A retrospective study of 214 pregnancies in 100 consecutive patients with endometriosis revealed a significant increase (P < .01) in spontaneous abortions among women who conceived within 4 years prior to the diagnosis of endometriosis. A comparison of pregnancy outcome in a second group of 65 patients revealed a significant decrease (P < .01) in the spontaneous abortion rate following conservative surgery for endometriosis. Of 37 conceptions before surgery, 46% (17) were aborted spontaneously; after conservative surgery only 8% (4) of 50 conceptions terminated in abortion.

Sixty-five infertile patients with moderate or severe endometriosis were treated with conservative surgery. Acosta's classification was used to demonstrate the extent of disease. In 48 women whose partners were normally fertile, 65% conceived, and in 17 whose partners were deficient, 35% achieved pregnancy. The extent of disease, age at the time of surgery, and length of infertility prior to surgery appeared to be significant factors. To intelligently give a prognosis prior to surgery and to achieve maximum pregnancy yield from the surgery, it is important to perform conservative surgery for endometriosis within the context of a complete infertility evaluation.

ginning of the last menses 8 weeks before testing. However, when the 24, hour samples were used, both gave positive results. The explanation is not definite. It may be that early during pregnancy in some individuals the concentration of urinary gonadotropin is not significantly increased during the night or that the Placental secretion of this hormone in some women is not too high in the very early stages of gestation. The Burdick pregnancy test is an exceedingly valuable tool not only in the diagnosis of normal or abnormal gestation but apparently in the study of such pathologic conditions as hydatidiform mole and choriocarcinoma. Because of its validity, it may serve the specialist in the study of many unknown problems of normal and abnormal placental secretion,