Uterotonic activity was determined in two synthetic prostaglandin derivatives designed for use in veterinary medicine: Remophan Spofa (99/104/89-C) and Glystrophan Spofa (the registration procedure is not yet finished). The uterotonic characteristics of these synthetic products are compared with those of the natural prostaglandins PG E2 and PG F2-alpha. The contractility of the smooth muscles of the uterus in vitro was measured in uterine slices of human and rat myometrium, using the modified Magnus-Kehrer apparatus. The new prostaglandin preparations showed a biphasic effect: their action depended on the concentration of the preparation in the reaction medium. The uterotonic activity of both synthetic products compares favourably with the uterotonic activity of PG F2-alpha. In the rat slice the Remophan Spofa derivative potentiates the action of PG F2-alpha and Glystrophan Spofa if it left to act in mixture.

ChemInformVolume 20, Issue 40 Heterocyclic Compounds ChemInform Abstract: Large-Scale Synthesis of Racemic “Corey Lactone”. I. VESELY, I. VESELY Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this authorV. KOZMIK, V. KOZMIK Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this authorV. DEDEK, V. DEDEK Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this authorJ. PALECEK, J. PALECEK Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this authorJ. MOSTECKY, J. MOSTECKY Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this authorI. STIBOR, I. STIBOR Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this author I. VESELY, I. VESELY Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this authorV. KOZMIK, V. KOZMIK Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this authorV. DEDEK, V. DEDEK Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this authorJ. PALECEK, J. PALECEK Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this authorJ. MOSTECKY, J. MOSTECKY Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this authorI. STIBOR, I. STIBOR Res. Dev. Div., Chem. Works Spolana, 277 11 NeratoviceSearch for more papers by this author First published: October 3, 1989 https://doi.org/10.1002/chin.198940185Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References I. VESELY, V. KOZMIK, V. DEDEK, J. PALECEK, J. MOSTECKY, I. STIBOR, Large-Scale Synthesis of Racemic “Corey Lactone”., Collect. Czech. Chem. Commun., 1989, 54, 1683. DOI: 10.1135/cccc19891683; 10.1135/cccc19891683 CASWeb of Science®Google Scholar Volume20, Issue40October 3, 1989 ReferencesRelatedInformation

Very convenient synthesis of Corey lactone–(3aα,4α,5β,6aα)-5-(1,1'-biphenyl-4-carbonyloxy)-hexahydro-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one (VI) was developed. The title compound was obtained in five steps starting from 7-anti-hydroxymethyl-5-exo-chloro-bicyclo[2.2.1]-heptan-2-one (I) in a very good overall yield.

AbstractThe optical resolution of the racemic title compound (I) can be performed in two different manners.

Synthese de deux cyclopenta [b] furannones-2 a partir de l'acide oxo-3 nortricyclene carboxylique-7

Substituted phenones II reacted with ethylene glycol and pyridinium perbromide, phenyltrimethylammonium tribromide, or dioxane dibromide give the corresponding α-bromoacetals I. The highest yields are obtained with dioxane dibromide, and a route is suggested in which the agent is generated in situ. The mass spectra of the compounds I are interpreted.

Chemischer InformationsdienstVolume 15, Issue 42 Heterocyclic Compounds ChemInform Abstract: ONE-STEP SYNTHESIS OF SUBSTITUTED 2-ARYL-2-(BROMOALKYL)-1,3-DIOXOLANES J. SVOBODA, J. SVOBODASearch for more papers by this authorJ. PALECEK, J. PALECEKSearch for more papers by this authorV. DEDEK, V. DEDEKSearch for more papers by this authorJ. MOSTECKY, J. MOSTECKYSearch for more papers by this author J. SVOBODA, J. SVOBODASearch for more papers by this authorJ. PALECEK, J. PALECEKSearch for more papers by this authorV. DEDEK, V. DEDEKSearch for more papers by this authorJ. MOSTECKY, J. MOSTECKYSearch for more papers by this author First published: October 16, 1984 https://doi.org/10.1002/chin.198442175Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume15, Issue42October 16, 1984 RelatedInformation

Journal Article A New Concept of the Recycle in Chromatography Get access M. Minárik, M. Minárik Institute of Chemical Process Fundamentals, Czechoslovak Academy of Sciences, 165 02 Prague 6 - Suchdol, Czechoslovakia Search for other works by this author on: Oxford Academic PubMed Google Scholar M. Popl, M. Popl Institute of Chemical Technology, 166 28 Prague 6, Czechoslovakia Search for other works by this author on: Oxford Academic PubMed Google Scholar J. Mostecký J. Mostecký Institute of Chemical Technology, 166 28 Prague 6, Czechoslovakia Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Chromatographic Science, Volume 19, Issue 5, May 1981, Pages 250–252, https://doi.org/10.1093/chromsci/19.5.250 Published: 01 May 1981 Article history Received: 16 April 1980 Revision received: 25 August 1980 Published: 01 May 1981

This chapter discusses instrumentation for high-performance liquid chromatography (HPLC) and medium-pressure liquid chromatography (MPLC). A typical high-performance liquid chromatograph consists of several components that constitute the sequence of the chromatographic separation process. On-line chromatographic equipment consists of a solvent delivery system (pumps and a gradient maker), injection system (sampling device), column system with temperature control, a detector connected with data system, and a fraction collector (if preparative chromatography is performed). The volume of a reservoir is primarily determined by the type of pumping system. For syringe pumps, a limited reservoir is used, equal to the volume of the pump. The material of the reservoir must be inert toward solvents (glass or stainless steel). In addition to efficient columns and sensitive detectors, pumps are very important components of HPLC systems. The pneumatic pumping systems are cheap, pulseless, and easy to maintain, and they easily allow stop flow sample application.

Partial optimization of conformation structure of quantum-chemical models of the stereoisomeric lactones I to IV has been carried out by the CNDO/2 method. The calculated energy characteristic and electron distributions have been used for discussion of some factors affecting retention of 5,6-trans-configuration in the key intermediate of prostaglandin syntheses (formulaI) with regard to conditions of the preparative experiments.

The field ionization of binary hydrocarbon mixtures of alkanes with alkynes and of 1-octyne with benzene for the characterization of bimolecular interactions of both types of molecule during the field ionization process was nvestigated. The formation of (M - 1)+ fragments of alkanes and of (M + CH3)+ ions of alkynes has been marked as the main characteristic feature of these reactions. The mechanism of the bimolecular fragmentation processes was closely studied by use of d22-n-decane, d12 cyclohexane and d6-benzene.

Zeitschrift für ChemieVolume 17, Issue 3 p. 97-99 Kurze Originalmitteilungen Über den Einfluß von Trialkyl(Aryl)phosphinsulfiden und -oxiden auf die Flüssig-Phasen-Kohlenwasserstoffoxydation Václav Trdlička, Václav Trdlička Institut für Erdöltechnologie und Petrolchemie der Chemisch-technologischen Hochschule, 166 28 Praha 6, Suchbatarova 5, ČSSRSearch for more papers by this authorJiřI Mostecký, JiřI Mostecký Institut für Erdöltechnologie und Petrolchemie der Chemisch-technologischen Hochschule, 166 28 Praha 6, Suchbatarova 5, ČSSRSearch for more papers by this author Václav Trdlička, Václav Trdlička Institut für Erdöltechnologie und Petrolchemie der Chemisch-technologischen Hochschule, 166 28 Praha 6, Suchbatarova 5, ČSSRSearch for more papers by this authorJiřI Mostecký, JiřI Mostecký Institut für Erdöltechnologie und Petrolchemie der Chemisch-technologischen Hochschule, 166 28 Praha 6, Suchbatarova 5, ČSSRSearch for more papers by this author First published: März 1977 https://doi.org/10.1002/zfch.19770170311Citations: 1AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume17, Issue3März 1977Pages 97-99 RelatedInformation

AbstractEs wird der beschleunigende Einfluß von Tributyl‐ bzw. Triphenylphosphinoxid auf die Oxidation von Tetralin bei 1 10°C durch Sauerstoff untersucht.

The application of the iodine-azide-induced reaction for the detection of thiophosphoryl compounds in thin-layer chromatographic systems is described. The detection limits of the derivatives tested were found to be at the nanomole level and depend on the nature of the P(S)n function, particularly on the degree of polarity of the PS bond and the number of sulphur atoms in the molecule. A comparison of the iodine-azide test reaction with other procedures used for thiophosphoryl compounds is presented. A procedure for the differentiation of thiophosphoryl compounds and sulphur compounds based on the combined molybdate procedure preceded by a preoxidation stage is demonstrated.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnalysis of saturated hydrocarbons by field ionization mass spectrometryMecislav. Kuras, Miroslav. Ryska, and Jiri. MosteckyCite this: Anal. Chem. 1976, 48, 1, 196–198Publication Date (Print):January 1, 1976Publication History Published online1 May 2002Published inissue 1 January 1976https://pubs.acs.org/doi/10.1021/ac60365a002https://doi.org/10.1021/ac60365a002research-articleACS PublicationsRequest reuse permissionsArticle Views80Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts