One-lung ventilation (OLV) is essential in some surgical situations. The use of double- lumen tubes (DLTs) can achieve OLV more quickly and more easily than bronchial blockers. The management of a difficult airway is a challenge for anesthesiologists when, at the same time, OLV is needed for a surgical procedure. This report describes the successful application of DLTs in two patients with difficult airways, and who were scheduled for pulmonary decortication. Case 1 already had a permanent tracheostomy, while Case 2 had oral cancer with an extremely limited mouth opening and needed elective tracheostomy for anesthesia. Nasal intubation of Case 2 was done with fiberoptic-guided intubation with the patient awake. OLV was achieved uneventfully after inserting the DLT directly through the tracheostomy in both cases. We also describe the appropriate use of airway devices for OLV, focusing on patients with an anticipated difficult airway.

BACKGROUND:A combination of antiemetic drugs could be an effective method to prevent severe postoperative nausea and vomiting (PONV). Therefore, we examined the prophylactic effect of haloperidol plus ondansetron on PONV.METHODS:We enrolled 210 patients (n = 70 in each of 3 groups) undergoing elective laparoscopic cholecystectomy for this randomized double-blind study. Patients were randomized to intravenous saline 2 mL and intramuscular haloperidol 2 mg (Group H), intravenous ondansetron 4 mg and intramuscular saline 2 mL (Group O), or intravenous ondansetron 4 mg and intramuscular haloperidol 2 mg (Group H+O), administered after induction of general anesthesia and 30 minutes before the conclusion of surgery. We compared the complete response rates, incidence of PONV, nausea scores, the need for rescue medication, patient satisfaction scores, and adverse events during the 24-hour study.RESULTS:The H+O group had the highest complete response rate to treatment (79%) compared with group H (61%) and group O (62%) (p < 0.05 for both). Patient satisfaction scores were significantly higher in the H+O group (8.3 +/- 1.8) than in the H (7.0 +/- 2.4) and O (7.2 +/- 2.5) groups (p < 0.05 for both). In addition, nausea scores were significantly lower in the H+O group (1.2 +/- 2.6) than in the H (2.5 +/- 3.3) and O (2.2 +/- 3.1) groups (p < 0.05 for both).CONCLUSION:We conclude that the combination of prophylactic haloperidol (2 mg) plus ondansetron (4 mg) provides a higher complete response rate and greater patient satisfaction after laparoscopic cholecystectomy than either drug used alone.

We report the perioperative airway management in a 12-year-old boy suffering from Treacher Collins syndrome (TCS) and severe mental retardation who was scheduled for elective dental treatment under general anesthesia. TSC is also known as mandibulofacial dysostosis or Franceschetti syndrome, usually with a potentially difficult airway presentation. It is a major challenge for the anesthesiologist to manage an uncooperative child with such a congenital airway anomaly. A difficult airway was en countered during induction of general anesthesia, and both oral intubation by direct laryngoscopy and classic laryngeal mask airway (LMA) insertion were unsuccessful. In an expedient critical trial, with the cooperation of two anesthesiologists, one performing nasal fiberoptic intubation and the other maintaining oral mask ventilation, a nasal endotracheal tube was successfully placed at the first attempt, although at the expense of prolonged respiratory depression in the patient. Therefore, fiberoptic nasal intubation simultaneously with mask ventilation for placement of the endotracheal tube is a practical substitute for a difficult airway usually managed by LMA with inadequate ventilation. After extubation, tracheostomy may be indicated if the TCS patient suffers from persistent difficult upper airway in consequence of a traumatic intubation.

OBJECTIVE:Catheterization of the internal jugular vein (IJV) after placement of a laryngeal mask airway (LMA) has been reported to be difficult. The purpose of this study was to evaluate the accuracy of the central landmark for catheterization of the right IJV after placement of a ProSeal LMA.METHODS:We enrolled 80 patients (30 men and 50 women) who were scheduled to undergo surgery under general anesthesia conveyed by a size 3 ProSeal LMA. A needle pathway based on the central landmark for right IJV catheterization was simulated. Ultrasound images were obtained, which we contrasted with the simulated pathway to evaluate whether the landmark accuracy remained unchanged after placement of the ProSeal LMA. Both frequency of simulated right carotid artery (CA) puncture and overlap between the right IJV and right CA were also investigated.RESULTS:The simulated needle pathway ran along the course of the right IJV in 60% (48/80) of subjects, and transected the CA in 31.3% (25/80) of subjects. Both events together occurred in 20% (16/80) of subjects. The central landmark had a medial bias of 6.8 mm (95% confidence interval, 5.3-8.4). In 83.8% (67/80) of subjects, the center of the right IJV was lateral to the central landmark. The possibility of overlap of the right IJV and CA was high after ProSeal LMA placement.CONCLUSION:After placement of the ProSeal LMA, the central landmark could not offer a good success rate at the first puncture attempt. When using the central landmark to catheterize the IJV after a ProSeal LMA placement, medial deviation of the central landmark should be considered. Ultrasound guidance may be helpful in difficult cases.

BACKGROUND:Identification of recurrent laryngeal nerve (RLN) has decreased the rates of permanent RLN palsy during thyroid operations; however, unexpected RLN palsy still occurs, even though the visual integrity was assured and most nerve injuries were not recognized intraoperatively. The aim of this study is to determine the causes of RLN palsy and to identify potentially reversible causes of RLN injury during the operation with the application of intraoperative neuromonitoring (IONM).METHODS:One hundred and thirteen patients with 173 nerves at risk were enrolled in this study. All operations were performed by the same surgeon. The 4-step procedure of IONM was designed to obtain electromagnetic (EMG) signals from the vagus nerve and RLN before and after resection of thyroid lobe.RESULTS:Sixteen nerves had loss of EMG signals after thyroid dissection, and the causes of nerve injuries were well elucidated with the application of IONM. One nerve injury was caused by inadvertent transection, which led to permanent RLN palsy. Among the remaining 15 nerves, 1 injury was caused by a constricting band of connective tissue, which was detected precisely and released intraoperatively, 2 by inadvertent clamping of the nerve, and 12 by apparent overstretching at the region of Berry's ligament. (Five nerves regained signals before closing the wound, but 1 showed impaired cord movement. Another 7 nerves did not regain signals before closing the wound, and all developed temporary RLN palsy.)CONCLUSIONS:Our 4-step procedure of IONM is useful and helpful in elucidating the potential operative pitfalls during dissection near the RLN. Although the rates of RLN palsy were not decreased in this study, the use of neuromonitoring provided instructive information for future operations by ascertaining where and how the RLN has been injured.

Anesthesia during laryngeal surgery presents the anesthesiologist with a number of potential challenges. It requires cooperation between the surgeon and anesthesiologist in order to maximize exposure for the surgeon and allow for adequate ventilation of the patient. Many anesthetic techniques have been used such as jet ventilation (subglottic or supraglottic) and endotracheal intubation (intermittently or continuously), with a variety of tubes. We present our experience of successful airway management with the assistance of the Cook® airway exchange catheter during microlaryngeal surgery. [Tzu Chi Med J 2008;20(1):73–75]

BACKGROUND:Malpositioning of the endotracheal surface electrodes can result in dysfunction of intraoperative neuromonitoring (IONM) and increase the risk of recurrent laryngeal nerve injury. The purpose of this study was to investigate the optimal depth of the nerve integrity monitor (NIM) EMG endotracheal tube.METHODS:We enrolled 105 adult patients undergoing elective thyroidectomy. Each Medtronic Xomed NIM EMG endotracheal tube was placed with the middle of the exposed electrodes well in contact with the true vocal cords under direct laryngoscopy. Function of IONM was documented and the insertion depth was measured and analyzed.RESULTS:Ninety-nine (94.3%) patients had successful IONM with the initial endotracheal tube position. Six (5.7%) patients needed further tube depth adjustment under fiberoptic bronchoscopy. All patients were finally had successful IONM. The optimal mean depth was 20.6 +/- 0.97 cm in men and 19.6 +/- 1.0 cm in women (p < 0.01). There was the trend that taller subjects had a deeper tube depth (p < 0.05).CONCLUSION:We concluded that the mean depth of the NIM EMG tube would be a useful reference value for detecting the malposition of electrodes and adjusting the depth of tube during the operation.

A 34-year-old man was referred to our hospital for management of multiple trauma in consequence of a car accident. Initial examination showed mild intracranial hemorrhage proven by computed tomographic scan (CT) of the brain and multiple fractures of face and thigh. Surgical repair of the multiple fractures was undertaken with stable vital signs and neurological condition. Anesthesia was induced with fentanyl and thiamylal and rocuronium was used to facilitate oroendotracheal intubation. Sevoflurane in a mixture of oxygen and air and rocuronium were used for maintenance of anesthesia and surgical relaxation, respectively. The surgeon decided to perform fixation of facial bone first, so he infiltrated the nasal mucosa with epinephrine solution to minimize blood loss. After the operation was completed, the surgeon routinely checked both pupils and found that the left pupil was fully dilated without light reflex. In fear of exacerbation of the existing intracranial hemorrhage with progressive bleeding, the operation was hastily brought to an end. An urgent CT of the brain was immediately carried out but it revealed no obvious progression compared with the preoperative examination. The patient awaked in the postanesthesia care unit (PACU) uneventfully with the left pupil returning to normal condition.

BACKGROUND:Infraclavicular brachial plexus block has been widely used for surgical procedures below the mid humerus owing to its excellent anesthetic quality and ease of practice. However, what is the optimal upper arm position for carrying out the procedure still lacks consensus of opinion. The primary goal of this study was to determine the optimal upper arm position for coracoid infraclavicular block by ultrasonographic examination.METHODS:High-frequency (5-10 MHz) ultrasonographic examination on the vertical line 2 cm medial to the coracoid process was performed in 40 volunteers. We assessed the influence of four different upper arm positions on the topographic anatomy of the infraclavicular region. Ultrasonography-derived distances and morphometric measurements were applied to evaluate the optimal puncture site. The deviation of coracoid puncture site from the ultrasonographically modified ideal puncture site in distance was also recorded.RESULTS:When the upper arm was abducted 900, the brachial plexus was much closer to the skin (1.67 cm) and farther from the pleura (1.15 cm) as compared with other positions. In this position, the revealation of anterosuperior plexus relative to artery, identification of all three cords and pleura were 53.8%, 64.1% and 87.2%, respectively. We also found that as the upper arm was drawing from abduction to adduction the ideal puncture site tended to shift more inferiorly.CONCLUSIONS:We recommend the most optimal position for carrying out coracoid infraclavicular brachial plexus block is to abduct the upper arm 90 degrees with external rotation of the shoulder. Though ultrasonographic guidance is suggested for infraclaricular brachial plexus block, an optimal position for puncture site determined by anatomical landmark is also acceptable.

The purpose was to determine whether nalbuphine in low dose intravenous injection discontinued before the end of surgery provided well pain control and low complication rate in children undergoing minor surgery. Method: We conducted a retrospective patient chart review between January 2006 and June 2006. Eighty ASA class I-IT patients, aged from 2-10 yr were included. Anesthetic records and charts were reviewed to assess differences in 2 groups of patients: those who received preventive low dose of nalbuphine (0.1mg/kg) and those who did not till awake or OPS＞5. We assessed emergence time, highest pain score and complications. Main Results: Seventy-eight children completed the smdy. Two patients were excluded. The highest pain score was statistically significantly different between the two group, 1.50±2.26 in group N Vs 6.13±2.48 in group S (P＜0.05). Postoperative adverse effects such as delay discharge from PACU or postoperative nausea and vomiting were no significant difference. Conclusion: Our results show that in children undergoing elective minor surgery, the concurrent use of nalbuphine (0.1mg/kg) significantly reduces the pain scores without prolonging the time to discharge in this retrospective review.

BACKGROUND:Surface anatomic landmarks have traditionally been used to locate the brachial plexus in the interscalene groove. Head rotation can affect the orientation of neck vessels and may possibly affect the brachial plexus. The optimal degree of head rotation has been specified for better internal jugular vein cannulation but not for interscalene brachial plexus block. The purpose of this study was to evaluate the influence of head rotation on interscalene brachial plexus block.METHODS:We simulated the needle insertion in interscalene approach to brachial plexus with the ultrasound probe to mimic the needle in the manner of actual block in 53 volunteers. Ultrasound-derived measurements were recorded to evaluate the influence of head rotation on the approach including deviation from the imitative needle path to plexus center, depth of brachial plexus and vessel intersection.RESULTS:Medial deviation of the imitative needle path to the center of brachial plexus was found from all angles of head rotation. Increased head rotation angle of 0 degree, 15 degrees, 30 degrees, 45 degrees and 60 degrees from the midline was associated with increasing medial deviation. The brachial plexus became more superficial if head rotation was over 30 degrees than within the realm of 15 degrees. The likelihood of the stimulated needle path intersecting the internal jugular vein was lower than 5% for head rotation within 30 degrees and would become significantly higher for head rotation over 45 degrees.CONCLUSIONS:Whenever we perform interscalene brachial plexus block, the head rotation angle should not exceed 30 degrees. The measured medial deviation of surface landmark should be considered when it is used to approach interscalene brachial plexus.

BACKGROUND:The coracoid infraclavicular block first introduced by Whiffler provides a safer and easily approach than classic infraclavicular block. In this technique, the anatomy-based puncture site is 2 cm medial and 2 cm caudal from the coracoid process. This prospective study was purposed to evaluate the feasibility of surface landmark-based coracoid block by ultrasonography.METHODS:High-frequency ultrasonographic examination was performed in 80 volunteers along the vertical line 2 cm medial to the coracoid process. The C point (C) is defined as landmark-based puncture site. The U point (U) is defined as the ultrasonographically modified optimal puncture site. After identifying the neurovascular bundle, the extent of precision based on landmark was examined and ultrasonographic measurements were also done. Demographic data was applied to correlate with the deviation between C and U.RESULTS:The landmark-based puncture site for coracoid infraclavicular block was found to have a fair precision rate of 74.4%, although not high enough to provide a reliable puncture in daily practice. There was a significant trend toward a more superior puncture site of 2.95 mm (95% CI, 1.2-4.7). In female subjects, U was 5.12 mm (95% CI, 2.91-7.33) superior to C which was statistically significantly (P < 0.001). In male subjects, U was not significantly superior to C.CONCLUSIONS:Ultrasonographic guidance is suggested whenever anatomical precision is inadequate or meeting with great individual bodily variance which renders landmark-based technique difficult. However, if this facility is not available, the gender discrepancy in measurement should be seriously considered when coracoid process is used as the landmark.

Failure or difficulty in intubating the trachea can be either due to inability to visualize the glottis or some pathology at the level of or below the cords. This report describes a case of difficult intubation suspected of being related to neck scarring from previous surgery. Computed tomography (CT) was used to evaluate the patient's airway and revealed upper tracheal angulation. We describe a method to secure the airway in this patient with a two-person technique by rotating an oral endotracheal tube 180 degrees counterclockwise to adjust to the curvature of the trachea. Problems with intubation should be anticipated in patients with scarring of the neck, and equipment for aiding intubation should be on hand. Furthermore, we found that CT contributed to the assessment of the difficulty of intubation in this kind of patient.

Femoral nerve block (FNB) is by far the most useful lower extremity regional anesthetic technique for the anesthesiologist, and high-resolution ultrasonography is a useful tool with which to guide the performance of FNB. However, the relationships between the femoral nerve and the femoral artery in different lower extremity positions have rarely been discussed. The purpose of this study was to evaluate the relative positions of the femoral nerve and artery at different lateral rotational angles of the lower extremities using ultrasonographic imaging. We enrolled 41 healthy volunteers in this study. Two-dimensional ultrasonographic images of the femoral nerve were obtained using an ultrasound unit, in the inguinal crease, for four positions of the bilateral lower extremities: 0 degrees , 15 degrees , 30 degrees and 45 degrees lateral rotation of each extremity. The following assessments were made in each position: minimal skin-to-nerve distance (SN) and deviation of nerve-to-landmark (femoral artery pulsation) horizontal distance (NF). A trend towards lateral rotation of both lower extremities was identified. The Pearson correlation values between rotational degree to SN and rotational degree to NF were -0.216 and 0.430, with p values of 0.001 and less than 0.001, respectively. Body mass index had a good correlation ( r = 0.76-0.78) with SN. The results of our ultrasound study revealed that the more lateral the rotation of both lower extremities, the closer the femoral nerve was to the skin and the farther away it was from the femoral artery. In order to increase the success rate and decrease the rate of complications, a suggested lateral 45 rotation of both lower extremities is strongly recommended when performing FNB using the peripheral nerve stimulator technique or the field block technique. In any situation, individual ultrasound guidance is recommended for FNB whenever possible.

We report a young male patient who experienced seizure after local injection of 3 mL 2% lidocaine with epinephrine 1:200,000 around a recurrent nasal angiofibroma. After receiving 100% oxygen via mask and thiamylal sodium, the patient had no residual neurologic sequelae. Seizure immediately following the injection of local anesthetics in the nasal cavity is probably due to injection into venous or arterial circulation with retrograde flow to the brain circulation. Further imaging study or angiography should be done before head and neck surgeries, especially in such highly vascular neoplasm.

Acupuncture is generally accepted that there is clear evidence that acupuncture can be effective for nausea and vomiting associated with pregnancy, chemotherapy, and the postoperative period. Postoperative Nausea and Vomiting (PONV) is one of the dominant postoperative problems of pneumonperitoneal laparoscopic surgery which incidence was reported as high as 45%. Postoperative nausea and vomiting (PONV) is an important cause of delayed discharge from the recovery room and decreased patient satisfaction. Our study is designed to investigate whether P6 acupoint injections is effective as a preventive treatment for postoperative nausea and vomiting of adults receiving laparoscopic pneumonperitoneal surgery. We also examine the response between different sorts of injection agents. We collected 150 patients was randomly divided into 5 groups: (1) Control N group (Cn), bilateral P6 sham point injections with normal saline 1ml; (2) Control L group (Cl), bilateral P6 sham point injections with 1% lidocaine 1ml; (3) Experiment N group (En), bilateral P6 acupoint injection with normal saline 1ml; (4) Experiment L group(El), bilateral P6 acupoint injection with 1% lidocaine 1ml. (5) Reference (Rf), no acupoint injection used. We applied double-blinded method to follow up the events of postoperative nausea and vomiting which were recorded by another observer unknown about 5 groups for 24 hours. Incidence of PONV among Rf, Cn, Cl, En, El were 41%(12/30), 36%(11/30), 43%(13/30), 27%(8/30) and 33%(10/30). En group was found with significant difference in decreased incidence of PONV compared with other groups. But, no significant difference between El group and other three groups (Rf, Cn and Cl). In conclusion: P6 acupoint injections with normal saline may be an alternative, economic method to prevent early postoperative nausea and vomiting. 1%Lidocaine can block early antiernetic effect of P6 acupoint.

Ignition of the tracheal tube during laser microlaryngeal surgery under general anesthesia is an uncommon complication with potentially serious consequences. We present here a case of a patient with glottic stenosis following endotracheal intubation, who experienced this potentially catastrophic combustion during endoscopic arytenoidectomy, using a diode laser under general anesthesia via 60% FiO2, with an airway fire occurring at the tracheostomy tube and causing tubal damage and obstruction. The anesthetic connecting tube was immediately disconnected and the tracheostomy tube replaced. No adverse consequences to this patient's upper airway were noted during follow-up visits. Higher oxygen concentrations, the presence of combustibles, and the narrowness of the surgical field during endolaryngeal diode laser surgery are risk factors for airway fires.

Postherpetic neuralgia (PHN) is the most complication of Herpes zoster (HZ) and one of the most intractable neuropathic pains. The use of corticosteroids with or without other concomitant therapy for HZ and PHN is not guaranteed. Previous studies showed that epidural injection of steroids and local anesthetics or/and antiviral therapy in acute phase of herpes zoster is a promising therapy for reductions in the use of analgesics, the time to uninterrupted sleep, the time to resumption of usual activities ,and prevention of PHN. However, Corticosteroid therapy is seldom used in patients at risk for corticosteroid-induced toxicity (e.g., patients with diabetes mellitus or gastritis) and makes a restriction for these patients. We present a case of 67-year-old female patient with the history of diabetes mellitus who presented with impending diabetic ketoacidosis (DKA) 8 days after receiving 40 mg triamcinolone into the epidural space for prevention of PHN and relief of HZ with deafferentation pain. Further investigations of metabolic and endocrine sequelae of epidural corticosteroid, association between diabetic patient and the use of epidural steroid and the strategies of treatment and prevention of postherpetic neuralgia will be beneficial for clinicians in helping this kind of patients who suffered from this problem.