Sporadic references to peripheral neuropathy complicating rheumatoid arthritis appeared as long ago as the last century.The early literature is reviewed by Irby, Adams, and Toone (1958) and by Hart and Golding (1960).During the past ten years neuropathy has been mentioned in a number of papers dealing primarily with the vascular complications of rheumatoid arthritis or with treatment of the disease with corticosteroid hormones.A recent comprehensive account of arteritis in rheumatoid disease by Schmid, Cooper, Ziff, and McEwen (1961) reviews these communications in detail.Hart, Golding, and Mackenzie (1957) were the first to describe a definitive series of patients with neuropathy and rheumatoid disease.Similar publications then followed from Mason and Steinberg (1958), Irby et al. (1958), Johnson, Smyth, Holt, Lubchenco, and Valentine (1959), Ansell (1960), Hart and Golding (1960), Steinberg (1960), and Ferguson and Slocumb (1961).The association has become well recognized by those treating large numbers of patients with rheumatoid arthritis, but is perhaps less familiar to neurologists and general physicians.Moreover, certain features of the condition have not yet received adequate attention.The present paper describes 30 cases of rheumatoid arthritis' and peripheral neuropathy personally examined at Hammer- smith Hospital and at the Canadian Red Cross Memorial Hospital, Taplow, during the past two years.These comprise most patients with rheumatoid neuropathy attending the two centres during this period. Clinical ExaminationThe examination of patients with rheumatoid arthritis and neurological complications is difficult and time-consuming.The history of arthritis is usually long, the details of its fluctuating course being more or less accurately recorded in voluminous dossiers.Patients often have difficulty in giving accurate information if to their arthritic symptoms are added neuritic ones, which may themselves evolve in a variety of ways.Neuritic pains may be confused with those of arthritis, the distribution of numbness may be difficult to recall, and com- plaints of weakness are notoriously hard to evaluate.For example, many patients with rheumatoid arthritis complain of weak hands, when what they mean is a combination of stiffness,

4 she was admitted to the Luton and Dunstable Hospital with what was diagnosed as lupus vulgaris of the right calf -and an abscess underlying it from which tubercle bacilli were isolated. This healed up satisfactorily, but the following year contractures of the right elbow and of the wrists were noticed, without either pain or swelling. Left adrenalectomy was performed by Mr. Broster in 1944 because of excessive pubic hair and marked clitoral enlargement. 17-Ketosteroid excretion was then 9.8 mg./day. Following the operation, increasing deformities