Nuclear power plants (NPPs) transfer electricity using off-site power systems. Wildfires can disrupt these systems and cause a loss of off-site power, which can impact the operation of NPPs. In South Korea, wildfire incidents in 2000 and 2022 interrupted the operation of off-site power systems, affecting the NPPs. Furthermore, rising temperatures due to climate change are increasing the frequency of wildfires. Therefore, NPPs are expected to become more vulnerable to wildfires. Wildfire hazard maps are necessary for analyzing the impact of wildfires on NPPs. This paper proposes a methodology for generating a wildfire hazard map via Monte Carlo simulation. The proposed methodology was applied to the vicinity of the Hanul NPP, and a wildfire hazard map was generated.

INTRODUCTION:We aimed to investigate the correlation between spinal sarcopenia, spinal sagittal balance (SSB), and spinal function in older women living in rural areas versus those of the older urban women in our previous study.METHODS:Twenty-five older rural-dwelling women aged more than 70 years were compared with 24 older urban-dwelling women from our previous study. Demographic variables, conventional and spinal sarcopenic indices, variable functional outcome parameters, occupational state, and exercise participation rate were evaluated. We also measured the isometric back extensor strength, radiological parameters for SSB on whole-spine radiography, and volumetric parameters of the lumbar extensor muscle on computed tomography.RESULTS:There were no significant intergroup differences in demographic variables or the prevalence of sarcopenia. Older women in rural areas had greater handgrip strength than those in urban areas (22.7&plusmn;3.7 kg v 20.0&plusmn;3.4 kg, p=0.010). However, their mean lumbar lordosis angle was lower (31.7&plusmn;15.3&deg; v 42.3&plusmn;11.2&deg;, p=0.012). Isometric back extensor strength was lower in rural women than in urban women. The vocational activity participation rate of rural women was significantly higher (84% v 12.5%, p<0.001), whereas their exercise participation rate was significantly lower (60% v 92%, p<0.001).CONCLUSION:Older women in rural areas had greater handgrip strength and vocational participation rates but lower back extensor strength and exercise participation rates. Therefore, more attention is needed for healthcare services to support their spinal health and exercise habits.

Supplementary Figures 1-4, with Legends from Homeobox Msx1 Interacts with p53 Tumor Suppressor and Inhibits Tumor Growth by Inducing Apoptosis

Background Ogden type IV tibial tuberosity fractures, defined as a type of fracture with posterior–inferior metaphyseal extension (Salter-Harris type II variant), are uncommon but challenging pediatric fractures. The purpose of this study was to investigate the clinical and radiological presentation and associated surgical outcomes. Methods Ten previously healthy patients who had been surgically treated at the authors’ institution between 2015 and 2018 with at least 2 years of postoperative follow-up were included. Demographic, clinical, and radiological characteristics and treatment/follow-up data were investigated. Results All included patients were male. All injuries resulted from jump-landings. Unacceptable remaining angular deformity after closed reduction, particularly increased posterior tibial slope angle, was the leading cause of surgery. All preoperative magnetic resonance images (MRIs) showed entrapped periosteum on the anteromedial side of the proximal tibial physis. Surgical removal of the entrapped periosteum achieved successful reduction. Metaphyseal fracture angles between the fracture plane of the metaphyseal beak and the posterior tibial condyle on the axial image of MRI were relatively constant, with an average of 24.3° ± 6.0°. Mean bone age at the time of trauma was older than mean chronological age (16.4 ± 1.0 years vs. 14.6 ± 1.1 years, respectively; p = 0.005). All patients reached skeletal maturity within 2 postoperative years, with little posttraumatic residual height growth (mean, 1.6 ± 0.7 cm from injury to skeletal maturity). At final follow-up, no patients showed significant angular deformity, tibial length discrepancy, or functional deficit. Conclusions In healthy adolescents, Ogden type IV tibial tuberosity fractures typically occur by jump-landing injuries, when they have little residual growth remaining. Therefore, accurate fracture reduction was required because of limited remodeling potential. Patients with unacceptable reduction should be investigated for entrapped periosteum on the anteromedial side of the physis because it was the primary obstacle in achieving adequate reduction.

Although the loss of skeletal limb muscle mass and muscle strength in the elderly have been demonstrated, the aging process of the back muscles to maintain core stability is not well known. This 1-year prospective observational study aimed to investigate the natural aging course of the lumbar extensor muscles (LEMs) compared with the extremity muscles and determine whether muscle strength or mass decreases more in community-dwelling older women. Twenty-four older urban-dwelling women aged 70 years or older were initially enrolled. Their demographic variables, conventional and spinal sarcopenia indices, and functional outcome parameters were evaluated. We also measured back extensor strength, radiological parameters for spinal sagittal balance on whole-spine radiography, and volumetric parameters of the LEM on computed tomography. After the exclusion of 6 subjects, 18 older women were finally analyzed. All variables related to extremity muscle mass, muscle strength, physical performance, and LEM volume declined over the study period, but the changes were insignificant. However, back extensor strength decreased significantly (median, first, and third quartile: 35.20 [30.80, 44.00] N to 31.40 [29.25, 37.90] N, P = 0.026). Among spinal sagittal balance-related parameters, lumbar lordosis (44.25 [39.30, 47.35]° to 43.15 [31.43, 45.75]°, P = 0.043) and sagittal vertical axis (33.85 [3.57, 58.75] mm to 45.15 [25.35, 58.68] mm, P = 0.004) showed significant changes during the study. When the natural aging course of LEM in women aged 70 years or older was observed for 1 year, muscle mass decreased less than back extensor strength and spinal sagittal balance. Measurements of back extensor strength and spinal sagittal balance are necessary for the clinical evaluation of spinal aging.

One of the technical challenges in multi-unit probabilistic safety assessment (MUPSA) is dealing with numerous combinations of plant operational states (POSs) for each nuclear power plant unit. Since the number of possible combinations of POSs increases exponentially with the number of units, it is impractical to develop separate MUPSA models and assess the risk for each POS combination. This paper proposes a pragmatic approach to modeling combinations of POSs for each reactor unit in MUPSA involving up to 10 reactor units. This approach does not focus on selecting representative POS combinations but rather on screening out non-risk-significant accident sequences in a stepwise manner according to the model quantification results. The effectiveness of the approach is demonstrated by application to cases with four different numbers of units. As a result, in the 2-, 4-, and 6-unit cases, the site and multi-unit core damage frequency (CDF) due to a multi-unit loss of offsite power initiating event are successfully calculated without screening out any accident sequences for each unit. In the 10-unit case, the quantification fails without screening, but it succeeds after reducing the model size by about 43% via the exclusion of the accident sequences in each integrated single-unit model with a CDF contribution of less than 0.1%. The results show that the minimal cut sets obtained in each case cover many POS combinations and that most non-risk-significant POS combinations can be truncated by the cutoff value of 1E-14/yr. In addition, comparing the quantification results according to the stepwise screening criteria shows that the proposed approach can effectively reduce the computational burden in MUPSA without losing much accuracy or realism.

The worldwide consumption of eggs is very high, leading to about 250,000 tons of eggshell membrane (ESM) waste annually. The present research thus investigated the potential use of ESM as an inexpensive and abundant adsorbent for Reactive Red 120 (RR120) in aqueous solutions, a widespread hydrophilic azo dye used in the textile industry. The chemical structure and morphology of ESM were characterized using various spectroscopic methods, including scanning electron microscopy, Fourier transform infrared spectroscopy, and elemental analysis. It was found that natural ESM has a porous structure and surface functional groups that are suitable for the adsorption of the target molecules. The impact of the operating conditions, including the variation in the pH and temperature, on the RR120 sorption capacity and mechanisms of ESM was also analyzed. The maximum monolayer adsorption ability of ESM for RR120 was found to be 191.5 mg/g at 318 K, and the sorption process was spontaneous and endothermic. The adsorption of RR120 onto ESM was significantly influenced by the solution pH and the use of NaOH as eluent, indicating that the driving force for this adsorption was electrostatic attraction. Subsequent desorption experiments using 0.1 M NaOH resulted in satisfactory recovery efficiency. Kinetic, isothermic, and thermodynamic analysis was also conducted to support the experimental findings. The experimental results for the adsorption kinetics of ESM were fitted by a pseudo-second-order model. In conclusion, ESM has the potential to be utilized as an eco-friendly and cost-effective adsorbent for the removal of RR120 from aqueous solutions.

This study presents and develops a textile type touch sensor structural design that is easy to implement. First, the design of the touch sensor circuit finds the size of the switch with the easiest finger contact and selects a structure with a long circuit with the lowest resistance value. An experiment is performed on a change in an electrostatic capacitance value that accompanies the distance on the electrode and the magnitude of the electrode area of the structure; however, the structure having the distance on the electrode and the large electrode area shows the best resistance change. The laundry assessment was conducted three times at a time and ten times at a time with an average standard deviation less than one ohm, with little change in resistance. Consequently, there were no problems with durability and performance for laundry. Finally, in the bending evaluation, the difference in resistance can be seen between 1-2 ohms and was developed as a smart wearable in the future; in addition, there was no problem as a difference in resistance can be seen between 1 and 2 ohms.

AbstractBackgroundHere, we aimed to propose novel lateral whole‐body dual‐energy X‐ray absorptiometry (lateral DXA) as a simple tool for measuring spinal muscle mass and investigate the feasibility of lateral DXA to measure lumbar paraspinal muscle (LPM) mass compared with lumbosacral spine three‐dimensional magnetic resonance imaging (3D MRI).MethodsTwenty consecutive participants were enrolled from a prospective observational cohort (SarcoSpine study). Lateral DXA was scanned with each participant in the lateral decubitus position. The region of interest was defined to analyse the LPM mass. LPM total volume, LPM cross‐sectional area at the L3 mid‐vertebra and L4/5 mid‐disc levels and each signal intensity were measured by 3D MRI. Isokinetic and isometric back extensor muscle strengths as well as back extensor endurance were examined. The correlation between lateral DXA‐based mass (weight) and 3D MRI‐based LPM volume was analysed.ResultsThe mean age of the 20 participants (15 women, 5 men) was 72.2 ± 4.9 years. LPM mass by lateral DXA was positively correlated with LPM volume by 3D MRI (β = 0.333, r = 0.692, p < 0.001) and negatively correlated with signal intensity of the total LPM (β = −0.263, r = −0.530, p = 0.016). LPM mass was also correlated with appendicular limb muscle mass, handgrip strength and gait speed as well as back extensor endurance (r = 0.620, p = 0.004).ConclusionsOur data suggest that LPM mass assessed by lateral DXA was positively correlated with LPM volume by 3D MRI in older adults. Lateral DXA may be a potential substitute for the cross‐sectional area measurement of LPM mass. Further studies are required to validate this lateral DXA technique.

Introduction: Spinal sarcopenia is a multifactorial disorder associated with the atrophy of and fatty changes to the paraspinal muscles. We previously developed the concept of spinal sarcopenia in community-dwelling older adults and investigated the association between conventional sarcopenic indices and spinal sarcopenia. However, interventional studies of spinal sarcopenia are lacking. This pilot study will aim to evaluate the effectiveness of a combined exercise and nutrition intervention for treating spinal sarcopenia. Methods and analysis: This open-label single-arm prospective study will include 35 community-dwelling older women who were diagnosed with spinal sarcopenia in our previous cohort study. The 12-week combined intervention will consist of back extensor strengthening exercise and nutritional supplementation. The primary outcome of this study will be isometric back extensor strength after the 12-week intervention. All functional and radiographic outcomes will be measured at 0, 12, and 24 weeks post-intervention. The data will be analyzed using the intention-to-treat principle.

This study investigates the degradation of the heat transfer performance of a closed-circuit intermediate natural circulation heat transport loop used as a passive safety system in a nuclear power plant (NPP). The degradation arises from the strong thermal-hydraulic (TH) coupling of the loop operating characteristics, saturation temperature and pressure, and natural circulation flow rate, which determine the heat rejection rate to the TH boundary conditions imposed on the hot side of the loop by the transitory state of the primary reactor coolant system (RCS) of the NPP. Several operator actions related to a feed-and-bleed emergency operating procedure (F&B) are postulated, and system TH code simulations are performed to demonstrate how the F&B can induce two-phase flow conditions in the RCS. Natural circulation two-phase flow regimes in the RCS hot leg can significantly reduce the heat transfer to the circulating working fluid of the interfacing heat transport loop over long periods, sometimes lasting over 24 h, of passive system mission time. A transient performance indicator for the passive system mission is introduced for use in the passive reliability assessment and quantitative comparison of transient simulations. The need to consider human factors in the design and operation of NPP passive safety systems is stressed.

BACKGROUD:Many studies have reported injury characteristics of individual traumatic situations. However, a comparative analysis of specific risks is meaningful to better understand injury characteristics and help establish injury-prevention measures. This study was conducted to investigate and compare injury characteristics in children and adolescents by various outdoor traumatic situations.METHODS:Outdoor traumatic situations were determined and classified into physical activity-related injury (n = 3,983) and pedestrian (n = 784) and passenger (n = 1,757) injuries in traffic accidents. Home injury (n = 16,121) was used as the control group. Then, the characteristics of each outdoor trauma were compared with 1:1 matched indoor trauma (among home injuries); each outdoor traumatic situation's predisposing risk for the injured body part, injury type, and injury severity were analyzed; and changes by age of frequency ranking among physical activity-related injuries were investigated.RESULTS:Outdoor trauma showed higher risks for limb injuries (injured body part), fracture and muscle/tendon injuries (injury type), and severe injuries (severity) than indoor trauma. Various outdoor traumatic situations presented different predisposing effects on injury characteristics. Among physical activity-related injuries, bicycle injury was commonest across all ages, and playing activities were common causes for injury for individuals of age < 9 years, whereas sports activities overwhelmed the common causes thereafter.CONCLUSIONS:The findings would help to better understand the specific injury risk of various outdoor traumatic situations and may potentially facilitate the establishment of more effective injury-prevention measures.

Background: In the Korean medical system, the severity classification for a specific disease depends primarily on its nationwide admission rate in tertiary hospitals. Inversely, one of the important designation criteria for a tertiary hospital is the hospital's treatment ratio of patients classified as having a specific severe disease. Most diseases requiring pediatric orthopaedic surgery (POS) are not currently classified as high severity in terms of disease severity. We investigated the admission rates for the representative POS diseases in tertiary hospitals and compared these rates with those for adult orthopaedic surgery (AOS) diseases. Methods: Seven POS diagnoses and three AOS diagnoses were selected based on frequency of admission. Nationwide sample data were used to investigate the admission rates for these representative diagnoses from 2008 to 2017. Results: Six of the seven frequent POS diagnoses presented high admission rates in tertiary hospitals (62.5-92.3%). In contrast, all frequent AOS diagnoses presented low admission rates in tertiary hospitals. Conclusion: The admission rates of frequent POS diagnoses in tertiary hospitals are high. Considering that these rates are the most important factors for the classification of disease severity, POS diseases seem to be underestimated in terms of severity. This may lead to a tendency for tertiary hospitals to intentionally reduce the admission of children with POS diseases. As a result, these children may not receive appropriate professional care. Therefore, for the disease severity, POS diseases should be classified differently from general AOS diseases by using different criteria reflecting the patient's age.

PURPOSE:This study investigated the initial angular deformity of proximal tibial metaphyseal fracture in children and its recovery during follow-up according to the cause of injury. METHODS:Prospective data about the patients with a proximal tibial metaphyseal fracture at the age less than six years and available follow-up data at two years post-trauma were retrospectively reviewed. They were grouped into trampoline-related injuries (TRI) and non-TRI groups based on the cause of injury. Proximal tibial valgus and recurvatum angles were measured to assess angular deformity on the coronal and sagittal planes, respectively. RESULTS:A total of 47 patients (33 TRI and 14 non-TRI) were included. Initially, the valgus angles were -1.5° in TRI and 1.6° in non-TRI groups (p < 0.001) and the recurvatum angles were 7.8° in TRI and 4.1° in non-TRI groups (p = 0.048). After two-year follow-up, the valgus angles were 0.2° in TRI and 0.9° in non-TRI groups (p = 0.070), and the recurvatum angles were 6.5° in TRI and 2.3° in non-TRI groups (p = 0.001). CONCLUSION:For children with a proximal tibial metaphyseal fracture, the initial coronal deformity was different according to the injury cause (varus in TRI whereas valgus in non-TRI). Although there was a near complete recovery after approximately two years of follow-up in the coronal deformities, the sagittal deformity (genu recurvatum) seems to recover incompletely or tardily, especially for those caused by TRI. LEVEL OF EVIDENCE:III.

As the emerging demand for electronic devices that are simple, cost effective and capable of rapid fabrication has increased, novel fabrication techniques for designing and manufacturing such devices have attracted remarkable research interest. One method for prototyping these electronic devices is to draw them using a handwriting tool that is commonly available. In this work, we demonstrate a transistor and complementary logic inverter that are directly drawn using a brush and that are based on solution-based materials such as semiconducting carbon nanotubes (CNTs), silver ink and paste, and cross-linked poly(4-vinylphenol) (cPVP). The directly drawn CNT thin-film transistor (TFT) has p-type behavior due to the adsorption of oxygen and moisture, a high current on/off ratio (approximately 10(3)), and a low operating voltage. By employing a solution-based chemical doping treatment with an amine-rich polymer, polyethyleneimine (PEI), that has strong electron-donating ability, the drawn p-type CNT-TFT is successfully converted to an n-type CNT-TFT. Therefore, we fabricate a drawn complementary logic inverter consisting of the p-type CNT-TFT and PEI-treated n-type CNT-TFT and evaluate its electrical performance.

Background: Postoperative pain assessment in children is crucial for proper nursing care. However, research on the agreement of these assessments with a patient's self-reported pain level is lacking. The aim was to investigate the agreement between patients' subjective postoperative pain and corresponding observers' pain assessments. Methods: In children who underwent orthopedic limb surgery, we investigated the agreement between their reported pain levels and observers' pain assessments using the Numeric Pain Rating Scale (NPRS) and the Faces Pain Scale-Revised (FPS-R) on postoperative day 1. The parents (specifically the mother) and clinicians (a doctor and a nurse in the field of pediatric orthopedics) participated as observers. Reliabilities using intraclass correlation coefficients (ICCs) and correlations using Spearman's coefficients ( r s ) were calculated. Results: The patients' pain intensities (2.1± 2.1 [NPRS] and 2.0 ± 1.9 [FPS-R]) were overestimated by parents (2.5 ± 2.0 [NPRS], p = .022), but underestimated by clinicians (1.5 ± 1.2 [NPRS], p < .001, and 1.5 ± 1.2 [FPS-R], p = .006). The overall reliabilities between parents and patients were good (ICCs > 0.75 for both NPRS and FPS-R), and the correlations between them were even strong in some circumstances, such as when the patient was a girl, the diagnostic type was a disease, or the lower extremity was operated ( r s s > 0.7). However, the agreements between clinicians and patients were only moderate. Conclusions: The subjective pediatric postoperative pain intensities had different agreements according to the observers. The parents' assessments should be considered for the accurate assessments, but their tendency to overestimate their children's pain should also be taken into account.

One fundamental element of probabilistic safety assessment (PSA) is the initiating event (IE) analysis. Since IE frequencies can change over time, time-trend analysis is required to obtain optimized IE frequencies. Accordingly, such time-trend analyses have been employed to estimate industry-average IE frequencies for use in the PSAs of U.S. nuclear power plants (NPPs); existing PSAs of Korean NPPs, however, neglect such analysis in the estimation of IE frequencies. This article therefore provides the method for and results of estimating Korean industry-average IE frequencies using time-trend analysis. It also examines the effects of the IE frequencies obtained from this study on risk insights by applying them to recently updated internal events Level 1 PSA models (at-power and shutdown) for an OPR-1000 plant. As a result, at-power core damage frequency decreased while shutdown core damage frequency increased, with the related contributions from each IE category changing accordingly. These results imply that the incorporation of time-trend analysis leads to different IE frequencies and resulting risk insights. The IE frequency distributions presented in this study can be used in future PSA updates for Korean NPPs, and should be further updated themselves by adding more recent data.