The most significant conclusion from the data collected is that the 2-nitro-1,1-bis-p-chlorophenylpropane and/or its metabolites are very poorly absorbed from the surface of the leaf and accordingly are not translocated throughout the plant to any significant degree. No measurable amount of the insecticide was found in the roots or in the bean at any time intervals over the 40 day span of study following foliar application. Only minor amounts of the compound representing about 3 percent of that originally applied to the leaf was observed in the stem and untreated leaves, signifying a small amount of absorption and translocation within the first 9 days after application.
Labeled compounds were used to study the metabolism of salicylates in rats. A method, electrophoretic separation, was developed to identify the oxidative metabolites. Analysis of tissue extracts by this method generally revealed only the administered compounds. However, gentisic acid was found in the pituitary region of fevered rats administered either acetylsalicylic or salicylic acid. It was not found in the pituitary after administration of these compounds to nonfevered rats or after administration of gentisic acid to fevered rats.