ChemInformVolume 20, Issue 5 Natural Products ChemInform Abstract: Total Synthesis of Pseudomonic Acid C (I). J. C. BARRISH, J. C. BARRISH Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this authorH. L. LEE, H. L. LEE Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this authorT. MITT, T. MITT Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this authorG. PIZZOLATO, G. PIZZOLATO Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this authorE. G. BAGGIOLINI, E. G. BAGGIOLINI Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this authorM. R. USKOKOVIC, M. R. USKOKOVIC Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this author J. C. BARRISH, J. C. BARRISH Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this authorH. L. LEE, H. L. LEE Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this authorT. MITT, T. MITT Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this authorG. PIZZOLATO, G. PIZZOLATO Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this authorE. G. BAGGIOLINI, E. G. BAGGIOLINI Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this authorM. R. USKOKOVIC, M. R. USKOKOVIC Chem. Res. Dep., Hoffmann-La Roche, Inc., Nutley, NJ 07110, USASearch for more papers by this author First published: January 31, 1989 https://doi.org/10.1002/chin.198905313AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume20, Issue5January 31, 1989 RelatedInformation

A novel approach to d-biotin from cysteine, which a utilizes the nitrate oxide To enolthioether double bond cyclization for the formation of C2-C3 of the thiophane ring and the incorporation of the 3-N in the biotin molecule, Is described. the cis relation of the n-butyl side chain and the sulfur in respect to isoxazolidine ring in the bicycle diastereomers 9 And 12 is characterized by an NMR signal For The α- methylene protons of the side chain as a multiplelet at δ1.82 AND 1.80, respectively, ownfield from the multiplet at 1.33 AND 1.32, respectively, for the other two methylenes of the side chain.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTotal synthesis of pseudomonic acid CJoel C. Barrish, Hsi Lin Lee, Toomas Mitt, Giacomo Pizzolato, Enrico G. Baggiolini, and Milan R. UskokovicCite this: J. Org. Chem. 1988, 53, 18, 4282–4295Publication Date (Print):September 1, 1988Publication History Published online1 May 2002Published inissue 1 September 1988https://pubs.acs.org/doi/10.1021/jo00253a021https://doi.org/10.1021/jo00253a021research-articleACS PublicationsRequest reuse permissionsArticle Views1388Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

AbstractPseudomonic acid C (V) is synthesized from the hydroxycyclopentenylacetate (I) via the key intermediates (II) ‐ (IV).

AbstractBeschrieben wird die Synthese der Titelverbindung (Xd), ausgehend von dem Dimethylester (I).

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTotal synthesis of Cinchona alkaloids. 1. Synthesis of meroquineneMilan R. Uskokovic, Thomas Henderson, Charles Reese, Hsi Lin Lee, Guenter Grethe, and Juerg GutzwillerCite this: J. Am. Chem. Soc. 1978, 100, 2, 571–576Publication Date (Print):January 1, 1978Publication History Published online1 May 2002Published inissue 1 January 1978https://pubs.acs.org/doi/10.1021/ja00470a035https://doi.org/10.1021/ja00470a035research-articleACS PublicationsRequest reuse permissionsArticle Views888Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

AbstractUmsetzung des optisch aktiven Carbaldehydes (Ia) mit dem Li‐Reagenz (II) [erzeugt aus 4‐Brom‐6‐methoxy‐chinolin und Bu‐Li in Ether bei ‐70°C ] und anschließende Hydrolyse ergibt Chinin (IIIa), Chinidin (IVa), Epichinin (Va) und Epichinidin (VIa); unter analogen Bedingungen werden aus dem optisch aktiven Aldehyd (Ib) bzw. aus dem Racemat (Ic) die Verbindungen (IIIb)‐(VIb) bzw. die Racemate (IIIc)‐(VIc) erhalten.

Abstractβ‐Kollidin (I) reagiert mit Chloral zu dem Dichlorchlorhydrin (i)‐(II), dessen katalytische Hydrierung in Gegenwart von HCl zu den Racematen der Diastereoisomeren (IIIa) und (IIIb) führt.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTotal synthesis of Cinchona alkaloids. 3. Syntheses of quinuclidine intermediatesGuenter Grethe, Hsi Lin Lee, Toomas Mitt, and Milan R. UskokovicCite this: J. Am. Chem. Soc. 1978, 100, 2, 581–588Publication Date (Print):January 1, 1978Publication History Published online1 May 2002Published inissue 1 January 1978https://doi.org/10.1021/ja00470a037RIGHTS & PERMISSIONSArticle Views633Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alerts Get e-Alerts

AbstractEine stereospezifische Totalsynthese von Merochinen (X) wird beschrieben.

Cinchona‐Alkaloide. Totalsynthese von Cinchonamin. – Zusammenfassung. Zwei verschiedene Wege zur Totalsynthese des Cinchona‐Alkaloids Cinchonamin (1) und seines C(2)‐Epimers (24) werden beschrieben. Als Ausgangsmaterial diente synthetisch hergestelltes N‐Benzoylmerochinen (2) oder sein Methylester 15.

AbstractIn der vorläufigen Mitt. wird die Totalsynthese auf zwei verschiedenen Wegen von Cinchonamin (IIa) und seines 2‐Epirneren (IIb) beschrieben.

AbstractEine neue Synthese von N‐benzoyl‐homomerochinen‐äthylester (10 b) und dessen Überführung in Chinotoxin (18) wird beschrieben.