The bioassay-guided fractionation of a dichloromethane extract from the roots of Synaptolepis kirkii using neuronal viability as a model allowed the isolation of the new daphnane orthoester kirkinine (1a) as a powerful neurotrophic constituent.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTranslactonization in erythromycinsIsaac O. Kibwage, Roger Busson, Gerard Janssen, Jos Hoogmartens, Hubert Vanderhaeghe, and Johan BrackeCite this: J. Org. Chem. 1987, 52, 6, 990–996Publication Date (Print):March 1, 1987Publication History Published online1 May 2002Published inissue 1 March 1987https://pubs.acs.org/doi/10.1021/jo00382a004https://doi.org/10.1021/jo00382a004research-articleACS PublicationsRequest reuse permissionsArticle Views437Altmetric-Citations52LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

ChemInformVolume 18, Issue 37 Natural Products ChemInform Abstract: Translactonization in Erythromycins. I. O. KIBWAGE, I. O. KIBWAGE Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this authorR. BUSSON, R. BUSSON Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this authorG. JANSSEN, G. JANSSEN Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this authorJ. HOOGMARTENS, J. HOOGMARTENS Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this authorH. VANDERHAEGHE, H. VANDERHAEGHE Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this authorJ. BRACKE, J. BRACKE Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this author I. O. KIBWAGE, I. O. KIBWAGE Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this authorR. BUSSON, R. BUSSON Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this authorG. JANSSEN, G. JANSSEN Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this authorJ. HOOGMARTENS, J. HOOGMARTENS Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this authorH. VANDERHAEGHE, H. VANDERHAEGHE Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this authorJ. BRACKE, J. BRACKE Med. Chem. Sect., Lab. Chem., Natl. Inst. Diab., Dig., Kidney Dis., Bethesda, MD 20892, USASearch for more papers by this author First published: September 15, 1987 https://doi.org/10.1002/chin.198737334AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume18, Issue37September 15, 1987 RelatedInformation