) test including this brightness and four others. The other half of each group was exposed to the same TS and subsequent generalization stimuli, but their task was to rate the stimuli on a 7-point bright-dim scale. This provided AL measures which could be correlated with generalization performance in the comparable generalization groups. The preexposure condition was successful in producing the expected low or high preexperimental ALs, as reflected in different ratings of the TS when it was presented. Furthermore, these effects persisted throughout testing, as evidenced in ALs (i.e., rating scale midpoints) which reflected the preexposure condition. Finally, the difference between the point of maximal generalized responding and the AL of the generalization test series was highly and significantly correlated with the difference between the original rating of the TS and scale midpoint. This supports the maj or experimental hypothesis of the study.

Rats were trained in an operant discrimination involving two panel lights, A and B. Group CI (Conditioned Inhibition) was trained to lever press in the presence of A (S+), and not in the presence of the compound AB (S−). The opposite contingencies held in Group CE (Conditioned Excitation). Response rates were higher in Group CE than in Group CI, especially to the positive stimulus. However, the groups acquired the discrimination at comparable rates. In a separate phase of the experiment, a tone (C) was separately trained in the absence of the lights to control responding. All seven possible combinations of A, B, and C were then presented randomly during extinction. The inhibitory effect of B on C in Group CI was comparable in magnitude to the excitatory effect of B on C in Group CE. B's effect on C was not altered by the presence or absence of A, regardless of whether A was inhibitory or excitatory. The symmetry between CI and CE revealed by the stimulus-compounding test may be partly artifactual.