OBJECTIVE:The purpose of this study was to determine the relationship between cleft width and the residual amount of bone after bone grafting in 53 unilateral cleft lip and palate patients.STUDY DESIGN:The fate of the bone graft was determined by the residual amount of bone calculated from computed tomography scans taken immediately after surgery and 1 year postoperatively. Initial cleft width was measured on the computed tomography scans taken immediately after bone grafting.RESULTS:An average cleft width of 6.4 mm (range 3.0-12.2 mm) was found. The average amount of residual bone in the cleft area after 1 year was 64% of the initial bone graft. Linear regression analysis showed that a significant correlation (r = -0.29, P =.04) was found for cleft width in relation to the percentage of residual bone after 1 year.CONCLUSION:The regression analysis indicates that a relation between cleft width and the fate of the bone graft exists. Bone grafts in wider clefts are more prone to resorption than those in more narrow ones.

OBJECTIVEThe purpose of this study was to evaluate the outcome of bone grafts in cleft palate patients, thus assessing the amount of bone necessary to facilitate eruption-especially in the buccopalatal direction-of the permanent canine into the bone graft.STUDY DESIGNComputed tomography scans taken immediately postoperatively and 1 year postoperatively of 42 unilateral and of 8 bilateral cleft lip and palate patients who underwent surgery at the age of 9 years (early secondary bone graft) or 12 years (late secondary bone graft) were compared. Three slices from the computed tomography scans taken immediately after the surgery were selected from the center of the bone graft and were then compared with corresponding slices from the 1-year postoperative computed tomography scans. Statistical analysis was performed by using the Wilcoxon 2-sample rank sum test.RESULTSIn the unilateral cleft group, 70% of the transplanted bone remained in the cleft area after 1 year, whereas in the bilateral cleft group, only 45% of the initial bone graft remained after 1 year.CONCLUSIONNo statistically significant difference was found between early secondary bone grafting and late secondary bone grafting. In most cases, a sufficient amount of bone was present in the target area to facilitate eruption of the permanent canine.

Among non-Hodgkin's lymphomas occurring in childhood two major histologic subgroups can be identified: (1) Burkitt's lymphoma and (2) T-cell lymphoblastic lymphoma, an uncommon high-grade malignant non-Hodgkin's lymphoma. Although Burkitt's lymphoma with maxillofacial involvement is a well-documented disease, T-cell lymphoblastic lymphoma in the perioral region is rare. An unusual case of T-cell lymphoblastic lymphoma with initial oral manifestation in an 18-month-old child is presented.

Computed tomography (CT) was used to determine the fate of the bone graft in cleft lip and palate patients. Eight right-sided unilateral cleft lip and palate patients from the Free University Hospital in Amsterdam, treated with early, secondary bone grafting, were evaluated immediately after the operation and 1 year postoperatively. Approximately 70% of the volume of transplanted iliac crest bone was still present in the cleft area after 1 year.

Regional odontodysplasia is a developmental anomaly of dental tissues with characteristic clinical, radiographic, and histologic appearances. It most commonly affects the maxillary anterior teeth of both the primary and permanent dentition, and occurs in females twice as often as in males. The pathogenesis is unknown. The clinical and histopathologic findings of regional odontodysplasia in three patients are discussed.

A case of periapical cementous dysplasia is reported that over the course of 12 years developed into a progressive bone lesion. The diagnostic and therapeutic aspects are discussed.

In contrast to chronic inability to open the mouth, inadequate closure of the jaws seldom occurs. The present case describes a young women with hereditary hyperlipoproteinism on an anticoagulant who suddenly developed an unilateral open bite due to a hemarthrosis of the left TMJ. After aspiration of the accumulated blood in the temporomandibular joint, the open bite disappeared and the occlusion became normal.

Ninety selected patients with a benign or malignant lesion in the oral cavity were treated by cryosurgery. A clinical study was carried out during a 6-year period to investigate the value of cryosurgery as supplemental or substitute therapy. Good results have been obtained in the treatment of small to moderate, superficially situated angiomas. Cryotherapy has also been found to be satisfactory in the treatment of papillary hyperplasia of the palate. As symptomatic treatment we employed the freezing procedure to painful erosive lichen planus. Until now, a casual treatment has not been possible because of an unknown etiology. Used as symtomatic therapy, cryosurgery may be of some use in these cases, especially to relieve pain. Good results have been obtained in the treatment of oral leukoplakia. The pathologically changed mucous membranes could be completely eliminated in most of the cases without severe scar formation or impairment to functions. Cryosurgery for palliation was employed in 11 incurable tumors. Results have been disappointing. Twenty-one localized malignant neoplasms were treated by cryosurgery to cure. The tumor was completely destroyed in 67% of the cases.